Abstract: The purpose of the present invention is to provide a novel stereoselective method for preparing a cyclic dinucleotide derivative and a production intermediate therefor, which can be used for an antibody-immunostimulant conjugate. Also provided is a method for producing a cyclic dinucleotide-linker and an antibody-immunostimulant conjugate while using the above production method. Further provided is a method for preparing a cyclic dinucleotide derivative, the method including the step of subjecting a compound (I) and a compound (IV) to stereoselective condensation using an optically active phosphitylating agent (Rc-II) or (Sc-II).

Abstract: Provided is a particle material that achieves excellent mechanical properties and optical properties when dispersed in a transparent resin material in order to solve the problem. In a case where primary particles having particle sizes in a certain range are formed into an aggregate, mechanical properties are enhanced while optical properties are maintained. The primary particles each have compositions different between the inside thereof and the surface thereof. Therefore, the optical properties to be obtained are easily controlled unlike an inorganic substance in which both of the compositions are mixed at an atomic level. The particle material of the present invention is an aggregate including primary particles in which a specific surface area. diameter is not less than 0.8 nm and not greater than 80 nm, the primary particles formed of an inorganic substance in which a composition of a surface and a composition of an inside are different.

Abstract: Provided is an oil leakage repairing material, wherein the oil leakage repairing material is a curable composition, oil absorption of the oil leakage repairing material before curing is 100% or greater, and oil absorption of the oil leakage repairing material after curing is 50% or less.

Abstract: An advanced map DB 43 stored on a server device 4 includes pulse type information that is configuration information for detecting a landmark using a LIDAR 2. By sending request information D1 including own vehicle position information, the vehicle mounted device 1 receives response information D2 including pulse type information corresponding to a landmark around the own vehicle position and controls the LIDAR 2 on the basis of the received pulse type information.

Abstract: A vehicle power supply system includes a power source control device that executes a process of switching a connection state of a driving circuit to the main power source and an auxiliary power source including; a process of switching the connection state so as to transition to a backup state as a voltage decrease of the main power source occurs, and a process of switching the connection state so as to transition to a normal state as the voltage decrease of the main power source is resolved. After a voltage decrease of the main power source occurs, a turning-side control device of a steering control unit sets an output-limited state for a turning-side motor. The output-limited state is canceled upon the power source control device completing switching of the connection state so as to transition.

Abstract: A light-emitting device includes: a light source that radiates primary light; and a first phosphor that absorbs the primary light and converts the primary light into first wavelength-converted light having a longer wavelength than the primary light, wherein the primary light is laser light, the first wavelength-converted light includes fluorescence based on electron energy transition of Cr3+, and a fluorescence spectrum of the first wavelength-converted light has a maximum fluorescence intensity value in region of a wavelength exceeding 710 nm.

Abstract: A vehicle article storage structure includes an article storage box (13) provided with an opening (33a) on the upper side forgetting articles in and out, a housing unit (15) provided on the lower side of an instrument panel (3) to house the article storage box (13), and links (35, 37, and 39) configured to movably support the article storage box (13) along a range from a housed position at which the article storage box (13) is housed in the housing unit (15) to a drawn position at which the article storage box (13) is drawn in a vehicle compartment rearward direction from the housed position via an intermediate position at which the article storage box (13) is located between the housed position and the drawn position, the intermediate position being located below the housed position and the drawn position.

Abstract: Disclosed herein is a coil component that includes a coil part embedded in a magnetic element body. The coil part has a structure in which plural interlayer insulating films and plural conductor layers having a coil pattern are alternately stacked. At least one of the conductor layers has a clearance area having no coil pattern and extending radially outward from a center axis of the coil part. The magnetic element body includes a first magnetic resin layer provided in an inner diameter area of the coil part, a second magnetic resin layer provided in a radially outside area of the coil part, and a fifth magnetic resin layer filled in the clearance area and contacting the first and second magnetic resin layers.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A method for manufacturing a glass panel unit includes an assembling step, a bonding step, a gas exhausting step, a sealing step, and an activating step. The bonding step includes melting a peripheral wall in a baking furnace at a first predetermined temperature to hermetically bond a first glass pane and a second glass pane together with the peripheral wall thus melted. The gas exhausting step includes exhausting a gas from an internal space through an exhaust port in the baking furnace to turn the internal space into a vacuum space. The sealing step includes locally heating to a temperature higher than a second predetermined temperature, and thereby melting, either a port sealing material or an exhaust pipe to seal the exhaust port and thereby obtain a work in progress. The activating step includes activating a gas adsorbent after the sealing step to obtain a glass panel unit.

Abstract: A pillar delivery method is a method for delivering a plurality of pillars onto a substrate, including a glass panel, to manufacture a glass panel unit. The pillar delivery method includes an irradiation step, a holding step, and a mounting step. The irradiation step includes setting, over a holder, a sheet for use to form pillars and irradiating the sheet with a laser beam to punch out the plurality of pillars. The holding step includes having the plurality of pillars, which have been punched out of the sheet, held by the holder. The mounting step includes picking up some or all of the plurality of pillars from the holder and mounting the pillars onto the substrate.

