Patents by Inventor Tadahiro Matsuno
Tadahiro Matsuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9551661Abstract: An assay chip includes fluidic-channel member composed of a light-transmissive lower member and an upper member, forming a fluidic-channel therebetween, and a cover member fitted with the fluidic-channel member from the upper-member-side thereof. An inlet for injecting a sample solution into the fluidic-channel and a suction opening for sucking, from the downstream side, the injected sample solution, both communicating with the fluidic-channel, are formed on the upper surface of the upper member. A pot for carrying out predetermined pre-processing on the sample solution, a pot for first-reaction processing to bind a photoresponsive labeling substance to an analyte in the sample solution, an inlet insertion-hole for inserting the inlet, and a suction-opening insertion-hole for inserting the suction opening are linearly arranged on the upper surface of the cover member.Type: GrantFiled: June 6, 2013Date of Patent: January 24, 2017Assignee: FUJIFILM CorporationInventors: Toshihito Kimura, Akihiro Komatsu, Toshihiro Mori, Hideyuki Karaki, Nobuhiko Fujiwara, Kouta Katou, Tadahiro Matsuno
-
Patent number: 8912010Abstract: Provided are a base plate and a method for thyroxine immunoassay, which are capable of decreasing the signal change rate caused by temperature change in a high-sensitivity immunoassay method for thyroxine. A base plate for thyroxine immunoassay which has a conjugate of thyroxine or a derivative thereof and albumin immobilized thereon, and in which the ratio of the molecule number of thyroxine or a derivative thereof to the molecule number of albumin in the immobilized conjugate, is disclosed.Type: GrantFiled: September 11, 2012Date of Patent: December 16, 2014Assignee: FUJIFILM CorporationInventors: Noriyuki Kasagi, Junichi Katada, Tadahiro Matsuno
-
Publication number: 20130266480Abstract: An assay chip includes fluidic-channel member composed of a light-transmissive lower member and an upper member, forming a fluidic-channel therebetween, and a cover member fitted with the fluidic-channel member from the upper-member-side thereof. An inlet for injecting a sample solution into the fluidic-channel and a suction opening for sucking, from the downstream side, the injected sample solution, both communicating with the fluidic-channel, are formed on the upper surface of the upper member. A pot for carrying out predetermined pre-processing on the sample solution, a pot for first-reaction processing to bind a photoresponsive labeling substance to an analyte in the sample solution, an inlet insertion-hole for inserting the inlet, and a suction-opening insertion-hole for inserting the suction opening are linearly arranged on the upper surface of the cover member.Type: ApplicationFiled: June 6, 2013Publication date: October 10, 2013Inventors: Toshihito KIMURA, Akihiro KOMATSU, Toshihiro MORI, Hideyuki KARAKI, Nobuhiko FUJIWARA, Kouta KATOU, Tadahiro MATSUNO
-
Patent number: 8524864Abstract: It is an object of the present invention to provide a method for producing a conjugate of thyroxine and albumin with higher purity. The present invention provides a method for producing a conjugate of thyroxine and albumin which comprises: step (a) of converting a carboxyl group in thyroxine having a carboxyl group to be linked to albumin into an active ester and allowing the thyroxine to react with albumin, so as to prepare a conjugate of thyroxine and albumin; and step (b) of purifying the conjugate with the use of an acidic mixed aqueous solvent in which the thyroxine having a carboxyl group to be linked to albumin is dissolved but albumin is not precipitated.Type: GrantFiled: August 19, 2011Date of Patent: September 3, 2013Assignee: FUJIFILM CorporationInventors: Noriyuki Kasagi, Tadahiro Matsuno
-
Publication number: 20130078737Abstract: Provided are a base plate and a method for thyroxine immunoassay, which are capable of decreasing the signal change rate caused by temperature change in a high-sensitivity immunoassay method for thyroxine. A base plate for thyroxine immunoassay which has a conjugate of thyroxine or a derivative thereof and albumin immobilized thereon, and in which the ratio of the molecule number of thyroxine or a derivative thereof to the molecule number of albumin in the immobilized conjugate, is disclosed.Type: ApplicationFiled: September 11, 2012Publication date: March 28, 2013Applicant: FUJIFILM CORPORATIONInventors: Noriyuki KASAGI, Junichi KATADA, Tadahiro MATSUNO
-
Publication number: 20120046447Abstract: It is an object of the present invention to provide a method for producing a conjugate of thyroxine and albumin with higher purity. The present invention provides a method for producing a conjugate of thyroxine and albumin which comprises: step (a) of converting a carboxyl group in thyroxine having a carboxyl group to be linked to albumin into an active ester and allowing the thyroxine to react with albumin, so as to prepare a conjugate of thyroxine and albumin; and step (b) of purifying the conjugate with the use of an acidic mixed aqueous solvent in which the thyroxine having a carboxyl group to be linked to albumin is dissolved but albumin is not precipitated.Type: ApplicationFiled: August 19, 2011Publication date: February 23, 2012Inventors: Noriyuki KASAGI, Tadahiro Matsuno
-
Patent number: 8110403Abstract: It is an object of the present invention to provide an immunoassay method which is capable of simultaneous quantification of a plurality of test substances under a same analysis condition, through adjustment of the measurement sensitivity/range by simply varying the size of particles for use as labels, without changing the spectra of these particles.Type: GrantFiled: February 11, 2009Date of Patent: February 7, 2012Assignee: Fujifilm CorporationInventors: Tadahiro Matsuno, Kentaro Nakamura
-
Publication number: 20100075435Abstract: A means for conveniently and accurately measuring thyroxine or thyronine present in the blood or the like is provided: a compound represented by general formula (I) below: wherein L represents a linear or branched-chain linker having 5 to 50 total atoms; X represents one or more thyroxines, thyronines, or residues of derivatives thereof, bound to the main chain and/or side chain of the linker represented by L, a conjugate in the form of the above compound bonded to an avidin protein, and an aqueous dispersion including a microparticles the surface of which is modified with the above conjugate.Type: ApplicationFiled: July 27, 2009Publication date: March 25, 2010Inventors: Noriyuki KASAGI, Tadahiro Matsuno
-
Publication number: 20090203151Abstract: It is an object of the present invention to provide an immunoassay method which is capable of simultaneous quantification of a plurality of test substances under a same analysis condition, through adjustment of the measurement sensitivity/range by simply varying the size of particles for use as labels, without changing the spectra of these particles.Type: ApplicationFiled: February 11, 2009Publication date: August 13, 2009Inventors: Tadahiro MATSUNO, Kentaro Nakamura
-
Publication number: 20080145869Abstract: The present invention provides a method for immunoassaying an object to be analyzed including: causing to act, on a specimen or a sample including the specimen, a first protein (Y), which can specifically recognize the object to be analyzed in the specimen and is modified by a labeling substance, so as to form a complex including the object to be analyzed and Y; and measuring the labeling substance contained in the complex or the labeling substance contained in the free protein (Y), wherein the measurement of the labeling substance is performed by a chemiluminescent method which includes sensing the light generated by chemiluminescence using a photothermographic material including at least an organic silver salt, a reducing agent for silver ions and a photosensitive silver halide to form a latent image, and making the latent image visible by thermal development. An easy, quick, and highly precise immunoassay method is provided.Type: ApplicationFiled: December 10, 2007Publication date: June 19, 2008Applicant: FUJIFILM CORPORATIONInventors: Katsuhisa Ohzeki, Tadahiro Matsuno