Patents by Inventor Takafumi Hosokawa
Takafumi Hosokawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8927588Abstract: To develop an antibiotic having a novel mechanism of action, the present inventors have searched for a compound that has weak cytotoxicity, the physical property of high solubility in water, the effect of inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and sufficient antibacterial activity. As a result, the present inventors have completed the present invention by finding that a compound of the present invention represented by the general formula (1), a pharmacologically acceptable salt thereof, and a prodrug thereof have desirable properties. The present invention provides a pharmaceutical composition (particularly, a preventive or therapeutic composition for infectious disease) comprising a compound represented by the formula (1), a pharmacologically acceptable salt thereof, or a prodrug thereof as an active ingredient.Type: GrantFiled: September 13, 2013Date of Patent: January 6, 2015Assignee: Daiichi Sankyo Company, LimitedInventors: Tsuyoshi Soneda, Hiroshi Takeshita, Yoshiko Kagoshima, Yuko Yamamoto, Takafumi Hosokawa, Toshiyuki Konosu, Nobuhisa Masuda, Takuya Uchida, Issei Achiwa, Junichi Kuroyanagi, Tetsunori Fujisawa, Aki Yokomizo, Tetsuji Noguchi
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Publication number: 20140141369Abstract: A resin composed of a particular polymer, the particular polymer including a repeating unit containing a structure derived from a dehydroabietic acid, a specific structural unit, and a specific aromatic ring-containing structural unit in the main chain.Type: ApplicationFiled: January 24, 2014Publication date: May 22, 2014Applicant: FUJIFILM CorporationInventors: Takafumi HOSOKAWA, Kiyotaka FUKAGAWA
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Publication number: 20140073622Abstract: To develop an antibiotic having a novel mechanism of action, the present inventors have searched for a compound that has weak cytotoxicity, the physical property of high solubility in water, the effect of inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and sufficient antibacterial activity. As a result, the present inventors have completed the present invention by finding that a compound of the present invention represented by the general formula (1), a pharmacologically acceptable salt thereof, and a prodrug thereof have desirable properties. The present invention provides a pharmaceutical composition (particularly, a preventive or therapeutic composition for infectious disease) comprising a compound represented by the formula (1), a pharmacologically acceptable salt thereof, or a prodrug thereof as an active ingredient.Type: ApplicationFiled: September 13, 2013Publication date: March 13, 2014Applicant: Daiichi Sankyo Company, LimitedInventors: Tsuyoshi Soneda, Hiroshi Takeshita, Yoshiko Kagoshima, Yuko Yamamoto, Takafumi Hosokawa, Toshiyuki Konosu, Nobuhisa Masuda, Takuya Uchida, Issei Achiwa, Junichi Kuroyanagi, Tetsunori Fujisawa, Aki Yokomizo, Tetsuji Noguchi
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Patent number: 8586648Abstract: An aqueous colorant dispersion including a colorant (A), a polymer (B), and an aqueous liquid medium (I), wherein the polymer (B) is a copolymer including a hydrophilic structural unit and a hydrophobic structural unit, the content of the hydrophobic structural unit in the polymer (B) being more than 80% by mass but less than 100% by mass, the hydrophobic structural unit includes a hydrophobic structural unit (a) having an aromatic ring linked via a linking group to an atom included in the main chain of the polymer (B), the content of aromatic rings in the polymer (B) is 10% by mass or more but less than 20% by mass with respect to the mass of the polymer (B), the hydrophilic structural unit includes a hydrophilic structural unit (b) including an ionic group, and the polymer (B) includes a structural unit (c) different from the hydrophobic structural unit (a) and from the hydrophilic structural unit (b), the content of the structural unit (c) in the polymer (B) being more than 15% by mass but less than 90% byType: GrantFiled: February 24, 2009Date of Patent: November 19, 2013Assignee: FUJIFILM CorporationInventors: Takafumi Hosokawa, Misato Sasada, Naoya Shibata
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Patent number: 8536197Abstract: An antibiotic compound having a novel mechanism of action, weak cytotoxicity, high solubility in water, effective in inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and having antibacterial activity.Type: GrantFiled: December 26, 2008Date of Patent: September 17, 2013Assignee: Daiichi Sankyo Company, LimitedInventors: Tsuyoshi Soneda, Hiroshi Takeshita, Yoshiko Kagoshima, Yuko Yamamoto, Takafumi Hosokawa, Toshiyuki Konosu, Nobuhisa Masuda, Takuya Uchida, Issei Achiwa, Junichi Kuroyanagi, Tetsunori Fujisawa, Aki Yokomizo, Tetsuji Noguchi
