Patents by Inventor Takashi Endoh

Takashi Endoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antitussive agents
    Patent number: 5739145
    Abstract: There are provided novel antitussive agents different from existing antitussive agents or those under development. Antitussive agents containing morphinan derivatives represented by compound 6: ##STR1## or pharmacologically acceptable acid-addition salts thereof and those derivatives or their salts as effective components.The antitussive agents according to the present invention have strong antitussive effects as highly selective .kappa.-opioid agonists, and may thus be applied as useful antitussive agents in the prophylaxis and treatment of coughing in a patient in need thereof.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: April 14, 1998
    Assignee: Toray Industries, Inc.
    Inventors: Hiroshi Nagase, Koji Kawai, Takashi Endoh, Shinya Ueno, Yuji Negishi
  • Drainage pump
    Patent number: 5605439
    Abstract: A drainage pump 1 comprises a pump housing 40 defining a suction inlet 42, a pumping chamber 44 and a delivery outlet 46, and a cover 32. An impeller 50 accommodated in the pump housing is driven by a motor 10. The impeller 50 comprises a shaft 52 coupled to an output shaft of the motor 10, large-radius vanes 60 in form of flat plates radially extending from the shaft 52, and small-radius vanes 54 continuous from the large-radius vanes 60. Outer circumferential edges of the large-radius vanes 60 are connected by a cylindrical wall member 64, and outer circumferential parts of lower edges of the large-radius vanes 60 are connected by an annular member 62. The cylindrical wall member 64 has a rounded portion 70 at its upper end, and the small-radius vanes 54 also have rounded portions 57 at their lower ends.
    Type: Grant
    Filed: May 22, 1996
    Date of Patent: February 25, 1997
    Assignee: Fujikoki Corporation
    Inventors: Takashi Endoh, Tatsushi Ninomiya, Masayuki Imai
  • Immunosuppressive agent and process of producing the same
    Patent number: 5332818
    Abstract: An immunosuppressive agent which has low toxicity and which exhibits excellent effectiveness even if it is orally administered is presented. The immunosuppressive agent of the present invention is characterized in that it contains .delta.-opioid antagonist having high selectivity to .delta.-opioid receptor. The present invention also provides a process of producing a naltrindole derivative characterized by reacting naltrexone or a salt thereof with a phenylhydrazine derivative in a solvent in the presence of methanesulfonic acid.
    Type: Grant
    Filed: March 22, 1993
    Date of Patent: July 26, 1994
    Assignee: Toray Industries, Inc.
    Inventors: Hiroshi Nagase, Koji Kawai, Shu Matsumoto, Takashi Endoh, Yoshiaki Katsura, Kohei Arakawa
  • 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI.sub.2 derivatives
    Patent number: 5086071
    Abstract: Pharmaceutically useful compounds are 2,5,6,7-tetranor-4,8-inter-m-phenylene PGI.sub.2 derivatives which are excellently stable and potent in vivo.
    Type: Grant
    Filed: March 13, 1990
    Date of Patent: February 4, 1992
    Assignee: Toray Industries, Inc.
    Inventors: Kiyotaka Ohno, Atsushi Ohtake, Takashi Endoh, Shigeki Itou, Kazuhiro Hoshi