Patents by Inventor Takao Omae

Takao Omae has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9045426
    Abstract: The present inventions provide a method for commercially producing a 1,2 -dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2 -dihydropyridin-2-one and production processes therefore.
    Type: Grant
    Filed: January 27, 2014
    Date of Patent: June 2, 2015
    Assignee: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Itaru Arimoto, Satoshi Nagato, Yukiko Sugaya, Yoshio Urawa, Koichi Ito, Hiroyuki Naka, Takao Omae, Akio Kayano, Katsutoshi Nishiura
  • Patent number: 8772497
    Abstract: The present inventions provide a method for commercially producing a 1,2-dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one and production processes therefore.
    Type: Grant
    Filed: August 27, 2010
    Date of Patent: July 8, 2014
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Itaru Arimoto, Satoshi Nagato, Yukiko Sugaya, Yoshio Urawa, Koichi Ito, Hiroyuki Naka, Takao Omae, Akio Kayano, Katsutoshi Nishiura
  • Publication number: 20140142315
    Abstract: The present inventions provide a method for commercially producing a 1,2-dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one and production processes therefore.
    Type: Application
    Filed: January 27, 2014
    Publication date: May 22, 2014
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Itaru ARIMOTO, Satoshi NAGATO, Yukiko SUGAYA, Yoshio URAWA, Koichi ITO, Hiroyuki NAKA, Takao OMAE, Akio KAYANO, Katsutoshi NISHIURA
  • Patent number: 8436009
    Abstract: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.
    Type: Grant
    Filed: May 18, 2011
    Date of Patent: May 7, 2013
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Masanobu Shinoda, Shinsuke Hirota, Kazunobu Kira, Hiroshi Azuma, Atsushi Takemura, So Yasui, Kazutomi Kusano, Masaki Mikamoto, Takao Omae
  • Publication number: 20130053563
    Abstract: By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.
    Type: Application
    Filed: May 18, 2011
    Publication date: February 28, 2013
    Applicant: EISAI R&D MANAGEMENT CO., LTD.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Masanobu Shinoda, Shinsuke Hirota, Kazunobu Kira, Hiroshi Azuma, Atsushi Takemura, So Yasui, Kazutomi Kusano, Masaki Mikamoto, Takao Omae
  • Patent number: 8163787
    Abstract: A compound represented by the following general formula (1) or salts thereof or hydrates of the foregoing: wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.; and Z1 and Z2 each independently represent hydrogen.
    Type: Grant
    Filed: January 13, 2011
    Date of Patent: April 24, 2012
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Kazunobu Kira, Shinsuke Hirota, Hiroshi Azuma, Tadashi Nagakura, Tatsuo Horizoe, Kimiyo Tabata, Kazutomi Kusano, Takao Omae, Atsushi Inoue
  • Publication number: 20110112109
    Abstract: A compound represented by the following general formula (1) or salts thereof or hydrates of the foregoing: wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.; and Z1 and Z2 each independently represent hydrogen.
    Type: Application
    Filed: January 13, 2011
    Publication date: May 12, 2011
    Inventors: Richard CLARK, Fumiyoshi Matsuura, Kazunobu Kira, Shinsuke Hirota, Hiroshi Azuma, Tadashi Nagakura, Tatsuo Horizoe, Kimiyo Tabata, Kazutomi Kusano, Takao Omae, Atsushi Inoue
  • Patent number: 7928228
    Abstract: A Compound represented by the following general formula (1): wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.; and Z1 and Z2 each independently represent hydrogen or salts thereof or hydrates of the foregoing.
    Type: Grant
    Filed: March 29, 2010
    Date of Patent: April 19, 2011
    Assignees: Eisai Co., Ltd., Eisai R&D Management Co., Ltd.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Kazunobu Kira, Shinsuke Hirota, Hiroshi Azuma, Tadashi Nagakura, Tatsuo Horizoe, Kimiyo Tabata, Kazutomi Kusano, Takao Omae, Atsushi Inoue
  • Publication number: 20100324297
    Abstract: The present inventions provide a method for commercially producing a 1,2-dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one and production processes therefore.
    Type: Application
    Filed: August 27, 2010
    Publication date: December 23, 2010
    Inventors: Itaru ARIMOTO, Satoshi Nagato, Yukiko Sugaya, Yoshio Urawa, Koichi Ito, Hiroyuki Naka, Takao Omae, Akio Yayano, Katsutoshi Nishiura
  • Patent number: 7816522
    Abstract: A Compound represented by the following general formula (1), salts thereof or hydrates of the foregoing is a novel compound useful for treatment and/or prevention of diseases associated with thrombus formation, and which is safer with suitable physicochemical stability. [wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: October 19, 2010
    Assignee: Eisai Co., Ltd.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Kazunobu Kira, Shinsuke Hirota, Hiroshi Azuma, Tadashi Nagakura, Tatsuo Horizoe, Kimiyo Tabata, Kazutomi Kusano, Takao Omae, Atsushi Inoue
  • Patent number: 7803818
    Abstract: An amorphous form of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridine-2-one.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: September 28, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Takao Omae, Yukiko Sugaya
  • Publication number: 20100190783
    Abstract: A Compound represented by the following general formula (1): wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.; and Z1 and Z2 each independently represent hydrogen or salts thereof or hydrates of the foregoing.
