Abstract: Jet pump clamps fit to modified jet pump assemblies at the riser pipe-restrainer bracket junction. The clamp can secure the restrainer bracket and riser pipe, relieving any welds between the same stress in the same, while preventing the restrainer bracket from moving. The clamp may include multiple members on either side of the restrainer bracket that fit into surfaces of the riser pipe. When these members are drawn together through clamping action, the underlying riser pipe is compressed. Similarly, vertically-adjustable members may seat into and/or through the restrainer bracket to hold the bracket steady. Jet pump assemblies may be prepared by forming grooves in the riser pipe and hole(s) in the restrainer bracket(s) and spherical indentations about the same. Clamps may then be installed on the grooves and through the hole(s) at installation or during a maintenance outage in a commercial nuclear power plant.

Abstract: Systems and methods to prevent leakage of an intestine and/or provide support to an intestine. The systems can carry the leakage protection device on an external surface for delivery or carry the leakage protection device internally within a lumen. The device is delivered into the intestine portions to protect a site where a defect is repaired such as at an anastomotic site.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: A neuromodulation therapy is delivered via at least one electrode implanted subcutaneously and superficially to a fascia layer superficial to a nerve of a patient. In one example, an implantable medical device is deployed along a superficial surface of a deep fascia tissue layer superficial to a nerve of a patient. Electrical stimulation energy is delivered to the nerve through the deep fascia tissue layer via implantable medical device electrodes.

Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.

Abstract: The present invention relates to the application of a force to enhance the performance of an electrochemical cell. The force may comprise, in some instances, an anisotropic force with a component normal to an active surface of the anode of the electrochemical cell. In the embodiments described herein, electrochemical cells (e.g., rechargeable batteries) may undergo a charge/discharge cycle involving deposition of metal (e.g., lithium metal) on a surface of the anode upon charging and reaction of the metal on the anode surface, wherein the metal diffuses from the anode surface, upon discharging. The uniformity with which the metal is deposited on the anode may affect cell performance. For example, when lithium metal is redeposited on an anode, it may, in some cases, deposit unevenly forming a rough surface. The roughened surface may increase the amount of lithium metal available for undesired chemical reactions which may result in decreased cycling lifetime and/or poor cell performance.

Abstract: Method and device to prevent leakage of an intestine during surgery. The device is a tubular straw like device formed as one piece and having a first end opening, a second end opening and a lumen extending through an entire length of the device. The device can include an enlarged diameter rim to provide a radial force against the intestine. The device is placed at an anastomotic site of two intestine portions and attached by adhesive. The device can be used to close off perforations of body lumens.

Abstract: Method and device to prevent leakage of an intestine during surgery. The device is a tubular straw like device formed as one piece and having a first end opening, a second end opening and a lumen extending through an entire length of the device. The device can include an enlarged diameter rim to provide a radial force against the intestine. The device is placed at an anastomotic site of two intestine portions and attached by adhesive. The device can be used to close off perforations of body lumens.

Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.

Abstract: A method for recommending a computer hardware configuration, including: receiving, by a processor, a machine-readable specification of a computing task; extracting, by the processor, a plurality of features from the machine-readable specification of the computing task; supplying, by the processor, the plurality of features to a reinforcement learning model to generate a proposed computer hardware configuration to execute the computing task; and providing, by the processor, the proposed computer hardware configuration to a user.

Abstract: A knitted component includes a first side extending along a perimeter of the knitted member to define a lower edge of the knitted member and a pair of heel edges that can be joined together, and a second side that defines a throat region and/or a collar region. A plurality of rows of the knitted component extend between the first side and the second side, and a continuous strand is integrated with the knitted component to form a plurality of strand segments that extend within respective ones of the plurality of rows of the knitted component between the first side and the second side.

Abstract: A soil sampler assembly includes a utility vehicle and a soil sampler module coupled to the utility vehicle. The utility vehicle includes a cab, and the soil sampler module is configured to deposit a soil sample in the cab. For example, the soil sampler assembly includes a conveyor system configured to convey the soil sample to the cab. The soil sampler assembly further includes a sampler arm assembly. The sampler arm assembly includes a power cylinder, a guide cylinder, a transfer block, and a probe. The probe is coupled to the soil sampler module and defines a longitudinal interior channel configured to receive the soil sample and release the soil sample for collection. The probe is rotatable from a first orientation facing the ground to a second orientation where the probe is facing opposite the ground for releasing the soil sample onto the conveyor system.

Abstract: Disclosed herein are Notch transcriptional activation complex kinase (“NACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (la) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.

Abstract: The disclosed technology is generally directed to the conversion of text to tables. In one example of the technology, input text that includes at least three rows is received. A plurality of characteristics of the input text is determined. Each characteristic of the plurality of characteristics is associated with a uniformity between the rows of the input text. The plurality of characteristics includes at least one characteristic that is associated with a delimiter count. A determination is made as to whether the input text is suitable for conversion to table based on the plurality of characteristics. Upon determining that the input text is suitable for conversion to a table, a machine learning model is used to convert the input text into a table.

Abstract: Disclosed herein are Notch transcriptional activation complex kinase (“MACK”) inhibitors, and methods for their use in treating or preventing diseases, such as cancer. The inhibitors described herein include compounds of Formula (Ia) and pharmaceutically acceptable salts thereof: wherein the substituents are as described.

Abstract: A conductive human interface has a fabric layer with an interior surface and an exterior surface. A soft coating overlies the interior surface of the fabric layer. An electrode or sensor is included to connect with a user. A conductive path connects the electrode or sensor with an electrical connector which, in turn connects with a prosthetic or other assistive device. The conductive path includes a conductor having a section overlying the fabric layer. The overlying section of the conductor can be cord of conductive thread. A nonconductive support thread can extend through the fabric layer from the exterior surface to the interior surface, and further around the conductor to secure the overlying section of the conductor to the fabric layer.

Abstract: A conductive human interface has a fabric layer with an interior surface and an exterior surface. A soft coating overlies the interior surface of the fabric layer. An electrode or sensor is included to connect with a residual limb. A conductive path connects the electrode or sensor with an electrical connector which, in turn connects with a prosthetic or other assistive device. The conductive path includes a conductor having a section overlying the fabric layer. The overlying section of the conductor can be cord of conductive thread. A nonconductive support thread can extend through the fabric layer from the exterior surface to the interior surface, and further around the conductor to secure the overlying section of the conductor to the fabric layer.

Abstract: Prosthetic socket sealing systems and methods of use. Embodiments of the present invention include various combinations of sealing elements that are associated with a rigid prosthetic socket and act to seal the socket interior against air intrusion or escape via the open proximal end thereof. The socket interior may thus be evacuated for purposes of vacuum suspension or otherwise.

Abstract: Provided are apparatus and systems for performing a swing adsorption process. This swing adsorption process may involve passing streams through adsorbent bed units to remove contaminants, such as water, from the stream. As part of the process, the adsorbent bed unit may provide access to the adsorbent material within the adsorbent bed unit without having to remove one or more of valves, conduits and manifolds.

Abstract: An electrode is supported on a prosthetic liner to communicate electrically with a residual limb. A housing is fixed to the liner, and is receivable in a socket in an installed position. A processor is installed in the housing in communication with the electrode. Electrical signal contacts are exposed at a distal end of the housing for contacting electrical signal contacts in the socket. The housing defines a ground current path that communicates with a ground contact in the socket.