Abstract: The present invention establishes a molecular therapy for glycogen storage disease type Ia. The present invention provides an oligonucleotide of 15-30 bases comprising a nucleotide sequence complementary to die cDNA of G6PC gene with c.648G>T mutation, wherein the oligonucleotide comprises a sequence complementary to a region comprising any site between the 82nd to the 92nd nucleotide from the 5? end of exon 5 of the G6PC gene with c.648C>T mutation, a pharmacologically acceptable salt or solvate thereof. Also provided is a pharmaceutical drug comprising the oligonucleotide, a pharmacologically acceptable salt or solvate thereof (e.g., therapeutic drug for glycogen storage disease type Ia).

Abstract: A rotor includes stacked core plates, a hole, and a magnet inserted into the hole. A holding core plate has a through hole as part of the hole, a protrusion protruding inwardly from an inner surface of the through hole and being in contact with the magnet, and a displacement permission portion located in an opposite direction to a protrusion direction of the protrusion and permitting displacement of the protrusion in the opposite direction. The rotor includes at least one of a magnet-side chamfered portion in which the front side edge portion of the magnet is chamfered or a protrusion-side chamfered portion in which the tip end edge portion of the protrusion is chamfered. A sum of lengths of the magnet-side and protrusion-side chamfered portions is equal to or longer than a length of the protrusion in the protrusion direction as the rotor is viewed from the axial direction.

Abstract: A rotor includes core plates, a hole, and a magnet in the hole. The core plates include a first core plate and a second core plate frontward of the first core plate. The first core plate includes a first hole, a first protrusion protruding inward of the first hole, and a first portion located in an opposite direction to a protrusion direction of the first protrusion as viewed from the axial direction and permitting deformation of the first protrusion in the opposite direction. The second core plate includes a second hole, and at least one of a recess recessed in the opposite direction and overlapping the first protrusion as viewed in the axial direction, or a second portion located in the opposite direction with respect to the first protrusion as viewed in the axial direction and permitting deformation of an inner surface of the second hole in the opposite direction.

Abstract: An object of the present invention is to provide an apparatus for injecting carbon dioxide into underground capable of capturing carbon dioxide from the atmosphere and injecting it into underground in a harmless state and at a low cost, the apparatus including: a capturing unit configured to concentrate carbon dioxide directly from the atmosphere and capture concentrated carbon dioxide as a mixture gas; and an injection well connected to the capturing unit for pressurizing the mixture gas and injecting the mixture gas into an underground reservoir, in which the capturing unit adjusts a proportion of carbon dioxide in the mixture gas to 25% by volume or more.

Abstract: The present invention pertains to a friction transmission belt that includes a core cable. The core cable includes a cord comprising: a core yarn containing high elastic-modulus fibers; and a plurality of sheath yarns that are disposed around the core yarn and that contain low elastic-modulus fibers. The cord is twisted and the proportion of the average diameter of the sheath yarn to the average diameter of the core yarn is 0.2 to 0.4.

Abstract: A turbocharger includes: a bearing; a casing for accommodating the bearing; and a first thermometer including a first temperature sensor for measuring temperature of lubricant oil. The casing includes a lubricant oil discharge part having a lubricant oil outlet for discharging the lubricant oil from the turbocharger. The lubricant oil discharge part includes a lubricant oil storage part for storing the lubricant oil. The first temperature sensor is disposed in the lubricant oil storage part.

Abstract: A medical instrument display includes an image storage that stores a plurality of image data of a medical instrument, a data analyzer that searches a plurality of image data stored in the image storage on a certain condition, and a display controller that causes a display to display a first medical instrument image that has been selected from thumbnail images, the thumbnail images being based on a plurality of the image data obtained by the search, and a second medical instrument image in good order, the second medical instrument image being different from the first medical instrument image.

Abstract: A medical instrument display includes an image storage that stores a plurality of image data of a medical instrument, a data analyzer that searches a plurality of image data stored in the image storage on a certain condition, and a display controller that causes a display to display a first medical instrument image that has been selected from thumbnail images, the thumbnail images being based on a plurality of the image data obtained by the search, and a second medical instrument image in good order, the second medical instrument image being different from the first medical instrument image.

Abstract: A medical instrument display includes an image storage that stores a plurality of image data of a medical instrument, a data analyzer that searches a plurality of image data stored in the image storage on a certain condition, and a display controller that causes a display to display a first medical instrument image that has been selected from thumbnail images, the thumbnail images being based on a plurality of the image data obtained by the search, and a second medical instrument image in good order, the second medical instrument image being different from the first medical instrument image.

Abstract: A contact vibration detection device 100 for detecting contact vibration due to contact between a rotational shaft 12 and a stationary part 13 includes: a rotation waveform determination unit 101 configured to determine a rotation waveform of the rotational shaft 12 based on displacement of the rotational shaft 12 during rotation; a parameter change detection unit 102 configured to detect a change in a parameter of at least one of an effective value of the rotation waveform or a phase angle of the rotation waveform; and a contact vibration determination unit 103 configured to determine whether the contact vibration occurs based on presence or absence of the change in the parameter.

