Patents by Inventor Takayuki Kondo
Takayuki Kondo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210072242Abstract: The present invention derives from the unexpected finding that necroptosis is a novel biomarker and target for therapy in patients with liver failure such as acute liver failure (ALF) and acute-on-chronic liver failure (ACLF). RIPK1, MLKL or RIPK3 can be detected and quantified in serum or plasma, and used as a biomarker for outcome in ACLF and other diseases involving aberrant necroptosis. By antagonising RIPK1, MLKL or RIPK3 many of the unwanted consequences or symptoms of acute-on-chronic liver failure (ACLF) may be reduced. The present invention utilises these findings to identify and provide antagonists of RIPK1, MLKL and RIPK3 that may be used in the treatment or prevention of ACLF. The present invention utilises these findings to identify and provide antagonists of RIPK1, MLKL or RIPK3 that may be used in the treatment or prevention of aberrant necroptosis in the kidney, brain, liver or other organ of the body.Type: ApplicationFiled: September 21, 2020Publication date: March 11, 2021Inventors: Rajiv JALAN, Fausto ANDREOLA, Stewart MACDONALD, Takayuki KONDO
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Publication number: 20210071628Abstract: There is provided a damper device that can be held in a housing space with simple work. A damper device, which is disposed and used in a housing space formed in a device unit, includes: a damper body that is filled with gas and includes a diaphragm provided with a deformable-action portion formed at a central portion thereof; and an annular clip that holds an outer peripheral edge portion of the damper body and causes a biasing force to act on an inner wall of a cover member, which forms the housing space, in a radial direction.Type: ApplicationFiled: May 22, 2019Publication date: March 11, 2021Inventors: Toshiaki IWA, Yoshihiro OGAWA, Yusuke SATO, Koji SATO, Takayuki KONDO
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Publication number: 20210005896Abstract: A positive electrode of a lithium secondary battery includes a sheet-like positive electrode current collector having conductivity, and a positive electrode active material plate that is a plate-like ceramic sintered compact joined to the positive electrode current collector via a conductive joint layer. The positive electrode active material plate includes at least one active material plate element. This at least one active material plate element is joined to the positive electrode current collector. A main surface of the active material plate element that opposes the positive electrode current collector includes a joint region in which the conductive joint layer exists between the positive electrode current collector and the active material plate element and a non-joint region in which the conductive joint layer does not exist between the positive electrode current collector and the active material plate element. The non joint region is arranged around the joint region.Type: ApplicationFiled: September 14, 2020Publication date: January 7, 2021Applicant: NGK INSULATORS, LTD.Inventors: Masahiko HIBINO, Takayuki KONDO, Tetsushige YOSHIDA
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Patent number: 10845218Abstract: An encoder includes a base portion, a rotation portion that is provided to be rotatable about a rotation axis with respect to the base portion, a mark that is disposed around the rotation axis on the rotation portion, an imaging element that is disposed in the base portion and images the marks, a storage portion that stores a reference image, and a determination portion that performs template matching on the mark imaged by the imaging element by using the reference image, so as to determine a rotation state of the rotation portion with respect to the base portion.Type: GrantFiled: January 17, 2018Date of Patent: November 24, 2020Inventor: Takayuki Kondo
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Patent number: 10793819Abstract: A liquid injection method for injecting a liquid into a culture vessel includes tilting the culture vessel around a horizontal axis at a tilt angle (X°) of greater than 0° and 50° or less, wherein adherent cells are adhered to the culture vessel; and injecting the liquid into the culture vessel at a predetermined linear velocity (Y mm/s) via a wall surface of the culture vessel tilted at the tilt angle (X°), wherein the tilt angle (X) and the linear velocity (Y) satisfy the following (formula 1): Y?5.075X+123 (formula 1).Type: GrantFiled: December 21, 2017Date of Patent: October 6, 2020Assignees: KANEKA CORPORATION, KYOTO UNIVERSITYInventors: Tomohisa Kato, Kazuya Hamada, Haruhisa Inoue, Takayuki Kondo
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Patent number: 10788814Abstract: An encoder includes a base portion, a scale portion that is provided to be relatively rotatable with respect to the base portion, and has a plurality of marks, an imaging element that is disposed in the base portion, and images the marks, and an estimation portion that performs template matching on a captured image in the imaging element by using a reference image, in which the plurality of marks include a first mark and a second mark, and the estimation portion counts the number of pixels of the imaging element corresponding to a rotation angle of the scale portion with respect to the base portion until a position of the second mark is detected from detection of a position of the first mark, and performs calibration on the basis of the counted number of pixels and the rotation angle.Type: GrantFiled: October 23, 2018Date of Patent: September 29, 2020Assignee: Seiko Epson CorporationInventors: Daiki Tokushima, Takayuki Kondo
