Abstract: Event management system and method. Events comprise physical and logical attributes. Tuples are created to identify a set of logical attributes. The tuples are arranged in hierarchized relations by creating binarized co-occurrence matrices, each co-occurrence matrix reflecting different time intervals and indicate occurrence of tuples in time windows of the time intervals. Tuple pairs are analyzed to determine probabilistic score related to co-occurrence, and tuple families are created from tuple pairs based on the probabilistic score. From tuple families, events are used to extract tuple instances including physical attributes, which are arranged as tuple-instance families using the corresponding tuple families as reference.

Abstract: Event management system and method. Events comprise physical and logical attributes. Tuples are created to identify a set of logical attributes. The tuples are arranged in hierarchized relations by creating binarized co-occurrence matrices, each co-occurrence matrix reflecting different time intervals and indicate occurrence of tuples in time windows of the time intervals. Tuple pairs are analyzed to determine probabilistic score related to co-occurrence, and tuple families are created from tuple pairs based on the probabilistic score. From tuple families, events are used to extract tuple instances including physical attributes, which are arranged as tuple-instance families using the corresponding tuple families as reference.

Abstract: The invention provides a method for managing a plurality of events, wherein each event comprises physical attributes and logical attributes by creating tuples with the events with the same logical attributes, providing a set of hierarchized relations between tuples, by means of a pipeline algorithm, wherein parent-child relations are provided between tuples, classifying the tuples in families, each family contains all the tuples related according to the parent-child relation provided by the pipeline algorithm, identify the parent tuple of each family, defined as the tuple which has at least one children and has no parent and present the parent tuples, together with the physical attributes of the events associated to each parent tuple.

Abstract: The invention provides a method for managing a plurality of events, wherein each event comprises physical attributes and logical attributes by creating tuples with the events with the same logical attributes, providing a set of hierarchized relations between tuples, by means of a pipeline algorithm, wherein parent-child relations are provided between tuples, classifying the tuples in families, each family contains all the tuples related according to the parent-child relation provided by the pipeline algorithm, identify the parent tuple of each family, defined as the tuple which has at least one children and has no parent and present the parent tuples, together with the physical attributes of the events associated to each parent tuple.

Abstract: Present invention, “BiggieBills”, is an interactive business strategy multi-player game played among 4 to 8 teams using plurality of cards. It can be played “Face to Face” or “Online.” The teams play “Growth Cards” to progress from Stage 1 to 4 while managing possible “Challenge Cards” played by opposing teams, managing the random changes in “Industry Rules” every “Business Cycle,” and attempt to earn “Bonus Cards.” The unique value propositions are: a) dynamic real-time experience; b) knowledge from the field of strategic management for the managers (students); c) the debrief provides the core learning as a follow-up to the game; and d) customization of the game is possible by altering industry conditions to suit client needs. BiggieBills has a three-pronged approach: a) corporate training; b) education (undergraduate, graduate, executive); and c) entertainment. It may be redesigned to teach subjects such as entrepreneurship, economics, innovation management and general business.

Abstract: Present invention, “BiggieBills”, is an interactive business strategy multi-player game played among 4 to 8 teams using plurality of cards. It can be played “Face to Face” or “Online.” The teams play “Growth Cards” to progress from Stage 1 to 4 while managing possible “Challenge Cards” played by opposing teams, managing the random changes in “Industry Rules” every “Business Cycle,” and attempt to earn “Bonus Cards.” The unique value propositions are: a) dynamic real-time experience; b) knowledge from the field of strategic management for the managers (students); c) the debrief provides the core learning as a follow-up to the game; and d) customization of the game is possible by altering industry conditions to suit client needs. BiggieBills has a three-pronged approach: a) corporate training; b) education (undergraduate, graduate, executive); and c) entertainment. It may be redesigned to teach subjects such as entrepreneurship, economics, innovation management and general business.

Abstract: Peptides which mimic a loop on the &ggr;-chain that either interact with a cytokine or a &ggr;-chain partner receptor chain of a heterodimeric cytokine receptor are disclosed. The peptides consist of 5-25 amino acids and inhibit signal transduction mediated by cytokine:receptor binding of cytokines that bind to receptors that comprise a &ggr;-chain. Pharmaceutical compositions that comprise the peptides are disclosed. Methods of inhibiting signal transduction mediated by cytokine:receptor binding of cytokines that bind to receptors that comprise a &ggr;-chain, methods of inhibiting cytokine mediated cell growth, proliferation, function or activity, methods of treating patients suffering from a disease disorder or condition characterized by cytokine mediated cell growth, proliferation, function or activity and methods of preventing a condition characterized by cytokine mediated cell growth, proliferation, function or activity are disclosed.

Abstract: Compounds that inhibit CD8 mediated T cell activation and that have a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 38-46 and/or 53-56 and/or 60-67 and pharmaceutical compositions comprising such compounds are disclosed. Methods of inhibiting activation of a human T cell are disclosed. The methods comprise contacting a T cell with a compound that inhibits CD8 mediated T cell activation and that has a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 38-46 and/or 53-56 and/or 60-67. Methods of treating an individual suspected of suffering from or susceptible to graft versus host disease and/or organ rejection are disclosed. The methods comprise administering an effective amount of a compound that inhibits CD8 mediated T cell activation and that has a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 34-46 and/or 53-56 and/or 60-67.

Abstract: Compounds that inhibit CD8 mediated T cell activation and that have a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 53-56 and/or 60-67 and pharmaceutical compositions comprising such compounds are disclosed. Method of inhibiting activation of a human T cell are disclosed. The methods comprise contacting a T cell with a compound that inhibits CD8 mediated T cell activation and that has a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 53-56 and/or 60-67. Methods of treating an individual suspected of suffering from or susceptible to graft versus host disease and/or organ rejection are disclosed. The methods comprise administering an effective amount of a compound that inhibits CD8 mediated T cell activation and that has a molecular surface that corresponds to the molecular surface of human CD8 at amino acids 53-56 and/or 60-67.