Patents by Inventor Takuya Makino

Takuya Makino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8252895
    Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
    Type: Grant
    Filed: July 21, 2010
    Date of Patent: August 28, 2012
    Assignee: Astellas Pharma Inc.
    Inventors: Masahiro Neya, Seiji Yoshimura, Kazunori Kamijyo, Takuya Makino, Minoru Yasuda, Toshio Yamanaka, Eisaku Tsujii, Yukiko Yamagishi
  • Publication number: 20120140414
    Abstract: Provided is a vibrating device which can generate efficient vibrations in a vibrating member and efficiently apply vibrations to a gas, a jet flow generating device in which the vibrating device has been implemented, and an electronic device in which the jet flow generating device has been implemented. A jet flow generating device 10 has a vibrating device 15 including a frame 4, and actuator 5 mounted on the frame 4, and a vibrating member 3 supported on the frame 4 by an elastic supporting member 6. The vibrating member 3 has a side plate 3b formed on the perimeter portion of a disc-shaped vibrating plate 3a, for example. Vibration of the vibrating member 3 applies vibrations to air within chambers 11a and 11b, whereby gas can alternatingly be blown from nozzles 2a and 2b.
    Type: Application
    Filed: February 8, 2012
    Publication date: June 7, 2012
    Applicant: SONY CORPORATION
    Inventors: Hiroichi Ishikawa, Norikazu Nakayama, Takuya Makino, Tomoharu Mukasa, Hiroyuki Ryoson
  • Patent number: 7872097
    Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: January 18, 2011
    Assignee: Astellas Pharma Inc.
    Inventors: Masahiro Neya, Seiji Yoshimura, Kazunori Kamijyo, Takuya Makino, Minoru Yasuda, Toshio Yamanaka, Eisaku Tsujii, Yukiko Yamagishi
  • Publication number: 20100286033
    Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
    Type: Application
    Filed: July 21, 2010
    Publication date: November 11, 2010
    Inventors: Masahiro NEYA, Seiji Yoshimura, Kazunori Kamijyo, Takuya Makino, Minoru Yasuda, Toshio Yamanaka, Eisaku Tsujii, Yukiko Yamagishi
  • Publication number: 20100256048
    Abstract: [Problems] To provide an antibacterial agent, particularly a novel polypeptide compound having an antifungal action. [Means for Solution] As a result of an extensive study on a novel antifungal agent, the inventors have found that an excellent anti-deep-fungal activity is exhibited by introducing a cyclohexylmethylamino group or a piperidylmethylamino group as a partial structure of a natural polypeptide compound, and completed the present invention. The compound of the present invention has an excellent antibacterial activity and is therefore useful as an agent for preventing or treating various fungal infections.
    Type: Application
    Filed: October 28, 2008
    Publication date: October 7, 2010
    Applicant: Astellas Pharma Inc.
    Inventors: Masaki Tomishima, Hiroshi Morikawa, Takuya Makino, Masashi Imanishi, Natsuko Kayakiri, Toru Asano, Takanobu Araki, Toshiya Nakagawa
  • Patent number: 7793709
    Abstract: A jet generating device includes a vibrating member which vibrates gas, a driving unit which drives the vibrating member, and a housing which has a first opening and a first chamber connected to the first opening and containing the gas. The housing supports the vibrating member, and is such that, of sounds generated as a result of vibrating the vibrating member, the sound having a maximum noise level has a predetermined frequency. In addition, the housing discharges the gas as pulsating gas through the first opening as a result of driving the vibrating member.
    Type: Grant
    Filed: April 20, 2006
    Date of Patent: September 14, 2010
    Assignee: Sony Corporation
    Inventors: Tomoharu Mukasa, Kazuhito Hori, Hiroichi Ishikawa, Kanji Yokomizo, Takuya Makino, Norikazu Nakayama
  • Publication number: 20100120672
    Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, a process for preparation thereof, a pharmaceutical composition comprising the same, and a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
    Type: Application
    Filed: April 25, 2008
    Publication date: May 13, 2010
    Inventors: Toshio Yamanaka, Hidenori Ohki, Junya Ishida, Ayako Toda, Yu Harayama, Takuya Makino, Shigeki Kunikawa, Hiroaki Mizuno, Hiroaki Ohtake
  • Publication number: 20090262500
    Abstract: There are provided a cooling device and a heat sink that can effectively radiate heat generated by a heat source while reducing the volume of discharged gas to avoid noise, and an electronic apparatus in which the cooling device and the heat sink are mounted. A heat sink 3 includes cutouts 24a and 24b through which air serving as gas can be taken in from the outside and which are provided on a side where air discharged from first and second nozzles 6 and 7 serving as openings of a jet generating mechanism 2 is received. Therefore, the pressure near the cutouts is decreased by air flow discharged from the first and second nozzles 6 and 7, and outside air is taken in through the cutouts 24a and 24b. Consequently, more gas than gas discharged from the first and second nozzles 6 and 7 is discharged from an outlet of the heat sink. This can minimize the volume of jetted gas to avoid noise, and effectively radiate heat generated by a heat source.