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Publication number: 20130022907Abstract: Disclosed is a polymer which has a repeating unit containing a skeleton derived from dehydroabietic acid in the main chain, and has a glass transition point of 80° C. or lower.Type: ApplicationFiled: March 30, 2011Publication date: January 24, 2013Applicant: FUJIFILM CORPORATIONInventors: Kiyotaka Fukagawa, Takafumi Hosokawa, Kozo Sato, Toshimitsu Sakuma
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Patent number: 8178597Abstract: An aqueous inkjet recording ink including pigment particles coated with a water-insoluble resin, water, and a water-soluble organic solvent including at least one hydroxy group, wherein the water-insoluble resin has a salt-forming group and a structural unit which is derived from a methacrylate and has an aromatic ring linked via a linking group to an atom in the main chain of the water-insoluble resin, and the water-insoluble resin satisfies the condition that when the water-insoluble resin, an organic solvent, one equivalent of a neutralizing agent with respect to the salt-forming group, and water are mixed with a total content of the water-insoluble resin and the organic solvent being 35% by mass relative to the total mass of the mixture, an emulsion is formed without precipitation of the water-insoluble resin, and after the emulsion is allowed to stand for three hours, a transparent single phase is formed, or two separate phases are formed and at least an aqueous phase of the two phases is transparent.Type: GrantFiled: February 6, 2009Date of Patent: May 15, 2012Assignee: FUJIFILM CorporationInventors: Misato Sasada, Takafumi Hosokawa
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Patent number: 8110616Abstract: An aqueous inkjet recording ink including at least a resin (A), a pigment (B) dispersed with the resin (A), a resin emulsion (C), and an aqueous liquid medium (D), wherein the resin (A) includes hydrophobic structural units (a) and hydrophilic structural units (b), the hydrophobic structural units (a) include a hydrophobic structural unit (a1) in an amount of 40% by mass or more of the resin (A), the hydrophobic structural unit (a1) having an aromatic ring indirectly linked to an atom for forming the main chain of the resin (A), and a hydrophobic structural unit (a2) in an amount of 15% by mass or more of the resin (A), the hydrophobic structural unit (a2) being derived from a C1 to C4 alkyl acrylate or methacrylate, the hydrophilic structural units (b) include a structural unit (b1) derived from an acrylic acid or a methacrylic acid, and the content of the hydrophilic structural units (b) is 15% by mass or less in the resin (A).Type: GrantFiled: February 9, 2009Date of Patent: February 7, 2012Assignee: Fujifilm CorporationInventors: Misato Sasada, Takafumi Hosokawa, Takahiro Kato
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Patent number: 8053040Abstract: A composition comprising at least one liquid crystal compound, and at least one polymer is disclosed. The polymer comprises a constitutional unit represented by a following formula (A) and a constitutional unit derived from a monomer having a fluoroaliphatic group(s): wherein Mp represents a trivalent group constituting fully or partially a polymer main chain; L represents a single bond or a divalent linking group; and X represents a substituted or non-substituted aromatic condensed ring group.Type: GrantFiled: March 13, 2008Date of Patent: November 8, 2011Assignee: FUJIFILM CorporationInventors: Yi Li, Hideyuki Nishikawa, Yuta Takahashi, Masataka Yoshizawa, Takafumi Hosokawa
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Patent number: 8025936Abstract: The present invention aims to provide an optical compensation film that allows superior phase difference between a first optically anisotropic layer and a second optically anisotropic layer and excellent wavelength dispersibility in terms of front and inclined retardation of liquid crystal layers in liquid crystal cells, a polarizing plate containing the optical compensation film, and a liquid-crystal display device that can display superior images with less color change due to the polarizing plate. In order to attain the object, an optical compensation film etc. is provided that comprises at least a first optically anisotropic layer and a second optically anisotropic layer, wherein the first optically anisotropic layer satisfies at least one of the following Equations (i) to (iii): 1?Re1450)(0°)/Re1650)(0°)?1.25:??Equation (i) 1?Re1450)(40°)/Re1650)(40°)?1.25:??Equation (ii) 1?Re1450)(?40°)/Re1650)(?40°)?1.25:??Equation (iii).Type: GrantFiled: November 30, 2006Date of Patent: September 27, 2011Assignee: FUJIFILM CorporationInventors: Ryota Matsubara, Yuta Takahashi, Akira Ikeda, Masaru Yoshikawa, Takafumi Hosokawa, Michio Nagai, Makoto Takahashi
