Abstract: A beverage supply apparatus 100 includes milk tank 3, milk flow path L3, pump 7 for delivering a beverage, air flow path L6, pump 9 for supplying air configured to be capable of changing the discharge flow rate, release path L7 for discharging air flowing through air flow path L6 to the outside, on-off valve V7, first throttle part 16, and second throttle part 17. One end of release path L7 is connected to release point Z8 in air flow path L6, and the other end is open to the outside. On-off valve V7 is disposed in a flow path extending between release point Z8 and pump 9 in air flow path L6, and opens and closes this flow path. Throttle part 16 is disposed in a flow path extending downstream of release point Z8 in air flow path L6, and throttle part 17 is disposed in release path L7.

Abstract: Beverage supply apparatus (100) has milk tank (3), milk flow path (L3) connecting the milk tank to beverage delivery port (10), first pump (7), air flow path (L6) to supply air via its connection portion (Z1), and third pump (9). The apparatus drives the third pump to supply air to the milk flow path, and drives the first pump to thereby deliver and supply a mixed beverage of milk and air from the beverage delivery port. The apparatus includes path (L7) for releasing a portion of the air flowing through the air flow path, one end portion of which is connected to release point (Z8) which is a predetermined portion of the air flow path between a beverage flow path side end portion (location of a connection portion (Z6)) and the third pump. The other end portion thereof is open to the outside.

Abstract: Beverage supply apparatus (100) has milk tank (3), milk flow path (L3) connecting the milk tank to beverage delivery port (10), first pump (7), air flow path (L6) to supply air via its connection portion (Z1), and third pump (9). The apparatus drives the third pump to supply air to the milk flow path, and drives the first pump to thereby deliver and supply a mixed beverage of milk and air from the beverage delivery port. The apparatus includes path (L7) for releasing a portion of the air flowing through the air flow path., one end portion of which is connected to release point (Z8) which is a predetermined portion of the air flow path between a beverage flow path side end portion (location of a connection portion (Z6)) and the third pump. The other end portion thereof is open to the outside.

Abstract: A beverage supply apparatus 100 includes milk tank 3, milk flow path L3, pump 7 for delivering a beverage, air flow path L6, pump 9 for supplying air configured to be capable of changing the discharge flow rate, release path L7 for discharging air flowing through air flow path L6 to the outside, on-off valve V7, first throttle part 16, and second throttle part 17. One end of release path L7 is connected to release point Z8 in air flow path L6, and the other end is open to the outside. On-off valve V7 is disposed in a flow path extending between release point Z8 and pump 9 in air flow path L6, and opens and closes this flow path. Throttle part 16 is disposed in a flow path extending downstream of release point Z8 in air flow path L6, and throttle part 17 is disposed in release path L7.

Abstract: This invention provides a therapeutic agent for inhibiting neovascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, and a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Based on the finding that vascularization is suppressed in CXCR4 knockout mice, it becomes possible to prepare a therapeutic agent for suppressing vascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, each of which comprises as the effective ingredient, a substance that inhibits the action of CXCR4, as well as to prepare a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Methods for treatment are made possible that use these therapeutic agents.

Abstract: This invention provides a therapeutic agent for inhibiting neovascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, and a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Based on the finding that vascularization is suppressed in CXCR4 knockout mice, it becomes possible to prepare a therapeutic agent for suppressing vascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, each of which comprises as the effective ingredient, a substance that inhibits the action of CXCR4, as well as to prepare a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4. Methods for treatment are made possible that use these therapeutic agents.

Abstract: The invention provides a beverage extractor permitting extraction of a beverage of high quality irrespective of its type. The extractor is provided with a first extraction channel for letting the beverage extracted in a cylinder flow into the extraction pipe via beverage outlet holes of a second piston having a prescribed first bore and a second extraction channel via a communication hole having a prescribed second bore, which is smaller in bore than the outlet holes, for letting the beverage extracted in the cylinder flow into the extraction pipe, and the first and second extraction channels are switched over between each other by the movement of the second piston. This makes it possible to select an extraction channel suitable for the type of beverage, whether regular coffee or espresso coffee, and accordingly to extract a beverage of high quality irrespective of the type of beverage.

Abstract: The present invention pertains to a DNA encoding a polypeptide including an entire sequence of the amino acid sequence as shown by SEQ ID NO: 2 or a partial sequence thereof, or a polypeptide including the polypeptide described above, wherein any of the polypeptides has an activity of a receptor capable of binding to a murine PBSF/SDF-1; a polypeptide encoded by the DNA described above, wherein the polypeptide has an activity of a receptor capable of binding to a murine PBSF/SDF-1; cells expressing the polypeptide described above and a human CD4 protein; and a method of screening an AIDS onset inhibitor or an HIV-1 infection inhibitor, characterized by the use of the cells described above. According to the present invention, there can be provided a novel murine CXC chemokine receptor gene, a method of screening an HIV-1 infection inhibitor, and the like, each of which is useful in studies of a therapeutic agent for AIDS and the functional mechanism of HIV-1 infection.