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Patent number: 10775204Abstract: Template matching with an image captured by the first imaging element is performed to obtain a first movement amount in a circumferential direction of the first mark, template matching with an image captured by the second imaging element is performed to obtain a second movement amount in a circumferential direction of the second mark, and a rotation angle is calculated and output by using the first movement amount and the second movement amount.Type: GrantFiled: February 14, 2019Date of Patent: September 15, 2020Assignee: Seiko Epson CorporationInventor: Takayuki Kondo
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Patent number: 10759055Abstract: An encoder includes a base portion, a scale portion that is provided to be relatively movable or rotatable with respect to the base portion, and has three or more marks which are different from each other, an imaging element that is disposed in the base portion, and images the marks, and an estimation portion that selects at least one reference image from among three or more reference images, performs template matching on a captured image in the imaging element by using the reference image, so as to detect positions of the marks, and estimates a movement state or a rotation state of the scale portion with respect to the base portion, in which the estimation portion predicts a reference image to be used for post-template matching on the basis of a result of pre-template matching, and performs the post-template matching by using the predicted reference image.Type: GrantFiled: September 27, 2018Date of Patent: September 1, 2020Assignee: Seiko Epson CorporationInventors: Takayuki Kondo, Daiki Tokushima
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Patent number: 10753328Abstract: A fuel supply device has a cover member which is attached to an opening of a fuel tank, a pump unit provided with a pump, and a connecting portion for connecting the cover member and the pump unit. The fuel supply device has a connecting shaft which is formed on either one of the connecting portion or the pump unit, and a connecting hole which is formed on the other. The fuel supply device has a guide mechanism which can guide the pump unit. The guide mechanism includes a first guide portion formed at the connecting portion and a second guide portion formed at the pump unit. One of the first guide portion or the second guide portion includes a protruding portion which protrudes in a position spaced apart from the connecting shaft. The other guide portion is formed to restrict a movable range of the protruding portion.Type: GrantFiled: August 10, 2015Date of Patent: August 25, 2020Assignee: ASIAN KOGYO KABUSHIKI KAISHAInventors: Yuichi Murakoshi, Koji Yoshida, Tatsuki Fukui, Shinya Higashi, Takuya Kono, Takayuki Kondo, Akihiro Yano
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Publication number: 20200246510Abstract: A resin composition for a medical device to be subjected to gas low-temperature sterilization includes a resin and an ion exchanger.Type: ApplicationFiled: April 23, 2020Publication date: August 6, 2020Applicant: OLYMPUS CORPORATIONInventors: Koji KOBAYASHI, Takayuki KONDO, Rieko NIINO, Masaya IWAMOTO
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Publication number: 20200018395Abstract: A piston ring which is resinous includes an annular main body portion having an inner peripheral surface and an outer peripheral surface facing each other and a pair of side surfaces interconnecting the inner peripheral surface and the outer peripheral surface and a joint portion 3 formed in the main body portion. The joint portion has a step shape when viewed from at least one of the pair of side surfaces and the outer peripheral surface. The outer peripheral surface has a tapered surface having an outer diameter increasing from a side of one side surface of the pair of side surfaces of the main body portion toward a side of the other side surface.Type: ApplicationFiled: January 10, 2018Publication date: January 16, 2020Applicant: KABUSHIKI KAISHA RIKENInventors: Hiroshi SHIMIZU, Takayuki YOGUCHI, Takayuki KONDO, Masaaki FUJITA
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Patent number: 10519421Abstract: The present invention aims to provide a method of producing motor neurons/neurons that sufficiently reproduce intrinsic properties of motor neurons/neurons, especially of the motor neurons/neurons in patients, from pluripotent stem cells promptly and synchronically, and a pluripotent stem cell capable of differentiating into a neuron or a motor neuron promptly and synchronically after a drug treatment. A method of generating a motor neuron from a pluripotent stem cell, comprising the following steps in order from (1) to (2): (1) introducing one or more nucleic acids encoding Lhx3, Ngn2, and Isl1 into a pluripotent stem cell; and (2) maintaining expression of the Lhx3, Ngn2, and Isl1 for three days or more.Type: GrantFiled: March 24, 2014Date of Patent: December 31, 2019Assignee: KYOTO UNIVERSITYInventors: Haruhisa Inoue, Keiko Imamura, Takayuki Kondo
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Patent number: 10514009Abstract: A fuel supply device includes a cover member which is attached to an opening of a fuel tank, a pump unit comprising a pump, and a connecting portion for connecting the cover member and the pump unit. The pump unit is connected to the connecting portion so as to be relatively movable to the cover member. When the fuel supply device is attached to the fuel tank, an engagement portion provided at a lower portion of the pump unit abuts the connecting portion such that via the engagement portion the connecting portion presses the pump unit against the fuel tank.Type: GrantFiled: August 10, 2015Date of Patent: December 24, 2019Assignee: AISAN KOGYO KABUSHIKI KAISHAInventors: Tatsuki Fukui, Koji Yoshida, Takuya Kono, Shinya Higashi, Yuichi Murakoshi, Takayuki Kondo, Akihiro Yano, Kensuke Niwa, Hidetomo Ishida