    Type: Application
    Filed: April 4, 2006
    Publication date: October 22, 2009
    Applicant: SONY CORPORATION
    Inventors: Takuya Makino, Hiroshi Takino, Kazuhito Hori, Hiroichi Ishikawa
  • Publication number: 20090170755
    Abstract: The present invention relates to a new cyclic peptide compound or a salt thereof, which has anti-hepatitis C virus activities based on inhibitory activity against the RNA replication of hepatitis C virus replicon, to a process for preparation thereof comprising a rearrangement reaction under a mild acidic condition and the following amino acid changing reactions etc., to a pharmaceutical composition comprising the same, and to a method for prophylactic and/or therapeutic treatment of hepatitis C in a human being or an animal.
    Type: Application
    Filed: October 26, 2006
    Publication date: July 2, 2009
    Inventors: Masahiro Neya, Seiji Yoshimura, Kazunori Kamijyo, Takuya Makino, Minoru Yasuda, Toshio Yamanaka, Eisaku Tsujii, Yukiko Yamagishi
  • Publication number: 20090086416
    Abstract: Provided is a vibrating device which can generate efficient vibrations in a vibrating member and efficiently apply vibrations to a gas, a jet flow generating device in which the vibrating device has been implemented, and an electronic device in which the jet flow generating device has been implemented. A jet flow generating device 10 has a vibrating device 15 including a frame 4, and actuator 5 mounted on the frame 4, and a vibrating member 3 supported on the frame 4 by an elastic supporting member 6. The vibrating member 3 has a side plate 3b formed on the perimeter portion of a disc-shaped vibrating plate 3a, for example. Vibration of the vibrating member 3 applies vibrations to air within chambers 11a and 11b, whereby gas can alternatingly be blown from nozzles 2a and 2b.
    Type: Application
    Filed: February 27, 2006
    Publication date: April 2, 2009
    Applicant: SONY CORPORATION
    Inventors: Hiroichi Ishikawa, Norikazu Nakayama, Takuya Makino, Tomoharu Mukasa, Hiroyuki Ryoson
  • Patent number: 7213338
    Abstract: This invention provides a cooler having an excellent cooling performance, which is capable of being downsized and low-profiled, an electronic apparatus and a method for fabricating the cooler. The cooler (1) comprises lower board member (10) and upper complex board members. The lower board member (10) is made from plastic material and has a cavity portion (11) for allowing water or vapor to be circulated therein. The upper complex board members comprise board member (20) for a condenser part, upper board member (30), and board member (40) for a wick part. The board members (20) and (40) for the condenser part and the wick part, respectively, are made from metallic material having higher thermal conductivity such as copper and nickel. Each of the members has a groove for allowing them to be served as the condenser and the wick.
    Type: Grant
    Filed: May 20, 2005
    Date of Patent: May 8, 2007
    Assignee: Sony Corporation
    Inventors: Minehiro Tonosaki, Naoki Sano, Takuya Makino
  • Patent number: 7199772
    Abstract: An optical switching element having a simple configuration and high response and capable of performing gradation display by area gradation is provided. In a state where a light extracting portion is in contact with an upper substrate, light enters the light extracting portion from the upper substrate, emits from the back face of the light extracting portion, is passed through a lower substrate, and becomes transmission light. In a state where the light extracting portion is attracted by the lower substrate side, the incident light is totally reflected by a total reflection face, and total reflection light emits from a V-shaped groove. The incident light can be switched in two directions and obtained as the transmission light and the total reflection light.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: April 3, 2007
    Assignee: Sony Corporation
    Inventor: Takuya Makino
  • Patent number: 7173748
    Abstract: A micro-mirror for deflecting an incident light is disclosed, wherein the micro-mirror comprises: a mirror section for reflecting an incident light issued from a laser diode; a hinge section including a fixed section and a movable section each having a flat surface; and a drive section having a bi-morph structure made of two or more of materials having different heat expansion coefficient for deflecting said mirror section to change relative angle to said incident light.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: February 6, 2007
    Assignee: Sony Corporation
    Inventors: Masaki Hara, Takuya Makino, Kazuhito Hori, Kazuhiro Hane, Minoru Sasaki
  • Publication number: 20060281398
    Abstract: A jet generator includes a casing containing a gas and having an opening, vibrators attached to the casing, and actuators for actuating the vibrators. The vibrators vibrate with the vibrational forces thereof being synthesized so as to attenuate each other, thereby vibrating the gas to eject a pulsating jet thereof through the opening.
