Abstract: A modified health diagnostic compact disc (HDCD) comprising (a) a protective layer; (b) a reflective layer; (c) a dye layer (d) a polycarbonate layer; and (e) a micro fluidic layer. In a certain aspect, the polycarbonate layer of the HDCD contains a data layer. The micro fluidic layer of the HDCD is composed of polydimethylsiloxane (PDMS). The micro fluidic layer of the HDCD contains one or more donut-shaped trenches. The micro fluidic layer of the HDCD is associated with conjugated microparticles in solution. The HDCD further comprises integrated microneedles. The modified health diagnostic compact disc can be used by methods of the invention to identify and/or measure the presence of biologic cells utilizing a standard computer compact disk drive.