Abstract: In a projection system, a light source unit emits a first visible light beam, a second visible light beam having a longer wavelength than the first visible light beam, and a near infrared light beam. A spatial light modulation unit subjects the first visible light beam, the second visible light beam, and the near infrared light beam, all emitted from the light source unit, to spatial light modulation to produce a first image light beam, a second image light beam, and a third image light beam, respectively. A controller makes a projection optical system not only selectively project any one of a plurality of image light beams, including the first image light beam, the second image light beam, and the third image light beam, but also selectively project any two or more of the plurality of image light beams, by controlling the spatial light modulation unit in two different manners.

Abstract: A light source device includes a connector, a light source, a lever member, and a detector. The connector allows the light guide member to be detachably connected thereto. The light source emits light to be incident on the light guide member connected to the connector. The lever member is displaced depending on presence or absence of the connection of the light guide member to the connector. The detector detects the displacement of the lever member and outputs a detection result.

Abstract: An endoscope system includes: an insertion component which includes a base end and a tip end, and is inserted into a subject at least up to the tip end; a light source which emits first light and second light having a hue different from a hue of the first light a light sensor; and a controller, the insertion component includes: a first light guide member which emits the first light and the second light from the tip end as illumination light; and a second light guide member which guides reflected light of the illumination light emitted from the tip end, the light sensor receives the reflected light guided by the second light guide member, and the controller controls the light source based on the intensity of the reflected light received by the light sensor to stop emission of the at least one of the first light or the second light.

Abstract: A fixing device that fixes a lower end portion of a suspension belt to a holding portion is provided with a shaft-like portion with an axial direction aligned with a horizontal direction; a fixing portion where the lower end portion of the suspension belt is fixed is provided on an outer circumferential surface of the shaft-like portion; a region of the outer circumferential surface on one side of a virtual vertical surface that runs through an axial center of the shaft-like portion is defined as a first region and a region of the outer circumferential surface on the other side of the virtual vertical surface is defined as a second region; the fixing portion is provided in the first region; and the suspension belt extending from the fixing portion is disposed running through a lowest portion of the outer circumferential surface and running along the second region and upward.

Abstract: In an article transport vehicle that is able to transport a plurality of types of articles, the efficiency of operations is improved in accordance with the type of article, while suppressing an increase in the size of the article transport vehicle. If a control device determines that an article held by a holding portion is a first-type article, the control device controls the transfer mechanism so as to cause the turning mechanism to perform a turning mechanism and cause a sliding mechanism to perform a sliding operation such that operation periods of these operations do not overlap. If the control device determines that the article held by the holding portion is a second-type article, the control device controls the transfer mechanism so as to perform the turning operation and the sliding operation such that the operation periods of these operations overlap.

Abstract: The disclosure provides a vehicle body capable of suppressing the occurrence of cracks in a center pillar at the time of a side collision. A center pillar stiffener forms a hollow structure with a closed cross section by including a side wall which faces the outer surface of a pillar inner, a front wall which is formed by bending from a front end of the side wall to form a first ridge with the side wall and which is joined to the outer surface of the pillar inner, and a rear wall which is formed by bending from a rear end of the side wall to form a second ridge with the side wall and which is joined to the outer surface of the pillar inner. The pillar stiffener is provided with a bead recessed toward the pillar inner and orthogonal to the first and second ridges.

Abstract: A light emitting device (1) is a light emitting device for use in a photodynamic therapy. The light emitting device includes: a solid-state light-emitting element (2) that emits primary light in which an energy density is 0.5 W/mm2 or more; and a wavelength converter (3) including a first phosphor (4) that emits first wavelength-converted light (7). The first wavelength-converted light has a light component across at least a whole of a wavelength range of 700 nm or more and less than 800 nm. Energy of fluorescence emitted from the wavelength converter is 100 mW or more. A medical device includes the light emitting device.

Abstract: The disclosure provides a vehicle side structure. The vehicle side structure is for being mounted near a door, and includes: an electric motor disposed inside the door to drive a door glass up and down; a fitting member, fitting the door and a vehicle body; and a connecting member, connecting the fitting member and the electric motor.

Abstract: A wavelength converter 100 includes: a first phosphor 1 composed of an inorganic phosphor activated by Ce3+; and a second phosphor 2 composed of an inorganic phosphor activated by Ce3+ and different from the first phosphor. At least one of the first phosphor and the second phosphor is particulate. The first phosphor and the second phosphor are bonded to each other by at least one of a chemical reaction in a contact portion between the compound that constitutes the first phosphor and a compound that constitutes the second phosphor and of adhesion between the compound that constitutes the first phosphor and the compound that constitutes the second phosphor.