Abstract: Provided is a particle beam therapeutic device, a particle beam therapeutic system, an irradiation planning device, and a particle beam irradiation method. In a particle beam therapeutic system 1, while a magnetic field generation device 9 generates a magnetic field that affects a particle beam in the vicinity of a target of a subject, a particle beam extracted from an ion source 2 is accelerated by an accelerator 4, transported by a beam transport system 5, and applied from an irradiation device 6. In the irradiation of the particle beam, an irradiation planning device 20 creates an irradiation plan of the particle beam in consideration of the influence of the magnetic field, and applies the particle beam based on this irradiation plan.

Abstract: Provided are an irradiation planning device capable of accurately predicting the RBE of a combined field in a short time and determining an irradiation parameter, an irradiation planning method, and a charged particle irradiation system.

Abstract: A beam irradiation target verification apparatus includes an X-ray switching emission process unit that causes a vertical X-ray emitting unit to emit at least two types of X-rays using an energy-level switching unit, a vertical X-ray detection unit that detects an X-ray emitted from the vertical X-ray emitting unit, a pre-therapy verification image generation process unit, a reference image acquisition unit that acquires a reference image obtained at a therapy planning stage, a comparison process unit. The pre-therapy verification image generation process unit to generate pre-therapy verification images based on detection information of at least two types of X-rays obtained by the vertical X-ray detection unit. The comparison process unit makes comparisons between the pre-therapy verification images and the reference image, and the result output unit outputs a comparison result obtained by the comparison process unit.

Abstract: Provided is an irradiation planning apparatus including: a three-dimensional CT value data acquisition unit (36); a prescription data input processing unit (32) which acquires prescription data; a stopping power ratio conversion unit (37) and a nuclear reaction effective density conversion unit (38) which respectively generate first conversion data (41) and second conversion data (42) on the basis of three-dimensional CT value data; and a calculation unit (33) which calculates a dose distribution on the basis of the prescription data, the first conversion data (41), and the second conversion data (42), wherein the stopping power ratio conversion unit (37) and the nuclear reaction effective density conversion unit (38) perform correction processing for correcting data obtained from the three-dimensional CT value data, using a physical quantity indicative of a likelihood of spalling particles of incident charged particle beam (3), and then determine the dose distribution.

Abstract: Provided is an irradiation planning apparatus including: a three-dimensional CT value data acquisition unit (36); a prescription data input processing unit (32) which acquires prescription data; a stopping power ratio conversion unit (37) and a nuclear reaction effective density conversion unit (38) which respectively generate first conversion data (41) and second conversion data (42) on the basis of three-dimensional CT value data; and a calculation unit (33) which calculates a dose distribution on the basis of the prescription data, the first conversion data (41), and the second conversion data (42), wherein the stopping power ratio conversion unit (37) and the nuclear reaction effective density conversion unit (38) perform correction processing for correcting data obtained from the three-dimensional CT value data, using a physical quantity indicative of a likelihood of spalling particles of incident charged particle beam (3), and then determine the dose distribution.

Abstract: A planning apparatus (70) determines irradiation parameter data (67) for a charged particle irradiation system (1), which radiates charged particles generated by an ion source (2) to a target (80) by accelerating the charged particles by means of a linear accelerator (4) and a synchrotron (5). The planning apparatus is provided with: a planning program (73), which determines the irradiation parameter data (67) with respect to one target (80) by combining charged particles of a plurality of kinds of ion species; and a CPU (71) for executing the planning program. Consequently, the irradiation planning apparatus capable of performing irradiation with desirable dose distribution with respect to the target, the irradiation planning program, an irradiation plan determining method, and the charged particle irradiation system are provided.

Abstract: A beam irradiation target verification apparatus (1) includes an X-ray switching emission process unit (6a) that causes a vertical X-ray emitting unit (13) to emit at least two types of X-rays using an energy-level switching unit (11), a vertical X-ray detection unit (14) that detects an X-ray emitted from the vertical X-ray emitting unit (13), a pre-therapy verification image generation process unit (7) that generates pre-therapy verification images (20B) and (20C) based on detection information on at least two types of X-rays obtained by the vertical X-ray detection unit (14), a reference image acquisition unit (3) that acquires a reference image (20A) obtained at a therapy planning stage, a comparison process unit (8a) that makes comparisons between the pre-therapy verification images (20B) and (20C) and the reference image (20A), and a result output unit (4) that outputs a comparison result obtained by the comparison process unit (8a).