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Patent number: 7998542Abstract: A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula: wherein Mp represents a trivalent linking group; L represents a single bond, or a divalent linking group; X represents a substituted or unsubstituted cyclic linking group; Y represents a single bond, or a divalent linking group; Z represents a substituted or unsubstituted cyclic group; n is 1 to 10.Type: GrantFiled: January 23, 2007Date of Patent: August 16, 2011Assignee: FUJIFILM CorporationInventors: Yi Li, Masaru Yoshikawa, Makoto Takahashi, Takafumi Hosokawa
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Patent number: 7989037Abstract: A composition comprising at least one liquid-crystal compound and a polymer having at least one group of the following formula (A) as the constitutive unit thereof: wherein Mp represents a trivalent linking group; L represents a single bond, or a bivalent linking group; X represents a substituted or unsubstituted functional group having a cyclic structure.Type: GrantFiled: October 4, 2007Date of Patent: August 2, 2011Assignee: FUJIFILM CorporationInventors: Yi Li, Ichiro Nagata, Takafumi Hosokawa, Makoto Takahashi
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Publication number: 20110076466Abstract: The present invention provides a toner composition for electrostatic photography, including a reactive compound A having a reactive group XA, and a reactive compound B having a reactive group XB that is capable of reacting with the reactive group XA and forming a bond, wherein the reactive compound B is capable of forming a three-dimensionally bonded structure by reacting with the reactive compound A, and wherein the toner composition includes the reactive compound A and the reactive compound B in a mutually isolated state. Preferably, the reactive compounds respectively have two or more reaction sites, and any one of the compounds has three or more reaction sites.Type: ApplicationFiled: September 29, 2010Publication date: March 31, 2011Applicant: FUJIFILM CORPORATIONInventors: Hisashi OKAMURA, Kousaku YOSHIMURA, Takafumi HOSOKAWA
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Publication number: 20100311966Abstract: An antibiotic compound having a novel mechanism of action, weak cytotoxicity, high solubility in water, effective in inhibiting both DNA gyrase GyrB and topoisomerase IV ParE subunits, and having antibacterial activity.Type: ApplicationFiled: December 26, 2008Publication date: December 9, 2010Applicant: DAIICHI SANKYO COMPANY, LIMITEDInventors: Tsuyoshi Soneda, Hiroshi Takeshita, Yoshiko Kagoshima, Yuko Yamamoto, Takafumi Hosokawa, Toshiyuki Konosu, Nobuhisa Masuda, Takuya Uchida, Issei Achiwa, Junichi Kuroyanagi, Tetsunori Fujisawa, Aki Yokomizo, Tetsuji Noguchi
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Publication number: 20100216936Abstract: The present invention provides a water-based pigment composition including a pigment; a dispersant; and water, the dispersant including: a repeating unit including an ionic group; at least one of a repeating unit represented by Formula (2) or a repeating unit represented by Formula (3); and a repeating unit represented by Formula (1), a content of the repeating unit represented by Formula (1) being 20% by mass or more but less than 50% by mass with respect to a total amount of repeating units represented by Formulae (1) to (3), which is excellent in stability over time with finely dispersed pigment(s): wherein, in Formulae (1) to (3), R1 represents a hydrogen atom or a methyl group; R2 represents a hydrogen atom or a substituent; L1 represents a single bond or a divalent linkage group; and Ar represents a monovalent aromatic group.Type: ApplicationFiled: January 28, 2010Publication date: August 26, 2010Inventors: Reiko INUSHIMA, Takafumi Hosokawa, Koji Yasuda, Naoya Shibata
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Publication number: 20100078592Abstract: A composition comprising at least one liquid crystal compound, and at least one polymer is disclosed. The polymer comprises a constitutional unit represented by a following formula (A) and a constitutional unit derived from a monomer having a fluoroaliphatic group(s): wherein Mp represents a trivalent group constituting fully or partially a polymer main chain; L represents a single bond or a divalent linking group; and X represents a substituted or non-substituted aromatic condensed ring group.Type: ApplicationFiled: March 13, 2008Publication date: April 1, 2010Applicant: FUJIFILM CorporationInventors: Yi LI, Hideyuki Nishikawa, Yuta Takahashi, Masataka Yoshizawa, Takafumi Hosokawa
