Abstract: Provided is a method that addresses a problem of classifying cells through use of cell autofluorescence, the method including the steps of: acquiring autofluorescence information regarding a plurality of cells through use of an autofluorescence image regarding the plurality of cells; acquiring region information; extracting the autofluorescence information on individual cells from the autofluorescence information regarding the plurality of cells and the region information; and classifying the plurality of cells into two or more groups by performing clustering through use of the autofluorescence information on the individual cells.

Abstract: A reagent contains complex particles, each including a particle and a complex bound to the particle, and an aqueous liquid in which the complex particles are dispersed. The complex includes a Cas protein and a guide RNA bound to the Cas protein.

Abstract: Provided is a nucleic acid detection apparatus including: a distribution unit configured to distribute a sample and a detection reagent to a plurality of individual independent separated compartments, the sample containing a target nucleic acid, and the detection reagent containing an effector protein, crRNA to be bound to the target nucleic acid, and a reporter molecule; an activation unit configured to activate the effector protein through binding of the crRNA to the target nucleic acid; a fluorescence generation unit configured to modify the reporter molecule with the activated effector protein to generate fluorescence; a fluorescence detection unit configured to detect the fluorescence; and an identification unit configured to determine, based on a detection result obtained with the fluorescence detection unit, a fluorescence intensity of each of the individual independent separated compartments, and to identify each of the individual independent separated compartments having a fluorescence intensity exce