Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.

Abstract: Methods are described for treating a target tissue with a radioisotope. Some methods include determining a distance between a target tissue and a surface of a matrix material to be positioned adjacent the target tissue and, based on the determined distance, determining an activity to be mixed with the matrix material to obtain a desired activity concentration. Some methods further include mixing the radioisotope with the matrix material. In some embodiments, the matrix material is a bone cement, and the target tissue is a tumor in a bone. The radioisotope may be a beta-emitting radioisotope mixed in the cement at a concentration to form a radioactive cement.

Abstract: To provide a bone graft substitute having an appropriate absorption period in a living body and high osteoconductivity, the bone graft substitute contains a carbonate apatite and an osteoinductive factor, the osteoinductive factor is preferably at least one kind selected from a group including BMP (a bone morphogenetic protein), GDF (a growth differentiation factor), TGF-? (a transformation growth factor), FGF (a fibroblast growth factor), IGF (an insulin-like growth factor), PDGF (a platelet-derived growth factor), BDNF (a brain-derived nerve growth factor), and NGF (a nerve growth factor), and the bone graft substitute has open pores, preferably having a diameter of 50 to 1000 ?m and/or a diameter of 0.001 to 5 ?m, with porosity of 20 to 80%.

Abstract: A block-shaped scaffold for a tissue engineering with improved shape stability and less volume change in water is produce by the steps of approximate-uniformly mixing the particle-shaped material having 100 to 2000 ?m diameter with a solution, where a biodegradable polymer is dissolved with an organic solvent, freezing, drying it to remove the solvent, pulverizing thus obtained intermediate product, dissolving it with a liquid, where the biodegradable polymer is not dissolved, to remove the particle-shaped material taking thus obtained intermediate product into a mold, and pressing and heating it, the scaffold having ununiform and continuous holes occupying 20 to 80% in a cross-section area in a three-dimensional network structure having a small hole structure with 5 to 50 ?m diameter, elastic coefficient being 0.1 to 2.5 MPa, and volume change being 95 to 105% when dipping it in water for 24 hours.

Abstract: To provide a scaffold for tissue engineering which consists of a bioabsorbable polymer material to be absorbed in a biotissue, and holds strength of the whole scaffold while having a porosity proper for culturing cells inside thereof as well, a method for producing the scaffold for tissue engineering includes steps of dissolving a bioabsorbable polymer material with an organic solvent, drying the solution so as to produce a porous bioabsorbable polymer material having a porosity of 50 to 99%, covering the porous bioabsorbable polymer material with a bioabsorbable polymer material having a thickness of 0.01 to 5 mm, pores of 10 to 3000 ?m diameter, a fracture strength of 0.05 to 0.15 MPa, and a volume of 15 to 90% with respect to the whole scaffold.

Abstract: To provide a bone tissue regeneration sheet having a cortical bone tissue layer of 200 ?m or more in thickness, the bone tissue regeneration sheet is produced by seeding chondroblast or stem cells for differentiating to chondrocyte on one side of a porous bioabsorbable polymer sheet, taking the seeded porous body into a culture medium, applying centrifugal force of 100 to 1000 G to the culture medium for a predetermined time so as to aggregate the chondroblast or the stem cells for differentiating to chondrocyte, culturing the aggregated cells in a culture medium not containing serum but containing one or two or more kinds selected from ascorbic acid, an ascorbic acid derivative, and dexamethasone without applying centrifugal force to form a chondrocyte layer having a thickness of 200 ?m or more.

Abstract: For easily seeding cells in its scaffold, a porous cell scaffold is produced by steps of filling a guiding solution with kinematic viscosity being 50 to 450% of that of a culture medium, in a whole continuous small hole structure having hole diameters of 5 to 3200 ?m and an average hole diameter of 50 to 1500 ?m, of a sheet-shaped or block-shaped scaffold having a thickness of 2 mm or more, supplying thereafter a culture medium with cells being suspended to an upper side of the scaffold, sucking the guiding solution from a lower side of the scaffold by low suction force, and entering thereby the culture medium with cells being suspended into the whole small hole structure, where a water absorber such as a filter paper is preferably used for sucking the guiding solution by low suction force.