    Type: Application
    Filed: May 1, 2006
    Publication date: December 14, 2006
    Inventors: Kanji Yokomizo, Hiroichi Ishikawa, Takuya Makino, Norikazu Nakayama, Tomoharu Mukasa
  • Publication number: 20060237171
    Abstract: A jet generating device includes a vibrating member which vibrates gas, a driving unit which drives the vibrating member, and a housing which has a first opening and a first chamber connected to the first opening and containing the gas. The housing supports the vibrating member, and is such that, of sounds generated as a result of vibrating the vibrating member, the sound having a maximum noise level has a predetermined frequency. In addition, the housing discharges the gas as pulsating gas through the first opening as a result of driving the vibrating member.
    Type: Application
    Filed: April 20, 2006
    Publication date: October 26, 2006
    Inventors: Tomoharu Mukasa, Kazuhito Hori, Hiroichi Ishikawa, Kanji Yokomizo, Takuya Makino, Norikazu Nakayama
  • Patent number: 7063129
    Abstract: A heat transport device has an evaporator and a condenser connected through a vapor phase channel and a liquid phase channel and has wicks of the condenser arranged symmetrically around an axis orthogonal to the direction of gravity. The flow of fluid in a liquid phase inside the wicks is not disrupted even when the heat transport device is tilted at any angle relative to the horizontal surface or the vertical surface.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: June 20, 2006
    Assignee: Sony Corporation
    Inventors: Takuya Makino, Takashi Mochizuki, Kazuhito Hori, Kazuyoshi Kiga, Noriaki Sakata
  • Patent number: 7061455
    Abstract: An optical switching element having a simple configuration and high response and capable of performing gradation display by area gradation is provided. In a state where a light extracting portion is in contact with an upper substrate, light enters the light extracting portion from the upper substrate, emits from the back face of the light extracting portion, is passed through a lower substrate, and becomes transmission light. In a state where the light extracting portion is attracted by the lower substrate side, the incident light is totally reflected by a total reflection face, and total reflection light emits from a V-shaped groove. The incident light can be switched in two directions and obtained as the transmission light and the total reflection light.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: June 13, 2006
    Assignee: Sony Corporation
    Inventor: Takuya Makino
  • Publication number: 20060098311
    Abstract: A micro-mirror for deflecting an incident light is disclosed, wherein the micro-mirror comprises: a mirror section for reflecting an incident light issued from a laser diode; a hinge section including a fixed section and a movable section each having a flat surface; and a drive section having a bi-morph structure made of two or more of materials having different heat expansion coefficient for deflecting said mirror section to change relative angle to said incident light.
    Type: Application
    Filed: December 8, 2005
    Publication date: May 11, 2006
    Inventors: Masaki Hara, Takuya Makino, Kazuhito Hori, Kazuhiro Hane, Minoru Sasaki
  • Patent number: 7009747
    Abstract: A micro-mirror for deflecting an incident light is disclosed, wherein the micro-mirror comprises: a mirror section for reflecting an incident light issued from a laser diode; a hinge section including a fixed section and a movable section each having a flat surface; and a drive section having a bi-morph structure made of two or more of materials having different heat expansion coefficient for deflecting said mirror section to change relative angle to said incident light.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: March 7, 2006
    Assignee: Sony Corporation
    Inventors: Masaki Hara, Takuya Makino, Kazuhito Hori, Kazuhiro Hane, Minoru Sasaki
  • Patent number: 7000686
    Abstract: A heat transport device includes an evaporator, a condenser, and a vapor channel and a plurality of liquid channels that connect the evaporator and the condenser. The evaporator generates a capillary force to circulate working fluid. This structure prevents the performance deterioration and malfunction due to the entry of vapor-phase working fluid into the liquid channels. Since the cross-sectional areas of the liquid channels gradually decrease from the condenser toward the evaporator, the capillary force at the liquid channels can be increased, and vapor-phase working fluid is prevented from entering the liquid channels. Wicks and the portions of the liquid channels adjacent thereto are filled with liquid-phase working fluid even after dryout occurs, stable operation is achieved.
    Type: Grant
    Filed: January 27, 2005
    Date of Patent: February 21, 2006
    Assignee: Sony Corporation
    Inventors: Takuya Makino, Masaki Hara