Patents by Inventor Takehisa Iwama
Takehisa Iwama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230383245Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues, without substantially increasing the viscosity of the solution, by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.Type: ApplicationFiled: August 8, 2023Publication date: November 30, 2023Applicant: NISSAN CHEMICAL CORPORATIONInventors: Hisato HAYASHI, Misayo OTANI, Koichiro SARUHASHI, Taito NISHINO, Takehisa IWAMA, Tatsuro KANAKI, Ayako AIHARA
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Patent number: 11771645Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: GrantFiled: September 9, 2021Date of Patent: October 3, 2023Assignees: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Masahiro Goto, Nobuhide Miyachi, Takehisa Iwama, Takayuki Imoto
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Publication number: 20220306985Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the likeType: ApplicationFiled: May 23, 2022Publication date: September 29, 2022Applicants: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Patent number: 11452688Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: GrantFiled: August 28, 2019Date of Patent: September 27, 2022Assignees: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Masahiro Goto, Nobuhide Miyachi, Takehisa Iwama, Takayuki Imoto
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Patent number: 11371013Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: GrantFiled: February 26, 2020Date of Patent: June 28, 2022Assignees: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
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Publication number: 20210401734Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: ApplicationFiled: September 9, 2021Publication date: December 30, 2021Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Masahiro GOTO, Nobuhide MIYACHI, Takehisa IWAMA, Takayuki IMOTO
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Publication number: 20200208101Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the likeType: ApplicationFiled: February 26, 2020Publication date: July 2, 2020Applicants: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito NISHINO, Tatsuro KANAKI, Ayako OTANI, Koichiro SARUHASHI, Misayo Tomura, Takehisa IWAMA, Masato HORIKAWA, Norio NAKATSUJI, Tomomi OTSUJI
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Publication number: 20200095542Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.Type: ApplicationFiled: October 24, 2019Publication date: March 26, 2020Applicant: NISSAN CHEMICAL CORPORATIONInventors: Hisato HAYASHI, Misayo OTANI, Koichiro SARUHASHI, Taito NISHINO, Takehisa IWAMA, Tatsuro KANAKI, Ayako AIHARA
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Patent number: 10590380Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition wherein indeterminate structures are formed in a liquid medium, the structures are uniformly dispersed in the solution and substantially retain the cells and/or tissues without substantially increasing the viscosity of the solution, thus affording an effect of preventing sedimentation thereof, and the like.Type: GrantFiled: March 2, 2017Date of Patent: March 17, 2020Assignees: Nissan Chemical Industries, Ltd., Kyoto UniversityInventors: Taito Nishino, Tatsuro Kanaki, Ayako Otani, Koichiro Saruhashi, Misayo Tomura, Takehisa Iwama, Masato Horikawa, Norio Nakatsuji, Tomomi Otsuji
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Publication number: 20200030217Abstract: A moisturizing base material that contains a lipid peptide compound including at least one of compounds of Formula (1) below and simulated compounds thereof or pharmaceutically usable salts thereof, a surfactant, a specific polyhydric alcohol, a fatty acid, and water. wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; and R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: ApplicationFiled: October 2, 2019Publication date: January 30, 2020Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL CORPORATIONInventors: Masahiro GOTO, Nobuhide MIYACHI, Takehisa IWAMA, Takayuki IMOTO
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Publication number: 20190380949Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: ApplicationFiled: August 28, 2019Publication date: December 19, 2019Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Masahiro GOTO, Nobuhide MIYACHI, Takehisa IWAMA, Takayuki IMOTO
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Patent number: 10487308Abstract: The present invention provides a culture method of cells and/or tissues including culturing cells and/or tissues in a suspended state by using a medium composition having an effect of preventing sedimentation of cells and/or tissues, which is afforded by substantially retaining the cells and/or tissues without substantially increasing the viscosity of the solution by nanofibers which have been added to the solution and uniformly dispersed in the liquid medium, and the like.Type: GrantFiled: January 23, 2015Date of Patent: November 26, 2019Assignee: NISSAN CHEMICAL CORPORATIONInventors: Hisato Hayashi, Misayo Otani, Koichiro Saruhashi, Taito Nishino, Takehisa Iwama, Tatsuro Kanaki, Ayako Aihara
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Patent number: 10421055Abstract: There is provided a dispersion containing a lipid peptide type compound useful as a low molecular weight gelator and a solvent capable of dissolving the lipid peptide type compound at a lower temperature. There is provided also a dispersion from which a hydrogel can be formed by a simpler method and from which a gel can be obtained as a gel having high thermal stability, and provide a method for forming the gel. A dispersion including a lipid peptide type compound in which a peptide portion having an amino acid repeating bonding structure is bonded to a lipid portion consisting of a C9-23 aliphatic group; and at least one alcohol selected from the group consisting of 1,2-alkanediol, 1,3-alkanediol, and ethylene glycol monoalkyl ether or a mixed solution of the at least one alcohol and water; and a method for producing a hydrogel by use of the dispersion.Type: GrantFiled: June 25, 2013Date of Patent: September 24, 2019Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Takayuki Imoto, Takehisa Iwama
