Abstract: This invention relates to in vitro cell culture employing a fibrin network in a flexible gas permeable container. Specifically, the invention is directed to a cell culture container comprising a flexible, gas permeable material with fibrin matrix which is conducive to the culture of anchorage dependent cells, and the container is suitable for use in closed system in vitro cell culture. The gas permeability of the container is sufficient to permit cellular respiration.

Abstract: A belt grinding machine for forming cutting edges of complex geometry on surgical instruments includes a fixture for holding an instrument with a site thereon in a position for grinding a surface at the site on the instrument, a grinding assembly having a grinding belt with a planar span for grinding the surface at the site on the instrument, an oscillation producing mechanism for oscillating the instrument relative to the grinding belt so as to reciprocally translate the site on the instrument parallel and relative to the planar span of the grinding belt concurrently with grinding the surface at the site on the instrument, a translation producing mechanism for selectively translating the grinding assembly and thus the planar span of the grinding belt toward and away from the site on the instrument to permit receiving and setting up of the instrument in the instrument holding fixture and to place the instrument in a position for the planar span of the grinding belt to grind the surface at the site on the inst

Abstract: A gripper member comprises an openable and closable pair of handles interconnected by a hinge member. Each handle defines, adjacent its hinge member, an arcuate recess positioned to face the corresponding recess of the other handle and defining gripping projections therein. A wall member is positioned longitudinally on each handle to cross each arcuate recess, both wall members being positioned at the same side of their respective recesses. Accordingly, a plastic tube may be surrounded and gripped in the arcuate recesses of the handles for rotational retention thereof as a connector member is inserted into or withdrawn from the tube. At the same time, the wall members pinch the tube into closed, sealed relation with the handles in closed position.