Abstract: Provided is an electric-assist supercharger configured such that a motor (30) is attached to the end portion of a rotor shaft (15) close to a silencer (26), the rotor shaft (15) being connected to a compressor portion. Such a supercharger includes a suction air introduction path (24) formed in the silencer 26 such that a main suction air flow flows in the radial direction of the silencer (26) toward a connection portion between the silencer (26) and the compressor portion, and a cooling air intake path (40) formed in the silencer (26) in which at least an outlet thereof is on the center axis of the rotor shaft (15).

Abstract: A thermo-sensitive draw solute including a polyoxyalkylene adduct represented by a general formula (1): R1O(AO)nR2 (1), where R1 denotes a residue after withdrawal of a hydroxy group from a monovalent alcohol having a carbon number ranging from 6 to 13, R2 denotes a hydrogen atom or denotes an alkyl group or an alkenyl group having a carbon number ranging from 1 to 13, AO denotes an oxyalkylene group having a carbon number ranging from 2 to 4, n denotes an average added mole number of an alkylene oxide ranging from 1 to 235, and where n is two or more, the two or more AOs may be the same or different from each other.

Abstract: A turbocharger includes: a suction part (10b) configured to suction a fluid; an impeller (12) configured to compress the fluid supplied from the suction part (10b); a drive shaft (18) having one end to which the impeller (12) is attached; an intermediate shaft (16) provided at the one end of the drive shaft (18) such that the drive shaft (18) extends in an axial direction from a downstream side to an upstream side of the impeller (12); a motor (14) or a generator having a rotor (14a) attached to a distal end of the intermediate shaft (16) via a coupling (20a), a stator (14c) provided so as to correspond to the rotor (14a), and a body portion (14b) configured to hold the stator (14c); and a cover (30) formed into a tubular shape to surround the intermediate shaft (16) and the coupling (20a).

Abstract: A water treatment apparatus including: a forward osmosis device configured to allow a diluted draw solution to flow out and to discharge a water-containing solution; a heater configured to heat the diluted draw solution; a water separator configured to separate the diluted draw solution heated by the heater into a water-rich solution and the draw solution having water content lower than that of the water-rich solution; a cooler configured to cool a liquid and allow the liquid to flow out as a coolant; an inflow side heat exchanger configured to perform heat exchange between the coolant flowed out from the cooler and the draw solution flowed out from the water separator; and an outflow side heat exchanger configured to perform heat exchange between the diluted draw solution flowed out from the forward osmosis device and the water-rich solution flowed out from the water separator.

Abstract: The present invention pertains to a friction transmission belt that includes a core cable. The core cable includes a cord comprising: a core yarn containing high elastic-modulus fibers; and a plurality of sheath yarns that are disposed around the core yarn and that contain low elastic-modulus fibers. The cord is twisted and the proportion of the average diameter of the sheath yarn to the average diameter of the core yarn is 0.2 to 0.4.

Abstract: A medical tool work support system, a medical tool work support method, and a medical tool work support program alleviate a workload on a user. The medical tool work support system includes a display, a memory that stores data indicating a work procedure on a medical tool in a work step to be performed for surgery using the medical tool, and a display controller that causes the display to display the work procedure based on the data stored in the memory.

Abstract: A thermo-sensitive water absorbent is used as a draw material in production of fresh water by a forward osmosis process. The thermo-sensitive water absorbent has a cloud point, and coagulates when heated, the thereto-sensitive water absorbent being a block copolymer containing at least a hydrophobic part and a hydrophilic part, having a glycerin structure as a basic structure, and including an ethylene oxide group and a group consisting of propylene oxide and/or butylene oxide.

Abstract: A thermo-sensitive water absorbent is used as a draw material in production of fresh water by a forward osmosis process. The thermo-sensitive water absorbent has a cloud point, and coagulates when heated, the thermo-sensitive water absorbent being a block copolymer containing at least a hydrophobic part and a hydrophilic part, having a glycerin structure as a basic structure, and including an ethylene oxide group and a group consisting of propylene oxide and/or butylene oxide.

Abstract: A thermo-sensitive water absorbent is used as a draw material in production of fresh water by a forward osmosis process. The thermo-sensitive water absorbent has a cloud point, and coagulates when heated, the thermo-sensitive water absorbent being a block copolymer containing at least a hydrophobic part and a hydrophilic part, having a glycerin structure as a basic structure, and including an ethylene oxide group and a group consisting of propylene oxide and/or butylene oxide.

Abstract: A contact vibration detection device 100 for detecting contact vibration due to contact between a rotational shaft 12 and a stationary part 13 includes: a rotation waveform determination unit 101 configured to determine a rotation waveform of the rotational shaft 12 based on displacement of the rotational shaft 12 during rotation; a parameter change detection unit 102 configured to detect a change in a parameter of at least one of an effective value of the rotation waveform or a phase angle of the rotation waveform; and a contact vibration determination unit 103 configured to determine whether the contact vibration occurs based on presence or absence of the change in the parameter.