Patents by Inventor Takaishi Komatsu

Takaishi Komatsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing the permeability of the blood brain barrier
    Patent number: 7012061
    Abstract: The present invention relates to a method for regulating the permeability of the blood brain barrier by administering a NOS-3 inhibitor to reduce the increased permeability of the blood brain barrier caused by a pathological condition or by administering a NOS-3 activator or nitric oxide donor to increase the permeability of the blood brain barrier. By increasing the permeability of the blood barrier, a therapeutic or diagnostic compound can be delivered across this barrier into the central nervous system.
    Type: Grant
    Filed: October 19, 1999
    Date of Patent: March 14, 2006
    Assignee: New York University
    Inventors: Carol Shoshkes Reiss, Takaishi Komatsu