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Patent number: 10316292Abstract: A culture method (a preservation method) of somatic stem cells does not use a chemical such as DMSO that affects a differentiation function of somatic stem cells. A material for an undifferentiated state-maintaining culture for a somatic stem cell, having a naturally occurring polysaccharide; a culture liquid in which the material for the undifferentiated state-maintaining culture is dispersed; a somatic stem cell-containing culture liquid in which the somatic stem cell is suspended in the culture liquid; and a culture method for mesenchymal stem cells in which a naturally occurring polysaccharide is used.Type: GrantFiled: January 23, 2015Date of Patent: June 11, 2019Assignees: NISSAN CHEMICAL INDUSTRIES, LTD., KYUSHU UNIVERSITYInventors: Satoru Kidoaki, Yukie Tuji, Hisato Hayashi, Takehisa Iwama, Masato Horikawa
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Publication number: 20190053988Abstract: Described are a method for producing cellulose fibers suitable for use in a thickening composition, a method for producing a thickening composition that contains the cellulose fibers, and a method for thickening a composition. The method for producing the cellulose fibers includes grinding a composition containing cellulose fibers and an aqueous solution to produce a dispersion containing cellulose fibers having an average fiber diameter (D) in a range of from 0.001 to 100 ?m in the aqueous solution.Type: ApplicationFiled: October 22, 2018Publication date: February 21, 2019Inventors: Hisato HAYASHI, Takehisa IWAMA
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Publication number: 20190030166Abstract: The invention relates to a method for enhancing percutaneous absorbability of a water-soluble drug. The invention provides a complex formed by a water-soluble effective ingredient and a fat-soluble compound having an aldehyde group through an interaction which can be dissociated in water; a percutaneously absorbable composition comprising the complex, a percutaneous absorption controller and a fat-soluble medium; and a method for controlling release of the water-soluble effective ingredient from the complex in the skin.Type: ApplicationFiled: January 27, 2017Publication date: January 31, 2019Applicants: NISSAN CHEMICAL CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Fumiyasu ONO, Masahiro GOTO, Osamu HIRATA, Takehisa IWAMA
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Patent number: 10017805Abstract: The present invention relates to a protein production accelerating agent that has enabled to largely increase the produced amount of a desired protein by adding polysaccharides to a medium for animal cells containing a serum or serum alternative, and a production method of a protein using a medium containing the protein production accelerating agent.Type: GrantFiled: August 23, 2013Date of Patent: July 10, 2018Assignees: Nissan Chemical Industries, Ltd., Institute of National Colleges of Tehcnology, JapanInventors: Misayo Tomura, Takehisa Iwama, Koichiro Saruhashi, Taito Nishino, Masato Horikawa, Hiroharu Kawahara
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Publication number: 20180185414Abstract: The objective of the present invention is to provide a calcium salt composition with improved dispersity and preservation stability of calcium salt in an aqueous medium as well as with increased filaggrin production promoting action of calcium salt in addition. The present invention relates to a calcium salt composition comprising a calcium salt insoluble or poorly soluble to an aqueous medium and an anionic dispersant.Type: ApplicationFiled: June 10, 2016Publication date: July 5, 2018Applicant: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Osamu HIRATA, Takehisa IWAMA
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Patent number: 10010490Abstract: There is provided a cosmetic additive in which the cosmetic obtained by mixing has excellent transparency, and good spread and feeling of use during application, and stickiness when dried can be suppressed, and a cosmetic containing the additive. A cosmetic additive containing cellulose fibers having an average fiber diameter (D) of 0.001 to 0.05 ?m, and a ratio (L/D) of average fiber length (L) to average fiber diameter (D) of 5 to 500; and a cosmetic containing the cosmetic additive.Type: GrantFiled: December 4, 2013Date of Patent: July 3, 2018Assignee: NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Hisato Hayashi, Takehisa Iwama
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Publication number: 20180021250Abstract: A transdermally absorbable base material including: a lipid peptide compound including at least one of compound of Formula (1) below and the similar compounds or pharmaceutically usable salts thereof; a surfactant; a specific polyhydric alcohol; a fatty acid; and water, wherein R1 is a C9-23 aliphatic group; R2 is a hydrogen atom or a C1-4 alkyl group that optionally has a branched chain having a carbon atom number of 1 or 2; R3 is a —(CH2)n—X group; n is a number of 1 to 4; and X is amino group, guanidino group, —CONH2 group, or a 5-membered cyclic group optionally having 1 to 3 nitrogen atoms, a 6-membered cyclic group optionally having 1 to 3 nitrogen atoms, or a condensed heterocyclic group constituted by a 5-membered cyclic group and a 6-membered cyclic group which optionally have 1 to 3 nitrogen atoms.Type: ApplicationFiled: January 28, 2016Publication date: January 25, 2018Applicants: KYUSHU UNIVERSITY, NISSAN CHEMICAL INDUSTRIES, LTD.Inventors: Masahiro GOTO, Nobuhide MIYACHI, Takehisa IWAMA, Takayuki IMOTO