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Publication number: 20100076148Abstract: The invention provides an ink composition containing at least: a pigment; one or more water-soluble organic solvent; a neutralizer; and water. At least a part of a surface of the pigment is coated with a copolymer containing at least a repeating unit represented by the following Formula (1) and a repeating unit having an ionic group. The one or more water-soluble organic solvents contains at least a water-soluble organic solvent having a solubility parameter value of 27.5 or less at a content of 90 weight % or more with respect to the total content of the one or more water-soluble organic solvents. In Formula (1), R1 represents a hydrogen atom or a methyl group; L1 represents a substituted or unsubstituted phenylene group; L2 represents a single bond or a divalent linkage group; and Ar represents a monovalent group derived from: a condensed aromatic ring having 8 or more carbon atoms; a hetero ring containing condensed aromatic rings; or two or more linked benzene rings.Type: ApplicationFiled: September 17, 2009Publication date: March 25, 2010Applicant: FUJIFILM CORPORATIONInventors: Naoya SHIBATA, Takafumi HOSOKAWA, Yoshimitsu ARAI
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Publication number: 20090221742Abstract: An aqueous colorant dispersion including a colorant (A), a polymer (B), and an aqueous liquid medium (I), wherein the polymer (B) is a copolymer including a hydrophilic structural unit and a hydrophobic structural unit, the content of the hydrophobic structural unit in the polymer (B) being more than 80% by mass but less than 100% by mass, the hydrophobic structural unit includes a hydrophobic structural unit (a) having an aromatic ring linked via a linking group to an atom included in the main chain of the polymer (B), the content of aromatic rings in the polymer (B) is 10% by mass or more but less than 20% by mass with respect to the mass of the polymer (B), the hydrophilic structural unit includes a hydrophilic structural unit (b) including an ionic group, and the polymer (B) includes a structural unit (c) different from the hydrophobic structural unit (a) and from the hydrophilic structural unit (b), the content of the structural unit (c) in the polymer (B) being more than 15% by mass but less than 90% byType: ApplicationFiled: February 24, 2009Publication date: September 3, 2009Applicant: FUJIFILM CorporationInventors: Takafumi Hosokawa, Misato Sasada, Naoya Shibata
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Publication number: 20090208652Abstract: An ink set for inkjet recording, including: an aqueous ink composition containing a pigment coated with a water-insoluble resin including a structural unit represented by the following formula (I), an organic solvent, a neutralizing agent, and water; and an aqueous liquid composition containing a component which aggregates the pigment in the aqueous ink composition when the aqueous liquid composition is mixed with the aqueous ink composition: wherein R1 represents a hydrogen atom or a methyl group, Ar represents an unsubstituted or substituted aromatic ring, and n represents an average number of repetition of 1 to 6.Type: ApplicationFiled: February 13, 2009Publication date: August 20, 2009Applicant: FUJIFILM CorporationInventors: Misato Sasada, Takafumi Hosokawa
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Publication number: 20090203833Abstract: An aqueous inkjet recording ink including at least a resin (A), a pigment (B) dispersed with the resin (A), a resin emulsion (C), and an aqueous liquid medium (D), wherein the resin (A) includes hydrophobic structural units (a) and hydrophilic structural units (b), the hydrophobic structural units (a) include a hydrophobic structural unit (a1) in an amount of 40% by mass or more of the resin (A), the hydrophobic structural unit (a1) having an aromatic ring indirectly linked to an atom for forming the main chain of the resin (A), and a hydrophobic structural unit (a2) in an amount of 15% by mass or more of the resin (A), the hydrophobic structural unit (a2) being derived from a C1 to C4 alkyl acrylate or methacrylate, the hydrophilic structural units (b) include a structural unit (b1) derived from an acrylic acid or a methacrylic acid, and the content of the hydrophilic structural units (b) is 15% by mass or less in the resin (A).Type: ApplicationFiled: February 9, 2009Publication date: August 13, 2009Applicant: FUJIFILM CorporationInventors: Misato SASADA, Takafumi Hosokawa, Takahiro Kato