Patents by Inventor Tadao Kojima
Tadao Kojima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20060215266Abstract: An optical low-pass filter includes: two birefringent plates; a phase plate made of a polymer film and bonded between the two birefringent plates through an adhesive layer or a tacky layer; and a sealing portion provided over an entire periphery of an external periphery surface of the optical low-pass filter.Type: ApplicationFiled: March 27, 2006Publication date: September 28, 2006Inventors: Takehiko Uehara, Kazuhiro Hara, Tadao Kojima
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Publication number: 20060012889Abstract: A resin composition for use in a hybrid lens containing a radical polymerizable monomer and a silane coupling agent. A specified di(meth)acrylate compound and a specified mono(meth)acrylate compound are used preferably as the radical polymerizable monomer. A hybrid lens molding die in which a glass lens base material and a glass mold of transferring an aspherical shape are opposed to each other is used, a resin composition for use in the hybrid lens is filled between them and UV-rays are irradiated from both sides of the glass lens base material and the glass mold to manufacture a hybrid lens in which the resin layer is bonded on the glass lens base material. A high performance hybrid lens having a resin layer of large thickness, with a large localized thickness and capable of increasing the aspherical quantity can be manufactured by the method.Type: ApplicationFiled: April 20, 2004Publication date: January 19, 2006Inventors: Tadao Kojima, Akihiro Shimizu, Akira Komatsu
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Patent number: 5708049Abstract: A contact lens colored with a poly(meth)acrylate-combined metallophthalocyanine compound represented by the following formula (I): ##STR1## wherein M represents a metal atom to which phthalocyanine can coordinate, R represents a halogen atom, m is an integer of 0 to 4, R.sup.1 represents a hydrogen atom or a methyl group, and A represents a hydrogen atom, a C.sub.1-12 alkyl group, a hydroxyC.sub.1-12 alkyl group or a glycerol group. The colored contact lens has sufficiently high fastness, so that the lens undergoes neither color change nor color fading even when it is sterilized by boiling.Type: GrantFiled: February 7, 1996Date of Patent: January 13, 1998Assignee: Seiko Epson CorporationInventors: Hiroshi Katagiri, Tadao Kojima, Youichi Ushiyama
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Patent number: 5616715Abstract: A process is provided for producing diastereoisomer A or a pharmaceutically acceptable acid addition salt of 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl) ester 5-methyl ester which comprises subjecting a mixture of diastereoisomers A and B of 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl) ester 5-methyl ester to column chromatography using silica gel as a carrier and a mixture of ethyl acetate and acetic acid as an eluant, and then separating the acetate of diastereoisomer A from the eluate, or treating the acetate with a base, or further treating the resulting diastereoisomer A with a pharmaceutically acceptable acid.Type: GrantFiled: June 19, 1995Date of Patent: April 1, 1997Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Kazuharu Tamazawa, Tadao Kojima, Hideki Arima, Yukiyasu Murakami, Yasuo Isomura, Minoru Okada, Toichi Takenaka, Kiyoshi Takanobu
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Patent number: 5520910Abstract: An antimicrobial polymer obtained by homo- or copolymerizing a phosphonium salt type vinyl monomer, such as 2-(methacrylic acid) ethyltri-n-octylphosphonium chloride, and a contact lens and an article for its care mainly comprising an antimicrobial resin obtained by copolymerizing a polymerizable monomer and a phosphonium salt type vinyl monomer are disclosed. The antimicrobial polymer has a broad antimicrobial spectrum and produces a sufficient antimicrobial effect after a short contact time. The contact lens and article for its care are hardly effected by contamination with microorganisms while retaining excellent optical performance and processability.Type: GrantFiled: March 13, 1995Date of Patent: May 28, 1996Assignees: Nippon Chemical Industrial, Seiko Epson CorporationInventors: Kazukichi Hashimoto, Yoshiko Inaba, Seiji Shimura, Takao Mogami, Tadao Kojima, Yoichi Ushiyama
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Patent number: 5463064Abstract: A dextro-rotatory optical isomer of diastereoisomer A of (.+-.)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzylpyrrolidin-3-yl)ester 5-methyl ester is provided having the formula ##STR1## and wherein the melting point of the hydrochloride of the dextro-rotatory optical isomer is 223.degree. to 230.degree. C. (decomp.), or a pharmaceutically acceptable acid addition salt thereof.Type: GrantFiled: May 5, 1994Date of Patent: October 31, 1995Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Kazuharu Tamazawa, Tadao Kojima, Hideki Arima, Yukiyasu Murakami, Yasuo Isomura, Minoru Okada, Kiyoshi Takanobu, Toichi Takenaka
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Patent number: 5364872Abstract: The diastereoisomer A of a dihydropyridine-3,5-dicarboxylic acid ester derivative is provided as well as its pharmaceutically acceptable acid addition salts. The invention further discloses a process for producing the compounds and their use as medicaments in imparting vasodilating activity.Type: GrantFiled: January 23, 1992Date of Patent: November 15, 1994Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Kazuharu Tamazawa, Tadao Kojima, Hideki Arima, Yukiyasu Murakami, Yasuo Isomura, Minoru Okada, Toichi Takenaka, Kiyoshi Takanobu