Abstract: The invention provides a beverage extractor permitting extraction of a beverage of high quality irrespective of its type. The extractor is provided with a first extraction channel for letting the beverage extracted in a cylinder flow into the extraction pipe via beverage outlet holes of a second piston having a prescribed first bore and a second extraction channel via a communication hole having a prescribed second bore, which is smaller in bore than the outlet holes, for letting the beverage extracted in the cylinder flow into the extraction pipe, and the first and second extraction channels are switched over between each other by the movement of the second piston. This makes it possible to select an extraction channel suitable for the type of beverage, whether regular coffee or espresso coffee, and accordingly to extract a beverage of high quality irrespective of the type of beverage.

Abstract: The present invention pertains to a DNA encoding a polypeptide including an entire sequence of the amino acid sequence as shown by SEQ ID NO: 2 or a partial sequence thereof, or a polypeptide including the polypeptide described above, wherein any of the polypeptides has an activity of a receptor capable of binding to a murine PBSF/SDF-1; a polypeptide encoded by the DNA described above, wherein the polypeptide has an activity of a receptor capable of binding to a murine PBSF/SDF-1; cells expressing the polypeptide described above and a human CD4 protein; and a method of screening an AIDS onset inhibitor or an HIV-1 infection inhibitor, characterized by the use of the cells described above. According to the present invention, there can be provided a novel murine CXC chemokine receptor gene, a method of screening an HIV-1 infection inhibitor, and the like, each of which is useful in studies of a therapeutic agent for AIDS and the functional mechanism of HIV-1 infection.

Abstract: The present invention pertains to a DNA encoding a polypeptide comprising an entire sequence of the amino acid sequence as shown by SEQ ID NO:2 of Sequence Listing or a partial sequence thereof, or a polypeptide comprising the polypeptide described above, wherein any of the polypeptides has an activity of a receptor capable of binding to a murine PBSF/SDF-1; a polypeptide encoded by the DNA described above, wherein the polypeptide has an activity of a receptor capable of binding to a murine PBSF/SDF-1; cells expressing the polypeptide described above and a human CD4 protein; and a method of screening an AIDS onset inhibitor or an HIV-1 infection inhibitor, characterized by the use of the cells described above. According to the present invention, there can be provided a novel murine CXC chemokine receptor gene, a method of screening an HIV-1 infection inhibitor, and the like, each of which is useful in studies of a therapeutic agent for AIDS and the functional mechanism of HIV-1 infection.

Abstract: This invention provides a therapeutic agent for inhibiting neovascularization, a therapeutic agent for a solid cancer, a therapeutic agent for a disease pathologically caused by neovascularization, and a therapeutic agent for repairing a tissue comprising as the effective ingredient, a substance that potentiates the action of CXCR4.

Abstract: A structure for supporting a connecting member having a base material for electrically and temporarily connecting a first substrate having a terminal and a second substrate having a connection pad with each other. A supporting point of a point for contacting between the second substrate and the connecting member and a supporting point of the first substrate are separated thermally.

Abstract: In an automatic vending machine for vending a beverage poured into a cup, a washing position is determined for a wash of a cup holder (3) which is for holding the cup. A driving unit (57,63) can move the cup holder under control of a control unit which is for controlling operation of the automatic vending machine. Before the cup holder is washed, the driving unit makes the cup holder be placed at the washing position that may be determined by a washing nozzle (80) for discharging washing water.

Abstract: An adhesive composition comprising an alpha-cyanoacrylate monomer and a phosphazene compound incorporated therein and improved in storage stability without deterioration of the adhesion rate and the adhesive strength.

Abstract: A self-straightening tape measure which is commonly called a convex rule, has hitherto been prepared exclusively of steel, however, the tape measure of steel is not only liable to be rusted but also is dangerous owing to good conductor of electricity when used in the vicinity of electric wires. In order to eliminate the above disadvantages, the present invention provides a self-straightening tape measure of resin, which is prepared by impregnating a tape material of crossing fibers with a large amount of thermosetting resin, bending the tape material in the width direction to form an arc in cross section, so that the arc may occupy from one-third to three-fourths of the whole circumference of the circle described by extending the arc, and heating the tape material to harden the resin and to have the said arcuate form.

Abstract: Intake arrangement of an internal combustion engine comprises an air intake passageway and an air-fuel mixture intake passageway with its port arranged radially inwardly of the air intake passageway. Port opening period of the air-fuel mixture intake port is full overlapped with and shorter than port opening period of air intake port of the air intake passageway.