Patents by Inventor Syed Aziz Imam QUADRI

Syed Aziz Imam QUADRI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESSES FOR THE PREPARATION OF ROXADUSTAT AND INTERMEDIATES THEREOF
    Publication number: 20220340532
    Abstract: The present invention provides new procedure and intermediates for the preparation of Roxadustat (1) comprising: (A) reducing a compound of formula 3?, 3? or a mixture thereof: (3?), (3?) wherein Pg is H or a OH protecting group, Ri is alkyl, aryl, or arylalkyl; R2, R3, R4, and Rs each independently represents alkyl, arylalkyl or alkenyl, or R2 and R3 and/or R4 and Rs, taken together with the nitrogen atom to which they are bonded, each independently form a ring selected from: (I), wherein R6 is H or CI-6 alkyl; R7 is Ci to C6 alkyl and X— is an anion selected from the group consisting of halide, O—SO4—R7 wherein R7 is Ci to C6 alkyl, or O—SO2-Rs wherein Rs is phenyl, tolyl, methyl or trifluoromethyl; to form a compound of formula (2?) wherein Pg is H or an OH protecting group, Ri is alkyl, aryl, or arylalkyl; and removing the Ri group and where present removing the OH protecting group; or (B) reducing a compound of formula 4?, a compound of formula 4? or a mixture thereof: (4?), (4?) wherein Pg is H or an OH
    Type: Application
    Filed: August 6, 2020
    Publication date: October 27, 2022
    Inventors: Parven Kumar Luthra, Suhail Ahmad, Neval Kishor, Miteshgir Kanchangir Goswami, Alok Singh, Chandrasekhar Sinha, Syed Aziz Imam Quadri, Prashant Shankar Joshi, Sadanand Hardeo Maurya
  • Process for the preparation of intermediates useful in the synthesis of Eluxadoline
    Patent number: 10472329
    Abstract: The invention relates to an improved process for preparing [(S)-1-(4-phenyl-1-H-imidazol-2-yl)-ethyl]-amine. The process involves formation of the novel intermediate crystalline compound [(S)-1-(4-phenyl-1-H-imidazol-2-yl)-ethyl]-carbamic acid tert-butyl ester oxalate.
    Type: Grant
    Filed: February 22, 2016
    Date of Patent: November 12, 2019
    Assignee: Allergan Holdings Unlimited Company
    Inventors: Parven Kumar Luthra, Chandrasekhar Sinha, Syed Aziz Imam Quadri, Tonmoy Chitta Das
  • PROCESS FOR THE PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ELUXADOLINE
    Publication number: 20180029994
    Abstract: The invention relates to an improved process for preparing [(S)-1-(4-phenyl-1-H-imidazol-2-yl)-ethyl]-amine. The process involves formation of the novel intermediate crystalline compound [(S)-1-(4-phenyl-1-H-imidazol-2-yl)-ethyl]-carbamic acid tert-butyl ester oxalate.
    Type: Application
    Filed: February 22, 2016
    Publication date: February 1, 2018
    Inventors: Parven Kumar LUTHRA, Chandrasekhar SINHA, Syed Aziz Imam QUADRI, Tonmoy Chitta DAS