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Patent number: 4942242Abstract: Thiazolyl phenoxy derivatives are provided as well as pharmaceutical compositions containing such derivatives. The compositions are useful for lowering lipid activity in a subject and accordingly useful for reducing cholesterol and triglycerides.Type: GrantFiled: October 21, 1988Date of Patent: July 17, 1990Inventors: Tadao Kojima, Shunji Kageyama, Minoru Okada, Isao Ohata, Noboru Sato
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Patent number: 4798838Abstract: The present invention relates to novel phenoxy derivatives represented by the formula (I): ##STR1## wherein: A is an imidazolyl group, a pyridyl group, a pyridyloxy group, an oxo-substituted chromenyloxy group, a lower alkyl group, an amino group which may be substituted with a phenyl group or a lower alkyl group, or a carbamoyl group substituted with a cyclohexylamino group or an imidazolylalkyl group;B is a single bond, a thiazolyl group which may be substituted with a lower alkyl group, a group represented by the formula: --(CH.sub.2).sub.n --O--, --(CH.sub.2).sub.n CONH(CH.sub.2).sub.k -- or --(CH.sub.2).sub.n --N(R.sup.4)-- wherein k is 0 or an integer of 1 to 5, n is an integer of 1 to 6 and R.sup.4 is hydrogen or a lower alkyl group;m is 0 or an integer of 1 to 6;R.sup.1 is a hydroxyl group, an amino group or a lower alkoxy group;R.sup.2 and R.sup.3 which may be the same or different, represent a hydrogen atom or a lower alkyl group hereafter the same:and salts thereof.Type: GrantFiled: September 30, 1986Date of Patent: January 17, 1989Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Tadao Kojima, Shunji Kageyama, Minoru Okada, Isao Ohata, Noboru Sato
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Patent number: 4795753Abstract: The present invention relates to novel phenoxy derivatives represented by the formula (I): ##STR1## wherein: A is an imidazolyl group, a pyridyl group, a pyridyloxy group,B is group represented by the formula: --(CH.sub.2).sub.n --O--, --(CH.sub.2).sub.n CONH(CH.sub.2).sub.k -- or --(CH.sub.2).sub.n-N (R.sup.4)-- wherein k is 0 or an integer of 1 to 5, n is an integer of 1 to 6 and R.sup.4 is hydrogen or a lower alkyl group;m is 0 or an integer of 1 to 6;R.sup.1 is a hydroxyl group, an amino group or a lower alkoxy group;R.sup.2 and R.sup.3 which may be the same or different represent, a hydrogen atom or a lower alkyl group hereafter the same, having lipid lowering activity, and salts thereof.Type: GrantFiled: September 30, 1986Date of Patent: January 3, 1989Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Tadao Kojima, Shunji Kageyama, Minoru Okada, Isao Ohata, Noboru Sato
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Patent number: 4794113Abstract: Imidazolyl phenoxy derivatives are provided as well as pharmaceutical compositions containing such derivatives. The compositions useful for lowering lipid activity in a subject and accordingly useful for reducing cholesterol and triglycerides.Type: GrantFiled: January 2, 1987Date of Patent: December 27, 1988Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Tadao Kojima, Shunji Kageyama, Minoru Okada, Isao Ohata, Noboru Sato
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Patent number: 4690932Abstract: Novel coumarin compounds of the formula ##STR1## wherein R.sup.1 represents an imidazolyl group or a pyridyloxy group which may be substituted by lower alkyl group(s); R.sub.2 represents a hydrogen atom or a lower alkyl group; and m represents an integer of 1 to 6; and the salts thereof, which inhibit platelets aggregation.Type: GrantFiled: May 30, 1986Date of Patent: September 1, 1987Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Tadao Kojima, Shunji Kageyama, Minoru Okada, Isao Ohata, Noboru Sato
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Patent number: 4220649Abstract: 1,4-Dihydropyridine-3,5-dicarboxylic acid ester derivatives shown by the formula ##STR1## wherein R represents a lower alkyl group and R' represents a hydrogen atom, a lower alkyl group or an aralkyl group, and the therapeutically non-toxic salts thereof.These compounds possess a vasodilative activity and an antihypertensive activity.Type: GrantFiled: January 31, 1979Date of Patent: September 2, 1980Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Tadao Kojima, Toichi Takenaka
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Patent number: 4210751Abstract: Process for producing 7.beta.-amino-7.alpha.-methoxycephalosporins without the epimerization or formation of the corresponding 7.alpha.-amino-7.beta.-methoxy isomers by deacylating cephalosporin derivatives having 7.beta.-acylamino-7.alpha.-methoxy group.Type: GrantFiled: August 2, 1978Date of Patent: July 1, 1980Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Kazuharu Tamazawa, Takashi Fujikura, Tadao Kojima, Masaru Iwanami
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Patent number: 4109088Abstract: 2-(Indenyloxymethyl) morpholine derivatives are disclosed. These derivatives are excellent in methamphetamine stereotyped increasing and antireserpine activities which are useful as antidepression agents.Type: GrantFiled: February 25, 1977Date of Patent: August 22, 1978Assignee: Yamanouchi Pharmaceutical Co., Ltd.Inventors: Masuo Murakami, Kozo Takahashi, Yuji Kawashima, Tadao Kojima, Kunihiro Niigata, Takashi Fujikura, Yoshihisa Nozaki, Shiro Tachikawa, Shinji Usuda, Soichi Kagami