Abstract: A solution including a single-stranded nucleic acid (10) having a target base (11) related to SNP or the like is mixed with a solution including two kinds of single-stranded detecting nucleic acids (20a) and (20b) complementary to partial sequences that sandwich the target base (11) between them to hybridize the target nucleic acid (10) and the detecting nucleic acids (20a) and (20b). Thus, a gap part (21) is intentionally formed at a position opposed to the target base (11). Then, a receptor molecule (30) having hydrogen bonding characteristics and fluorescence emitting characteristics is inserted to the gap part (21) as a hydrophobic space. Then, the change of fluorescent strength of the receptor molecule (30) depending on the difference of the target base (11) is detected to detect a single nucleotide substitution.

Abstract: A component mounting structure including a metal base; a first substrate bonded to the upper surface of the metal base; a first wiring pattern formed on the upper surface of the first substrate; a second substrate horizontally mounted on the upper surface of the first substrate so that the lower surface of the second substrate is in contact with the upper surface of the first substrate; a second wiring pattern formed on the second substrate so as to be connected to the first wiring pattern; and a component mounted on the second substrate so as to be connected to the second wiring pattern.