Abstract: The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be secured, and particularly in the case of cartilage, fixation treatment such as suture can be carried out in the transplantation into affected parts after the culture, and the mechanical strength is provided sustainable for (weighted) compression at the initial stage of transplantation. The present invention relates to a 3-dimensional porous scaffold for tissue regeneration which comprises a structure composed of vertically long-shaped pores having a pore diameter of not less than 10 ?m to not more than 500 ?m and pore length of not less than 20 ?m to not more than 1 cm being juxtaposedly arranged obtained by a production process comprising rapid freeze-drying as a key technology.

Abstract: To provide an organism absorbency tube for regenerating nerve tissue and a production method thereof, where the low cost tube can produce easier than a conventional one, various kinds of the different thickness tubes, inner diameters and outer shapes can be easily formed. The tube produces by drying polymer solvent to form sheet-like organism absorbency polymer material; cylindrically rolling thus material to form an overlapped sheet part; heat or solvent meld sealing at least a portion around an end edge on the outer peripheral side thereof. Or a two layers structure tube produces by freeze-drying polymer solvent to form the material; cylindrically rolling thus material; non-freeze-drying polymer solvent to form the high material; cylindrically wrapping thus material around the freeze-dried polymer material to form the sheet part; and heat or solvent meld sealing at least a portion around an edge on the outer peripheral side thereof.

Abstract: To prevent complication caused by leakage of bone cement injected into the vertebral body, organism damage caused by the leakage of the monomer or a non-cured component from bone cement and decrease of strength caused by insufficient curing of bone cement, in the percutaneous kyphoplasty, a leakage prevention bag for injecting and filling a bone cement is used, wherein the bad is made of a bioabsorbable material having a molecular weight of 5,000 to 500,000 and has a bag having the thickness of 10 to 800 ?m, an injection tube is attached to an injection port for injecting the bone cement of the bag, the bag is inserted into a cavity formed in the vertebra body, and the bone cement is injected and filled into the bag through the tube.

Abstract: The present invention provides a scaffold in which cells can be stably retained and grafted in a uniform distribution state in the culture, preferable proliferation ability and viability can be secured, and particularly in the case of cartilage, fixation treatment such as suture can be carried out in the transplantation into affected parts after the culture, and the mechanical strength is provided sustainable for (weighted) compression at the initial stage of transplantation. The present invention relates to a 3-dimensional porous scaffold for tissue regeneration which comprises a structure composed of vertically long-shaped pores having a pore diameter of not less than 10 ?m to not more than 500 ?m and pore length of not less than 20 ?m to not more than 1 cm being juxtaposedly arranged obtained by a production process comprising rapid freeze-drying as a key technology.

Abstract: A block-shaped scaffold for a tissue engineering with improved shape stability and less volume change in water is produce by the steps of approximate-uniformly mixing the particle-shaped material having 100 to 2000 ?m diameter with a solution, where a biodegradable polymer is dissolved with an organic solvent, freezing, drying it to remove the solvent, pulverizing thus obtained intermediate product, dissolving it with a liquid, where the biodegradable polymer is not dissolved, to remove the particle-shaped material taking thus obtained intermediate product into a mold, and pressing and heating it, the scaffold having ununiform and continuous holes occupying 20 to 80% in a cross-section area in a three-dimensional network structure having a small hole structure with 5 to 50 ?m diameter, elastic coefficient being 0.1 to 2.5 MPa, and volume change being 95 to 105% when dipping it in water for 24 hours.

Abstract: The present invention provides easy operations of moving, rotating, magnifying, and reducing images displayed on a display screen attached to a computer by employing a selecting means. The selecting means having a function to communicate the computer via wireless means, which execute the following procedures to attains the objective of the present invention: detecting a relative position and a posture (a gradient) of itself, displaying the image on the screen in accordance with the moved position and the gradient, selecting the image displayed on the display attached to the computer and outputting (such as printing, etc.) the selected image.

