Abstract: An illumination device includes a light source, a first optical member, and a fixing portion. The first optical member includes a light reflection portion configured to reflect light, at least a part of the light reflection portion overlapping with the light source, and a light transmitting portion configured to transmit light, the light transmitting portion not overlapping the light reflection portion. A center of the light source in a plan view is defined as a first center, and a center of the light reflection portion in a plan view is defined as a second center. In the light reflection portion, the second center is located between the fixing portion and the first center at a first temperature, and at a second temperature higher than the first temperature, a position of the second center is closer to the first center than a position of the second center at the first temperature.

Abstract: An organic EL device includes an emitting region provided between a cathode and an anode, a first anode-side-organic layer, a second anode-side-organic layer, and a third anode-side-organic layer, in which the emitting region includes at least a first emitting layer, the first anode-side-organic layer is in direct contact with the second anode-side-organic layer, the second anode-side-organic layer is in direct contact with the third anode-side-organic layer, the third anode-side-organic layer has a film thickness of 20 nm or more, the second anode-side-organic layer contains at least one compound different from a compound contained in the third anode-side-organic layer, the first emitting layer is a fluorescent emitting layer, and a refractive index NM2 of a constituent material contained in the second anode-side-organic layer and a refractive index NM3 of a constituent material contained in the third anode-side-organic layer satisfy a relationship of Numerical Formula NM, NM2>NM3??(Numerical Formula NM

Abstract: An organic electroluminescence device includes an emitting region between a cathode and an anode, a first anode side organic layer, and a second anode side organic layer. The emitting region includes at least a first emitting layer, the first anode side organic layer is in direct contact with the second anode side organic layer, the first anode side organic layer contains first and second organic materials, a content of the first organic material in the first anode side organic layer is less than 50 mass %, the second anode side organic layer contains a second hole transporting zone material, the first emitting layer is an emitting layer that emits fluorescence, and a refractive index NM1 of the constituent materials contained in the first anode side organic layer and a refractive index NM2 of the constituent material contained in the second anode side organic layer satisfy a relationship of NM1>NM2.

Abstract: The present invention establishes a molecular therapy for glycogen storage disease type Ia. The present invention provides an oligonucleotide of 15-30 bases comprising a nucleotide sequence complementary to die cDNA of G6PC gene with c.648G>T mutation, wherein the oligonucleotide comprises a sequence complementary to a region comprising any site between the 82nd to the 92nd nucleotide from the 5? end of exon 5 of the G6PC gene with c.648C>T mutation, a pharmacologically acceptable salt or solvate thereof. Also provided is a pharmaceutical drug comprising the oligonucleotide, a pharmacologically acceptable salt or solvate thereof (e.g., therapeutic drug for glycogen storage disease type Ia).

Abstract: A display control device has display setting information including setting information of a layer structure of display objects on a terminal screen and setting information of a group to which the display objects belong, display state information indicating a display state of the display object, and operation setting information defining which setting content a combination of an operation target and operation content on a screen indicate for a layer structure and a group of display objects for each combination of the operation target and the operation content. The display control device specifies the setting content to the display object based on the combination of the operation target and the operation content, the display state information, and the operation setting information when an operation on the display object occurs.

Abstract: Provided are a photon up-conversion film, which is capable, of high-efficiency up-conversion even in air and even when low-intensity light is used, and a simple method of producing the film. The photon up-conversion film according to one embodiment of the present invention includes: a matrix including a resin; and a pore portion, wherein the photon up-conversion film includes at least a sensitizing component capable of absorbing light in a first wavelength region ?1, and a light-emitting component capable of radiating light in a second wavelength region ?2 including wavelengths shorter than those of the first wavelength region ?1, and wherein the sensitizing component and the light-emitting component are present at an interface between the matrix and the pore portion.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: A photoelectric conversion apparatus includes a pixel array having a plurality of column signal lines which are divided into a plurality of groups, a readout circuit configured to read out signals from the pixel array via the plurality of column signal lines. A holding unit includes one first region and a plurality of second regions. A plurality of first correction values respectively corresponding to the plurality of columns are stored in the first region. Each second region is associated with a readout condition for reading signals from each pixel unit of the pixel array by the readout circuit, and a plurality of second correction values respectively corresponding to the plurality of groups are stored in each second region.

Abstract: Photoelectric conversion apparatus includes read circuit for reading signals of pixel array, and signal processing unit for generating pixel signal by performing CDS on signals read by the read circuit and performing shading correction on the pixel signal. The read circuit has function of reading signal of the pixel array with first and second gain. The read circuit reads noise level with the first gain and reads optical signal level with the first or second gain from selected effective pixel for the correlated double sampling. In the shading correction, pixel signal of effective pixel from which optical signal level has been read with the first gain is corrected based on first correction value, and pixel signal of effective pixel from which optical signal level has been read with the second gain is corrected based on second correction value.

Abstract: A display device includes a display panel that includes a first hole and a device housing that is configured such that the display panel is fastened and fixed to the device housing by a screw passed through the first hole and screwed into the screw hole. The display panel includes a display-side positioning part which is configured to fit to a portion of the device housing to perform positioning of the display panel with respect to the device housing and which includes the first hole, and the device housing includes a housing-side positioning part which is configured to fit to the display-side positioning part to perform the positioning and which includes a second hole formed so as to communicate with the first hole when the housing-side positioning part is fitted to the display-side positioning part.