    Type: Application
    Filed: March 29, 2010
    Publication date: July 29, 2010
    Inventors: Richard CLARK, Fumiyoshi MATSUURA, Kazunobu KIRA, Shinsuke HIROTA, Hiroshi AZUMA, Tadashi NAGAKURA, Tatsuo HORIZOE, Kimiyo TABATA, Kazutomi KUSANO, Takao OMAE, Atsushi INOUE
  • Patent number: 7754894
    Abstract: A crystalline form of N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzenesulfonamide having a diffraction peak at a diffraction angle (2?±0.2°) of 19.1° in a powder X-ray diffraction.
    Type: Grant
    Filed: September 1, 2004
    Date of Patent: July 13, 2010
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Keiko Takahashi, Kenji Hayashi, Taichi Abe, Takao Omae, Takashi Kato
  • Publication number: 20090247768
    Abstract: A crystalline form of N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzenesulfonamide having a diffraction peak at a diffraction angle (2?±0.2°) of 19.1° in a powder X-ray diffraction.
    Type: Application
    Filed: June 9, 2009
    Publication date: October 1, 2009
    Inventors: Keiko Takahashi, Kenji Hayashi, Taichi Abe, Takao Omae, Takashi Kato
  • Publication number: 20080312284
    Abstract: An amorphous form of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridine-2-one.
    Type: Application
    Filed: December 20, 2006
    Publication date: December 18, 2008
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Takao Omae, Yukiko Sugaya
  • Patent number: 7420295
    Abstract: The present invention provides a power unit for conveyance, having a main power source and a standby power source. The power unit has a thermal battery provided as the standby power source. The conveyance is provided with an electronic control system and the power unit for conveyance of the present invention, and electric power for operating the electronic control system is supplied to the electronic control system from the power unit for conveyances. By employing such a thermal battery as the standby power source, the standby power source does not require to be charged, thereby ensuring a long-term reliability of the standby power source.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: September 2, 2008
    Assignee: GS Yuasa Corporation
    Inventors: Takao Omae, Ken Sawai
  • Publication number: 20080015199
    Abstract: A Compound represented by the following general formula (1), salts thereof or hydrates of the foregoing is a novel compound useful for treatment and/or prevention of diseases associated with thrombus formation, and which is safer with suitable physicochemical stability. [wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.
    Type: Application
    Filed: March 22, 2007
    Publication date: January 17, 2008
    Applicant: Eisai R&D Management Co., Ltd.
    Inventors: Richard Clark, Fumiyoshi Matsuura, Kazunobu Kira, Shinsuke Hirota, Hiroshi Azuma, Tadashi Nagakura, Tatsuo Horizoe, Kimiyo Tabata, Kazutomi Kusano, Takao Omae, Atsushi Inoue
  • Publication number: 20070142640
    Abstract: The present inventions provide a method for commercially producing a 1,2-dihydropyridine-2-one compound represented by the following formula (III-a) wherein the ring A represents an optionally substituted 2-pyridyl group, the ring B represents an optionally substituted phenyl group, and the ring C represents an optionally substituted phenyl group. Further, the invention provides crystals of 3-(2-cyanophenyl)-5-(2-pyridyl)-1-phenyl-1,2-dihydropyridin-2-one and production processes therefor.
    Type: Application
    Filed: January 4, 2007
    Publication date: June 21, 2007
    Inventors: Itaru Arimoto, Satoshi Nagato, Yukiko Sugaya, Yoshio Urawa, Koichi Ito, Hiroyuki Naka, Takao Omae, Akio Kayano, Katsutoshi Nishiura
  • Publication number: 20070082941
    Abstract: A crystalline form of N-(3-cyano-4-methyl-1H-indol-7-yl)-3-cyanobenzenesulfonamide having a diffraction peak at a diffraction angle (2?±0.2°) of 19.1° in a powder X-ray diffraction.
    Type: Application
    Filed: September 1, 2004
    Publication date: April 12, 2007
    Applicant: Eisai Co., Ltd.
    Inventors: Keiko Takahashi, Kenji Hayashi, Taichi Abe, Takao Omae, Takashi Kato
  • Publication number: 20050253458
    Abstract: This invention aims to improve the reliability of an electronic control system which drives an actuator on conveyance operation based on an electrical signal to make adjustments such as acceleration/deceleration and movement direction of a conveyance, by achieving a power unit for conveyances having a power source with no need of charge and with little performance deterioration, thereby allowing for practical application of high-performance conveyances. The present invention relates to a power unit for conveyance comprising a main power source and a stand-by power source, which is characterized in that a thermal battery is provided as the stand-by power source, and a conveyance which is provided with an electronic control system and the power unit for conveyance of the present invention, is constituted so that electric power for operating the electronic control system is supplied to the electronic control system from the power unit for conveyances.
    Type: Application
    Filed: July 31, 2003
    Publication date: November 17, 2005
    Applicant: JAPAN STORAGE BATTERY CO., LTD.
    Inventors: Takao Omae, Ken Sawai