Abstract: [Problem] A compound useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer is provided. [Solution] The present inventors have studied about a compound that is useful as an active ingredient of a pharmaceutical composition for treating pancreatic cancer and have found that a 4-aminoquinazoline compound has an excellent G12D mutant KRAS inhibition activity and can be used as a therapeutic agent for pancreatic cancer, thus completing the present invention. The 4-aminoquinazoline compound of the present invention or a salt thereof can be used as a therapeutic agent for pancreatic cancer.

Abstract: An optical sensor includes a light-emitting element configured to project light that changes with time; a light-receiving element including a pn junction and configured to directly or indirectly receive the light projected by the light-emitting element; a measuring section configured to measure an electric current generated based on an amount of the light received by the light-receiving element; and a bias application section configured to apply a bias to the light-receiving element, wherein the bias application section, before measuring the electric current generated based on the amount of the light received, applies the bias to the light-receiving element to cause either a forward current that flows when the light-receiving element is turned ON or a breakdown current that flows when the pn junction breaks down to flow through the pn junction.

Abstract: A measurement device according to an aspect includes a belt portion configured to be wrapped around a target measurement site of a user, an electrocardiogram measurement unit provided in the belt portion and configured to measure an electrocardiogram reading of the user, a blood pressure measurement unit provided in the belt portion and configured to measure blood pressure of the user, a measurement end detection unit configured to detect an end of the electrocardiogram measurement by the electrocardiogram measurement unit, and a blood pressure measurement control unit configured to start blood pressure measurement by the blood pressure measurement unit in response to the measurement end detection unit that has detected the end of the electrocardiogram measurement.

Abstract: A measurement device includes a pressure acquisition unit configured to acquire pressure information representing pressure in a pressing cuff, a cuff pressure control unit configured to control, based on the pressure information, the pressure in the pressing cuff during each of a pressurizing step of pressurizing the pressing cuff, a pressurized state maintaining step of maintaining the pressing cuff in a pressurized state after end of the pressurizing step, and a depressurizing step of depressurizing the pressing cuff after end of the pressurized state maintaining step, a blood pressure calculation unit configured to calculate a blood pressure of a user based on the pressure information, and an electrocardiographic measurement unit configured to measure an electrocardiogram of the user during the pressurized state maintaining step.

Abstract: When creating a medical questionnaire of a patient, a medical questionnaire creation assist terminal acquires past clinical data of the patient from an EMR server or an EHR server on the basis of medical questionnaire template data, and also acquires PHR data from a mobile information terminal of the patient to create medical questionnaire basic data. Then, the medical questionnaire creation assist terminal creates medical questionnaire completed data by adding medical interview statement information manually input by the patient or medical staff to incomplete items in the medical questionnaire basic data, and notifies a physician terminal of the medical questionnaire completed data.

Abstract: A behavior modification assistance device includes an acquisition unit acquiring biological data and behavioral data regarding a user, a biological indicator generation unit generating a biological indicator of the user based on the biological data, a behavioral indicator generation unit generating, based on the behavioral data, a behavioral indicator representing an achievement of a behavior by the user affecting the biological indicator, a calculation unit calculating, based on the biological indicator and the behavioral indicator, a requirement level representing, at two or more levels, a need for the user to modify behavior, a determination unit determining, based on the requirement level, an instructor who provides guidance and encourages the user to modify behavior, from among a plurality of candidates including at least a person other than the user, and a guidance request generation unit generating guidance request data requesting the instructor to provide the guidance.

Abstract: Health-related information is provided suitable for a subject. An information processing device includes an acquisition unit that acquires first information indicating a subject's interest in health, an estimation unit that estimates a subject's degree of interest in health based on the first information, a selection unit that selects second information regarding health to be provided to the subject based on the degree of interest, and an output unit that outputs the second information.

Abstract: An LSI which makes scan testing possible without compromising security is provided. Flip-flops that constitute a scan chain are reset when scan testing is initiated or terminated by the edges of a mode signal for switching between normal operations and scan testing. In addition, during scan testing, internal memory means is made inaccessible. Further, a dummy flip-flop that operates only during scan testing is connected to the scan chain, and shifting out by the scan chain during normal operations is made impossible.

Abstract: An LSI which makes scan testing possible without compromising security is provided. Flip-flops that constitute a scan chain are reset when scan testing is initiated or terminated by the edges of a mode signal for switching between normal operations and scan testing. In addition, during scan testing, internal memory means is made inaccessible. Further, a dummy flip-flop that operates only during scan testing is connected to the scan chain, and shifting out by the scan chain during normal operations is made impossible.