Patents by Inventor Takena Mochizuki

Takena Mochizuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for separation of immunoglobulin monomers
    Patent number: 8741600
    Abstract: A method of accurately separating immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates to cross-flow filtration using an ultrafiltration membrane, an ultrafiltration membrane module, and a cross-flow filtration apparatus. The method can separate immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates and having an immunoglobulin concentration of 1 to 150 g/L to cross-flow filtration using an ultrafiltration membrane having a molecular weight cut-off of 100,000 or more and less than 500,000 so that immunoglobulin monomers passes through the ultrafiltration membrane with a permeability of 80% or more while achieving a fractionation performance in which the permeability ratio of immunoglobulin dimers to immunoglobulin monomers that pass through the ultrafiltration membrane is 0.20 or less.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: June 3, 2014
    Assignee: Asahi Kasei Kabushiki Kaisha
    Inventors: Fumihiko Yamaguchi, Hitoshi Mizomoto, Shinya Hamasaki, Takena Mochizuki
  • METHOD FOR SEPARATION OF IMMUNOGLOBULIN MONOMERS
    Publication number: 20100190965
    Abstract: A method of accurately separating immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates to cross-flow filtration using an ultrafiltration membrane, an ultrafiltration membrane module, and a cross-flow filtration apparatus. The method can separate immunoglobulin monomers by subjecting an immunoglobulin solution containing at least immunoglobulin monomers and immunoglobulin aggregates and having an immunoglobulin concentration of 1 to 150 g/L to cross-flow filtration using an ultrafiltration membrane having a molecular weight cut-off of 100,000 or more and less than 500,000 so that immunoglobulin monomers passes through the ultrafiltration membrane with a permeability of 80% or more while achieving a fractionation performance in which the permeability ratio of immunoglobulin dimers to immunoglobulin monomers that pass through the ultrafiltration membrane is 0.20 or less.
    Type: Application
    Filed: June 18, 2008
    Publication date: July 29, 2010
    Applicant: Asahi Kasei Kabushiki Kaisha
    Inventors: Fumihiko Yamaguchi, Hitoshi Mizomoto, Shinya Hamasaki, Takena Mochizuki