Abstract: A second main surface of the copper plate is opposite a first main surface of the copper plate, and is bonded to a silicon nitride ceramic substrate by the bonding layer. A first portion and a second portion of an end surface of the copper plate form an angle of 135° to 165° on an outside of the copper plate. An extended plane of the first portion and the second main surface form an angle of 110° to 145° a side where the second portion is located. A distance from the second main surface to an intersection of the first portion and the second portion in a direction of a thickness of the copper plate is 10 to 100 ?m. The second main surface extends beyond the extended plane of the first portion by a distance of 10 ?m or more.

Abstract: [PROBLEM] An object of the present invention is to provide a nonvolatile memory device having an excellent information retention characteristic, exhibiting high performance, and achieving practical mass-production, and a manufacturing method therefor. [SOLUTION] A nonvolatile memory device 1 has a laminated structure part including a plurality of Al2O3 layers 4 and a plurality of SiO2 layers 6 formed as two types of insulating layers formed with different compositions and disposed alternately, and an O-M1-O layer 5 of a 0.5 molecular layer to a 2.0 molecular layer, formed by a chemical bond between a metal element M1 and oxygen, and disposed on each joining interface between the insulating layers, the metal element M1 being an element other than elements constituting the insulating layers, and the nonvolatile memory device stores information by modulating an interface dipole induced in the vicinity of the O-M1-O layer 5 by external electrical stimulation.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La—(CH2)n2—C(?O)—wherein the anti-HER2 antibody is connected to the terminal L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2—C(?O)— moiety with the nitrogen atom of the amino group at position 1 as the connecting position.

Abstract: An acquisition unit acquires image data by performing screen capture of a screen operated by a user, at a predetermined interval. A detection unit detects the user operation. An estimation unit estimates an amount of delay time from a user operation time point to a time point at which the user operation is detected by the detection unit. The selection unit selects image data of the user operation time point out of the acquired image data.

Abstract: A peripheral information acquisition unit (121) acquires information relating to a first application (13a) running in a terminal, information relating to control of the terminal, or information that can be acquired from a sensor included in the terminal, as peripheral information. The peripheral information acquired by the peripheral information acquisition unit (121) is accumulated in a peripheral information accumulation unit (122). A dialogue interface unit (11) accepts input of information from a user and outputs information to the user. When the peripheral information accumulated in the peripheral information accumulation unit (122) and information input to the dialogue interface unit (11) satisfy a predetermined condition, a scenario control unit (123) causes the dialogue interface unit (11) to output information relating to execution of a second application (14) that is associated with the condition in advance.

Abstract: Provided is a lighting device capable of forming an optimal light distribution pattern in a situation in which vehicle travel is being automatically controlled. Provided is a lighting device (100) in which a region having the highest luminous intensity on a virtual projection plane (VP) when the virtual projection plane (VP) is divided into three equal parts from lowest to highest luminous intensity is isolated in the left and right directions by a V line, and at least a portion of the region having the highest luminous intensity is located in a first central portion (M1) of the virtual projection plane (VP).

Abstract: A magnet structure includes a first sintered magnet, a second sintered magnet, and an intermediate layer disposed between the first sintered magnet and the second sintered magnet. Each of the first sintered magnet and the second sintered magnet independently includes crystal grains containing a rare earth element, a transition metal element, and boron. The intermediate layer contains rare earth element oxide phases and crystal grains containing a rare earth element, transition metal element, and boron. Each of the transition metal elements independently includes Fe or a combination of Fe and Co. An average coverage factor of the rare earth element oxide phases measured on the basis of a cross section perpendicular to the intermediate layer of the magnet structure is within a range of 10% to 69%.

Abstract: A lighting device includes a circuit substrate that includes a wiring circuit, LEDs that are mounted on the circuit substrate and that emit primary light, a phosphor sheet that faces a light emission surface of each of the LEDs and that has a function of converting part of the primary light into secondary light in another wavelength range that differs from the wavelength range, and a selective reflection layer that is composed of dielectric multilayer film, that is disposed between the phosphor sheet and the LEDs, that covers the light emission surface of each of the LEDs, that allows the part of the primary light to be transmitted therethrough, and that reflects part of the secondary light. The selective reflection layer is disposed so as to have convex shapes projecting in a direction opposite a direction toward the circuit substrate in regions that overlap the LEDs.

Abstract: A timeline display device includes processing circuitry configured to store event data for displaying a figure that represents an operation along a time axis, the event data including a start time point and an end time point of the operation, acquire a search condition that specifies an appearance pattern of the figure that is displayed, and search for data pieces of the event data that match the acquired search condition.

Abstract: A display control device acquires event data, that is, data expressed as a set of fixed units of data, and uses the acquired event data to display an image of the event data visualized according to a predetermined visualization method. Additionally, in the case of receiving an operation of attaching an electronic label to the displayed image, the display control device stores information about the electronic label, the event data, and setting information related to the image when the electronic label was attached in association with each other in storage. Also, in the case of receiving the specification of an electronic label to be restored from among the electronic labels, the display control device acquires the data of the electronic label as well as the event data and setting information associated with the electronic label from the storage, and restores the image with the electronic label attached.