Patents by Inventor Sylvie Sim

Sylvie Sim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Generation of nitric oxide in situ at substrate/blood interfaces and reproducible nitric oxide sensor for detecting nitrosothiols
    Publication number: 20040224868
    Abstract: A material includes a surface and a reactive agent that is located at the surface of the material, covalently attached to a backbone of the material, and/or located within the material. The reactive agent has nitrite reductase activity, nitrate reductase activity, and/or nitrosothiol reductase activity. The reactive agent also converts at least one of nitrites, nitrates and nitrosothiols to nitric oxide when in contact with blood. A reproducible nitrosothiol sensor is also disclosed.
    Type: Application
    Filed: March 5, 2004
    Publication date: November 11, 2004
    Inventors: Mark E. Meyerhoff, Melissa M. Reynolds, Bong K. Oh, Wansik Cha, Megan Frost, Sangyeul Hwang, Sylvie Sim, Yiduo Wu