Abstract: A planning apparatus (70) determines irradiation parameter data (67) for a charged particle irradiation system (1), which radiates charged particles generated by an ion source (2) to a target (80) by accelerating the charged particles by means of a linear accelerator (4) and a synchrotron (5). The planning apparatus is provided with: a planning program (73), which determines the irradiation parameter data (67) with respect to one target (80) by combining charged particles of a plurality of kinds of ion species; and a CPU (71) for executing the planning program. Consequently, the irradiation planning apparatus capable of performing irradiation with desirable dose distribution with respect to the target, the irradiation planning program, an irradiation plan determining method, and the charged particle irradiation system are provided.

Abstract: In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.

Abstract: Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission.

Abstract: A particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan while reducing degradation of a particle beam shape, including a particle beam generation portion; a particle beam emission control portion; a two-dimensional beam scanning portion; a sensor portion including first linear electrodes arranged in parallel in a first direction and second linear electrodes arranged in parallel in a second direction orthogonal to the first direction; a beam shape calculation portion that calculates a center of gravity of the particle beam from outputs of each the first linear and second linear electrodes and that obtains a two-dimensional beam shape of the particle beam around the center of gravity; a storage portion that accumulates and stores the two-dimensional beam shapes; and a display portion that displays the two-dimensional beam shapes as a two-dimensional distribution of a dose.

Abstract: A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

Abstract: Provided is a particle beam irradiation apparatus that can measure and display a dose two-dimensional distribution during scan with a simple configuration, while reducing degradation of a particle beam shape.

Abstract: Provided is a particle beam irradiation apparatus capable of highly reliable measurement of a dose of each beam and capable of highly sensitive measurement of a leakage dose caused by momentary beam emission.

Abstract: An imaging device, or a PET device, opposed gamma camera type PET device, or open PET device in particular, that is combined with a radiation therapy device, in which detectors are rotated to reduce incidence of nuclear fragments on the detectors. For example, in an opposed gamma camera type PET device, beam irradiation and detector rotation can be synchronized to prevent the detectors from interfering with the treatment beam and reduce the incidence of nuclear fragments on the detectors. This makes it possible to reduce the incidence of nuclear fragments on the detectors without interfering with a treatment beam, thereby enabling measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or during irradiation.

Abstract: A shielding structure against nuclear fragments (referred to as a shield) is operated according to ON and OFF of beam irradiation so as to reduce incidence of nuclear fragments on detectors during beam irradiation. This enables measurement of annihilation radiations and three-dimensional imaging of the irradiation field immediately after irradiation or even during irradiation.

Abstract: A combined radiation therapy/PET apparatus includes: an open PET device having multi-ring detector rings that are opposed to each other in the direction of the body axis so as to leave a gap therebetween; and a radiation therapy apparatus for performing radiation therapy through the gap. When imaging the condition of an affected area and a treatment beam for monitoring in radiation therapy of irradiating the affected area with X-rays, gamma rays, or particle beams, the apparatus covers a region of interest in the irradiation field of the radiation therapy with the field-of-view of the open PET device, thereby making possible the positioning of the irradiation field and treatment monitoring using PET images.

Abstract: In beam monitoring for detecting annihilation radiations produced by radiation irradiation in radiation therapy for cancer which is performed by irradiating the affected area by X-rays, gamma rays, or particle beams, a detector-shift type combined radiation therapy/PET apparatus is provided with an open PET device that includes a plurality of shiftable multi-ring detector rings; and a radiation irradiation device that is capable of irradiation with a radiation beam through between the detector rings. The apparatus changes the positions of the detector rings, performs irradiation with the radiation beam through between the detector rings, and then performs radiation measurement.