Patents by Inventor Syed F. A. Hossainy

Syed F. A. Hossainy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140186417
    Abstract: An aliphatic polyester polymer for stent coating is described.
    Type: Application
    Filed: February 20, 2014
    Publication date: July 3, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: O. Mikael Trollsas, Lothar W. Kleiner, Syed F.A. Hossainy
  • Publication number: 20140178454
    Abstract: The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
    Type: Application
    Filed: December 17, 2013
    Publication date: June 26, 2014
    Inventors: Florencia Lim, Mikael O. Trollsas, Syed F.A. Hossainy, Stephen D. Pacetti
  • Publication number: 20140161862
    Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.
    Type: Application
    Filed: February 17, 2014
    Publication date: June 12, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Syed F.A. Hossainy, Mikael Trollsas, Stephen D. Pacetti
  • Publication number: 20140154400
    Abstract: Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
    Type: Application
    Filed: January 14, 2014
    Publication date: June 5, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yung-Ming Chen, Jason Van Sciver, Syed F.A. Hossainy, Stephen D. Pacetti
  • Publication number: 20140127278
    Abstract: The present invention relates to the treatment of vascular disease in a diabetic patient using a drug-eluting implantable medical device that releases everolimus from three distinctly loaded drug reservoir layers wherein at least one of the layers comprises at least 200 ?g/cm2 of everolimus and further wherein the everolimus is the only therapeutic agent in the layers or the layers or any combination thereof further comprise an anti-inflammatory agent or an RGD peptide or both.
    Type: Application
    Filed: November 2, 2012
    Publication date: May 8, 2014
    Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.
    Inventor: Syed F.A. Hossainy
  • Patent number: 8715707
    Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from a coating layer for medical devices comprising a polymer matrix and one or more active agents. The methods comprise exposing a wet or dry coating to a freeze-thaw cycle. The coating layer can be used for controlled delivery of an active agent or a combination of active agents.
    Type: Grant
    Filed: May 25, 2012
    Date of Patent: May 6, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Gordon S. Stewart, Benjamyn Serna, Lothar W. Kleiner
  • Patent number: 8709473
    Abstract: This invention relates to the targeted delivery of hydrophobic drugs or combinations of hydrophobic drugs with photodynamic therapy agents to vascular lesions by complexation of the drugs to blood serum lipoproteins, which have an affinity for and accumulate in such vascular lesions.
    Type: Grant
    Filed: January 28, 2009
    Date of Patent: April 29, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Dariush Davalian, John Stankus, Yuet Mei Khong, O. Mikael Trollsas, Syed F. A. Hossainy
  • Patent number: 8685433
    Abstract: The present invention provides an absorbable coating for an implantable device and the methods of making and using the same.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: April 1, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Lothar W. Kleiner, Syed F. A. Hossainy, Mikael Trollsas, Stephen D. Pacetti
  • Patent number: 8685430
    Abstract: A aliphatic polyester polymer for stent coating is described.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: April 1, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael Trollsas, Lothar W. Kleiner, Syed F. A. Hossainy
  • Patent number: 8685428
    Abstract: A method of making a therapeutic composition, as well as the therapeutic composition so made, is disclosed. The method comprises mixing a hydrophobic drug with an aqueous buffer solution and adding a surfactant to the aqueous buffer solution to form the therapeutic composition. A implantable medical device with the therapeutic composition and a method of making a coating for an implantable medical device containing the therapeutic composition is also disclosed.
    Type: Grant
    Filed: November 20, 2006
    Date of Patent: April 1, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Gina Zhang, Syed F. A. Hossainy, Eugene Park, Qi Wang
  • Patent number: 8661630
    Abstract: The present invention provides a coating comprising a reservoir layer comprising a semi-crystalline polymer and a primer layer comprising an amorphous polymer on an implantable device and methods of making and using the same.
    Type: Grant
    Filed: May 21, 2008
    Date of Patent: March 4, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Florencia Lim, Mikael Trollsas, Syed F. A. Hossainy, Stephen D. Pacetti
  • Patent number: 8652501
    Abstract: Primer coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The primer coatings can include a material with a high content of hydrogen bonding groups, such as some types of epoxy polymers and melamine formaldehydes. Coatings subsequently disposed over the primer coating can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: February 18, 2014
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evgenia Mandrusov
  • Patent number: 8647655
    Abstract: A composition comprising a structural component comprising linear acrylic homopolymers or linear acrylic copolymers and a biobeneficial component comprising copolymers having an acrylate moiety and a biobeneficial moiety is disclosed. A medical article comprising the composition in the coating thereof and a method of fabricating the medical article are also disclosed.
    Type: Grant
    Filed: June 18, 2010
    Date of Patent: February 11, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventor: Syed F. A. Hossainy
  • Publication number: 20140038907
    Abstract: The present application teaches a coating having a biologically compatible compound conjugated to, or blended with, a polymer, wherein the polymer includes at least one olefin-derived unit and at least one unit derived from a vinyl alcohol, an allyl alcohol, or derivatives thereof.
    Type: Application
    Filed: October 2, 2013
    Publication date: February 6, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Eugene T. Michal, Syed F.A. Hossainy, Ashok Shah
  • Publication number: 20140037832
    Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
    Type: Application
    Filed: October 15, 2013
    Publication date: February 6, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Florian N. Ludwig, Syed F.A. Hossainy, Srinivasan Sridharan, Carol Lee
  • Publication number: 20140037831
    Abstract: Methods are disclosed for controlling the morphology and the release-rate of active agent from coating layers for medical devices comprising a polymer matrix and one or more active agents. The methods comprise fixing the morphology or phase distribution of the active agent prior to removing solvent from the coating composition. The coating layers can be used for controlled the delivery of an active agent or a combination of active agents.
    Type: Application
    Filed: October 10, 2013
    Publication date: February 6, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Florian N. Ludwig, Syed F.A. Hossainy, Srinivasan Sridharan, Carol Lee
  • Patent number: 8642062
    Abstract: The present invention provides an implantable device having a coating including a slow dissolving polymer or material and the methods of making and using the same.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: February 4, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Mikael O. Trollsas, Michael H. Ngo, David J. Sherman, Syed F. A. Hossainy
  • Patent number: 8641666
    Abstract: Catheters with laminar flow bioactive agent delivery properties and methods of using for treating or preventing vascular disease are disclosed.
    Type: Grant
    Filed: May 16, 2007
    Date of Patent: February 4, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Fozan O. El-Nounou, Florian N. Ludwig, Syed F. A. Hossainy, Paul Consigny
  • Patent number: 8632845
    Abstract: Various embodiments of methods for coating stents are described herein. Applying a composition including polymer component and solvent to a stent substrate followed by exposing the polymer component to a temperature equal to or greater than a Tg of the polymer component is disclosed. Repeating the applying and exposing one or more times to form a coating with the result that the solvent content of the coating after the final exposing step is at a level suitable for a finished stent is further disclosed.
    Type: Grant
    Filed: April 23, 2010
    Date of Patent: January 21, 2014
    Assignee: Abbott Cardiovascular Systems Inc.
    Inventors: Yung-Ming Chen, Jason Van Sciver, Syed F. A. Hossainy, Stephen D. Pacetti
  • Publication number: 20140018907
    Abstract: Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 16, 2014
    Applicant: Abbott Cardiovascular Systems Inc.
    Inventors: Yunbing WANG, David C. GALE, Syed F.A. HOSSAINY