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Publication number: 20190298306Abstract: An acoustic lens contains a base material composed of a diorganopolysiloxane or a silicone rubber compound utilizing a diorganopolysiloxane as a main component, and plate-like inorganic compound particles dispersed in the base material.Type: ApplicationFiled: June 17, 2019Publication date: October 3, 2019Applicant: OLYMPUS CORPORATIONInventors: Takayuki KONDO, Koji KOBAYASHI
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Publication number: 20190250014Abstract: Template matching with an image captured by the first imaging element is performed to obtain a first movement amount in a circumferential direction of the first mark, template matching with an image captured by the second imaging element is performed to obtain a second movement amount in a circumferential direction of the second mark, and a rotation angle is calculated and output by using the first movement amount and the second movement amount.Type: ApplicationFiled: February 14, 2019Publication date: August 15, 2019Inventor: Takayuki KONDO
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Publication number: 20190121323Abstract: An encoder includes a base portion, a scale portion that is provided to be relatively rotatable with respect to the base portion, and has a plurality of marks, an imaging element that is disposed in the base portion, and images the marks, and an estimation portion that performs template matching on a captured image in the imaging element by using a reference image, in which the plurality of marks include a first mark and a second mark, and the estimation portion counts the number of pixels of the imaging element corresponding to a rotation angle of the scale portion with respect to the base portion until a position of the second mark is detected from detection of a position of the first mark, and performs calibration on the basis of the counted number of pixels and the rotation angle.Type: ApplicationFiled: October 23, 2018Publication date: April 25, 2019Inventors: Daiki TOKUSHIMA, Takayuki KONDO
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Patent number: 10266050Abstract: A fuel supply device has a cover member which is attached to an opening portion of a fuel tank and a pump unit comprising a pump. The cover member and pump unit are connected via a connecting portion where the pump unit is rotatably connected to the connecting portion. Further, the fuel supply device includes a fuel residual amount detection device which is attached to the pump unit and configured to detect the residual amount of fuel. The fuel residual amount detection device includes a gauge main body to which electric wirings are connected, an arm portion which is movably mounted relative to the gauge main body and a float which is attached to a leading end of the arm portion. The float is positioned above a lower terminal end of the base portion when the cover member is held and lifted while the pump unit rotates with respect to the connecting portion.Type: GrantFiled: August 10, 2015Date of Patent: April 23, 2019Assignee: AISAN KOGYO KABUSHIKI KAISHAInventors: Takuya Kono, Koji Yoshida, Tatsuki Fukui, Shinya Higashi, Yuichi Murakoshi, Takayuki Kondo, Akihiro Yano, Kensuke Niwa, Hidetomo Ishida
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Patent number: 10252414Abstract: A robot includes a base, a robot arm provided to be turnable around a turning axis with respect to the base, and an encoder including a mark configured to turn around the turning axis according to the turning of the robot arm and an imaging element configured to image the mark, the encoder detecting a state of the turning of the robot arm using a signal output from the imaging element. The encoder includes a telecentric optical system disposed between the imaging element and the mark.Type: GrantFiled: April 18, 2018Date of Patent: April 9, 2019Assignee: Seiko Epson CorporationInventors: Takayuki Kondo, Daiki Tokushima, Hidemitsu Sorimachi
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System for determining robot position having an imaging element to image the mark on a rotatable arm
Patent number: 10252425Abstract: A robot includes a first member, a second member that is provided to be turnable about a turning axis with respect to the first member, marks that are disposed around the turning axis on a surface of the second member, and a mark detection portion that is disposed in the first member and detects the marks.Type: GrantFiled: March 27, 2017Date of Patent: April 9, 2019Assignee: Seiko Epson CorporationInventors: Takayuki Kondo, Daiki Tokushima -
Publication number: 20190099889Abstract: An encoder includes a base portion, a scale portion that is provided to be relatively movable or rotatable with respect to the base portion, and has three or more marks which are different from each other, an imaging element that is disposed in the base portion, and images the marks, and an estimation portion that selects at least one reference image from among three or more reference images, performs template matching on a captured image in the imaging element by using the reference image, so as to detect positions of the marks, and estimates a movement state or a rotation state of the scale portion with respect to the base portion, in which the estimation portion predicts a reference image to be used for post-template matching on the basis of a result of pre-template matching, and performs the post-template matching by using the predicted reference image.Type: ApplicationFiled: September 27, 2018Publication date: April 4, 2019Inventors: Takayuki KONDO, Daiki TOKUSHIMA