Patents by Inventor Tae Heum UM

Tae Heum UM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stabilized external preparation comprising thymosin beta 4 as an active ingredient
    Patent number: 11179443
    Abstract: The present invention relates to a stabilized external preparation comprising thymosin beta 4 (T?4) as an active ingredient. More specifically, the present invention relates to a therapeutically effective external preparation with improved stability and biological activity of T?4. The preparation according to the present invention provides T?4 in a stable state by maintaining the biological activity of T?4 and minimizing the generation of T?4 sulfoxide through oxidization reactions and multimers through aggregation.
    Type: Grant
    Filed: August 4, 2017
    Date of Patent: November 23, 2021
    Assignee: G-TREEBNT CO., LTD.
    Inventors: Jun Won Choi, Kyoungsun Kim, Si Young Lee, Tae Heum Um
  • Method for preparing ophthalmic preparation containing thymosin beta-4
    Patent number: 10744088
    Abstract: The present invention relates to a method for manufacturing an ophthalmic preparation comprising thymosin ?4. According to the inventive method, the manufacture of an ophthalmic preparation comprising thymosin ?4 is carried out in the presence of an inert gas, thus the contact of thymosin ?4 with oxygen is blocked and the oxidation of thymosin ?4 can be prevented and the pharmacological activity of thymosin ?4 maintains for long-term period. Therefore, the ophthalmic preparation prepared by the inventive method can maintain the pharmacological activity of thymosin ?4 in a stable state for a long time.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: August 18, 2020
    Assignee: G-TREEBNT CO., LTD.
    Inventors: Si Young Lee, Sin Wook Kang, Ji Hye Sung, Tae Heum Um
  • STABILIZED EXTERNAL PREPARATION COMPRISING THYMOSIN BETA 4 AS AN ACTIVE INGREDIENT
    Publication number: 20180280479
    Abstract: The present invention relates to a stabilized external preparation comprising thymosin beta 4 (T?4) as an active ingredient. More specifically, the present invention relates to a therapeutically effective external preparation with improved stability and biological activity of T?4. The preparation according to the present invention provides T?4 in a stable state by maintaining the biological activity of T?4 and minimizing the generation of T?4 sulfoxide through oxidization reactions and multimers through aggregation.
    Type: Application
    Filed: August 4, 2017
    Publication date: October 4, 2018
    Applicant: G-TREEBNT CO., LTD.
    Inventors: Jun Won CHOI, Kyoungsun KIM, Si Young LEE, Tae Heum UM
  • METHOD FOR PREPARING OPHTHALMIC PREPARATION CONTAINING THYMOSIN BETA-4
    Publication number: 20180228729
    Abstract: The present invention relates to a method for manufacturing an ophthalmic preparation comprising thymosin ?4. According to the inventive method, the manufacture of an ophthalmic preparation comprising thymosin ?4 is carried out in the presence of an inert gas, thus the contact of thymosin ?4 with oxygen is blocked and the oxidation of thymosin ?4 can be prevented and the pharmacological activity of thymosin ?4 maintains for long-term period. Therefore, the ophthalmic preparation prepared by the inventive method can maintain the pharmacological activity of thymosin ?4 in a stable state for a long time.
    Type: Application
    Filed: December 18, 2015
    Publication date: August 16, 2018
    Applicant: G-TREEBNT CO., LTD.
    Inventors: Si Young LEE, Sin Wook KANG, Ji Hye SUNG, Tae Heum UM