Patents by Inventor Syed Z. Salahuddin

Syed Z. Salahuddin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Preparation of replicating macrophages and use in diagnosis and therapy
    Publication number: 20090117086
    Abstract: Provided are methods for replicating macrophages in vitro and cell culture compositions comprising replicating macrophages. Also provided are methods for preparing replicating Kupffer cells from human liver. Further provided are methods for enhancing or extending immune function in an individual suffering from a deficiency relating to a reduced number of functional macrophages in a tissue or organ by administering a therapeutically effective amount of a replicating macrophages obtained by the methods of the invention.
    Type: Application
    Filed: July 18, 2008
    Publication date: May 7, 2009
    Inventor: Syed Z. Salahuddin
  • Preparation of replicating macrophages and use in diagnosis and therapy
    Publication number: 20020127717
    Abstract: Provided are methods for replicationg macrophages in vitro and cell culture composition comprising relicating macrophages. Also provided are methods for preparing replicating Kupffer cells from human liver. Further provided are methods for enhancing or extending immune function in an individual suffering from a deficiency relating to a reduced number of functional macrophages in a tissue or organ by administering a therapeutically effective amount of a replicating macrophages obtained by the methods of the invention.
    Type: Application
    Filed: November 16, 2001
    Publication date: September 12, 2002
    Inventor: Syed Z. Salahuddin
  • Human herpesvirus-6(HHV-6)Isolution and Products
    Patent number: 5604093
    Abstract: A new human B lymphotropic virus, also designated human herpesvirus-6, has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. Various utilities of the new virus and products derived therefrom have been described.
    Type: Grant
    Filed: February 22, 1995
    Date of Patent: February 18, 1997
    Assignee: The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services
    Inventors: Syed Z. Salahuddin, Dharam V. Ablashi, Steven F. Josephs, Carl W. Saxinger, Flossie Wong-Staal, Robert C. Gallo
  • Method for treating Kaposi's sarcoma and blocking or inhibiting vascular permeability
    Patent number: 5518999
    Abstract: The present invention is directed to a method for arresting or inhibiting the growth of cells in Kaposi's Sarcoma lesions and a method for arresting or inhibiting the growth of the Kaposi's Sarcoma lesions, said methods comprising contacting the cells in the lesions with an effective amount of SP-PG, a naturally occurring sulfated polysaccharide-peptidoglycan produced by a specific species of the bacterium Arthrobacter, AT-25. The invention is also directed to blocking or inhibiting the activity of cellular vascular permeability factor(s), which comprises contacting vascular cells with an effective amount of SP-PG. In one embodiment, there is provided a method for blocking or inhibiting increased vascular permeability (and resulting edema) in diseases and disorders in which the increased vascular permeability contributes to the pathology, for example, in Kaposi's Sarcoma, tumorigenesis, inflammation, diabetic retinopathy, etc.
    Type: Grant
    Filed: November 9, 1994
    Date of Patent: May 21, 1996
    Assignees: The United States of America as represented by the Secretary of the Department of Health and Human Services, Daiichi Pharmaceutical Co., Ltd.
    Inventors: Shuji Nakamura, Robert C. Gallo, Yasuaki Osada, Shinsaku Sakurada, Noriko G. Tanaka, Syed Z. Salahuddin
  • Kaposi's sarcoma endothelial cells and growth factor
    Patent number: 5106731
    Abstract: The present invention relates to a growth factor found in HTLV-II conditioned media and to compositions containing same. The growth factor of the present invention supports the growth of Kaposi's sarcoma endothelial-like cells. The factor has a molecular weight of 30K to 35K in monomeric form and a molecular weight of about 70K in dimeric form.
    Type: Grant
    Filed: October 21, 1988
    Date of Patent: April 21, 1992
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Syed Z. Salahuddin, Shuji Nakamura, Robert C. Gallo
  • Antibodies against human herpes virus-6(HHV-6) and method of use
    Patent number: RE38824
    Abstract: A new human B lymphotropic virus, also designated human herpesvirus-6, has been isolated. DNA, molecular clones, antigenic viral proteins and antibodies having specificity to the new virus have been prepared. Various utilities of the new virus and products derived therefrom have been described.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: October 11, 2005
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Syed Z. Salahuddin, Dharam V. Ablashi, Steven F. Josephs, Carl W. Saxinger, Flossie Wong-Staal, Robert C. Gallo