Abstract: A bioabsorbable granular porous bone filling material having a particle diameter 100 to 3000 ?m used for filling a defect part after removing a lesion, or grafting a self bone, and for reinforcing or filling a jawbone when embedding a dental implant, is produced such that the polymer material containing a particle-shaped material and having the small hole structure with the hole diameter of 5 to 50 ?m is made by mixing the particle-shaped material having a diameter of 100 to 2000 ?m with a solution, where the bioabsorbable polymer is dissolved with an organic solvent, the particle-shaped material being not dissolved with this organic solvent but dissolved with a liquid not dissolving the bioabsorbable polymer, freezing it, drying it to remove the organic solvent, pulverizing the produced material, dissolving the particle-shaped material with the liquid to be removed, and sieving it.

Abstract: To provide a surface modified implant made with titanium or a titanium alloy in which a bone bonding can be made easily and certainly as compared with conventional ones and treating method thereof, the surface of the implant made with titanium or the titanium alloy is treated with polyphosphoric acid and basic fibroblast growth factor (bFGF), and the method comprises treating with a polyphosphoric acid solution having a concentration of 0.05 to 70% by weight and with a basic fibroblast growth factor (bFGF) solution having a concentration of 1 to 500 ng/ml, or treating with a mixed solution having the concentration of the polyphosphoric acid of 0.05 to 70% by weight and the concentration of the basic fibroblast growth factor (bFGF) of 1 to 500 ng/ml.

Abstract: A TV receiver having a metal front cabinet is provided with a discharge path between the front cabinet and a ground portion of the TV receiver. The discharge path includes a series circuit in which a discharge tube is connected in series to a parallel circuit of a first resistor and a high-voltage capacitor and a second resistor that is connected in parallel to the series circuit. The discharge path effectively discharges a voltage occurring at the front cabinet via the second resistor while preventing a sudden flow of current and reducing the influence of static electricity. The series circuit in which the discharge tube is connected in series to the parallel circuit of the first resistor and the high-voltage capacitor has a function of causing high-voltage pulses occurring at the ground portion GND to escape to the front cabinet while converting those into pulses having a low voltage level.

Abstract: A remote psychoanalysis system using operation history that allows any person to be subjected to psychological counseling, being not restricted by time and distance.

Abstract: To provide a fixing pin, which can be smoothly stuck into a prepared hole bored in a bone without being broken during fixing a dental guided tissue regeneration membrane, and does not readily drop out but can surely fix the dental guided tissue regeneration membrane after being once stuck, the fixing pin made of a bioabsorbable material for fixing a dental guided tissue regeneration membrane is constructed such that a periphery in an oral cavity inner surface side of a head portion thereof supporting a dental guided tissue regeneration membrane is at least in a smooth curve surface form; and that a thumbtack shaft portion thereof to be stuck into a bone is in a columnar having a conical tip and is provided with two to six ridge portions disposed parallel to the axis of the columnar portion thereof and having a length extending within the bone.

Abstract: This invention relates to an image display apparatus having first image generating means for displaying first image information by a plurality of pixels emitting light, second image generating means for displaying second image information by a plurality of pixels emitting light, the second image information being part of the first image information, visual axis detecting means for detecting an observer's visual axis direction, optical means for combining a first image from the first image generating means and a second image from the second image generating means, moving the second image relative to the first image in conformity with an output signal from the visual axis detecting means and turning it to the observer's pupil, the marginal portion of the second image being made substantially coincident with the boundary between the pixels of the first image when the images are combined, and image display changing means for changing the first image information and the second image information on the ba

Abstract: The present invention provides easy operations of moving, rotating, magnifying, reducing images displayed on a display screen attached to a computer by employing a selecting means. The selecting means having a function to communicate the computer via wireless means, which execute the following procedures to attains the objective of the present invention; detecting a relative position and a posture (a gradient) of itself, displaying the image on the screen in accordance with the moved position and the gradient, selecting the image displayed on the display attached to the computer and outputting (such as printing etc.) the selected image.