Patents by Inventor Tamar Nidam

Tamar Nidam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID STATE FORMS OF VALBENAZINE
    Publication number: 20220127259
    Abstract: Solid state forms of Valbenazine, Valbenazine salts, processes for preparation thereof and pharmaceutical compositions thereof are disclosed. Processes for the preparation of Valbenazine and intermediates in the preparation thereof are further described.
    Type: Application
    Filed: January 5, 2022
    Publication date: April 28, 2022
    Inventors: Ariel Mittelman, Sharona Shachan-Tov, Abed Masarwa, Rotem Sella-Erez, Jonathan Enav, Motti Erlich, Victoria Machtey, Maytal Piran, Marina Yarovoy, Sagit Azran, Einat Kisin-Finfer, Tamar Nidam
  • Solid state forms of valbenazine
    Patent number: 11242341
    Abstract: Solid state forms of Valbenazine, Valbenazine salts, processes for preparation thereof and pharmaceutical compositions thereof are disclosed. Processes for the preparation of Valbenazine and intermediates in the preparation thereof are further described.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: February 8, 2022
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Ariel Mittelman, Sharona Shachan-Tov, Abed Masarwa, Rotem Sella-Erez, Jonathan Enav, Motti Erlich, Victoria Machtey, Maytal Piran, Marina Yarovoy, Sagit Azran, Einat Kisin-Finfer, Tamar Nidam
  • Solid state forms of netarsudil mesylate
    Patent number: 10584100
    Abstract: Disclosed are solid state forms of Netarsudil mesylate, processes for preparation thereof, uses thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: March 10, 2020
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Alexander Mainfeld, Sharona Shachan-tov, Ariel Mittelman, Rotem Sella-Erez, Yifat Ronen, Tamar Nidam
  • SOLID STATE FORMS OF VALBENAZINE
    Publication number: 20200048244
    Abstract: Solid state forms of Valbenazine, Valbenazine salts, processes for preparation thereof and pharmaceutical compositions thereof are disclosed. Processes for the preparation of Valbenazine and intermediates in the preparation thereof are further described.
    Type: Application
    Filed: October 6, 2017
    Publication date: February 13, 2020
    Inventors: Ariel Mittelman, Sharona Shachan-Tov, Abed Masarwa, Rotem Sella-Erez, Jonathan Enav, Motti Erlich, Victoria Machtey, Maytal Piran, Marina Yarovoy, Sagit Azran, Einat Kisin-Finfer, Tamar Nidam
  • SOLID STATE FORMS OF NETARSUDIL MESYLATE
    Publication number: 20190389807
    Abstract: Disclosed are solid state forms of Netarsudil mesylate, processes for preparation thereof, uses thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: September 4, 2019
    Publication date: December 26, 2019
    Inventors: Alexander Mainfeld, Sharona Shachan-tov, Ariel Mittelman, Rotem Sella-Erez, Yifat Ronen, Tamar Nidam
  • Solid state forms of netarsudil mesylate
    Patent number: 10442770
    Abstract: Disclosed are solid state forms of Netarsudil mesylate, processes for preparation thereof, uses thereof, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: October 15, 2019
    Assignee: ASSIA CHEMICAL INDUSTRIES LTD.
    Inventors: Alexander Mainfeld, Sharona Shachan-tov, Ariel Mittelman, Rotem Sella-Erez, Yifat Ronen, Tamar Nidam
  • SOLID STATE FORMS OF NETARSUDIL MESYLATE
    Publication number: 20180215715
    Abstract: Disclosed are solid state forms of Netarsudil mesylate, processes for preparation thereof, uses thereof, and pharmaceutical compositions thereof.
    Type: Application
    Filed: February 1, 2018
    Publication date: August 2, 2018
    Inventors: Alexander Mainfeld, Sharona Shachan-tov, Ariel Mittelman, Rotem Sella-Erez, Yifat Ronen, Tamar Nidam
  • Processes for the preparation and purification of gabapentin enacarbil
    Patent number: 8283487
    Abstract: Gabapentin enacarbil was prepared and purified from intermediates such as 1-haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a C1 to C10 alcohol or C1 to C10 primary amine, a solvent selected from the group consisting of: acetonitrile, C3 to C7 ketone, C5 to C10 ether, C2 to C7 ester, C5 to C10 hydrocarbon and a combination thereof; a 1-haloalkyl haloformate of the following formula: wherein each X is independently selected from Br, I, or Cl; R1 is alkyl or H; and a C6 to C21 tertiary amine.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: October 9, 2012
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Elena Ben Moha-Lerman, Tamar Nidam, Meital Cohen, Sharon Avhar-Maydan, Anna Balanov
  • Crystal forms of O-desmethylvenlafaxine fumarate
    Patent number: 8063250
    Abstract: Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical compositions thereof.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: November 22, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Valerie Niddam-Hildesheim, Eli Lancry, Sharona Shachan-tov, Sigalit Levi, Tamar Nidam
  • SOLID STATES OF O-DESMETHYLVENLAFAXINE SALTS
    Publication number: 20110112200
    Abstract: The present invention provides crystalline and amorphous salts of O-desmethylvenlafaxine and processes for preparing said salts of O-desmethylvenlafaxine. The present invention further provides pharmaceutical compositions comprising said salts of O-desmethylvenlafaxine.
    Type: Application
    Filed: June 16, 2009
    Publication date: May 12, 2011
    Inventors: Valerie Niddam-Hildesheim, Tamar Nidam, Eli Lancry
  • Purification of rosuvatatin intermediate by thin film evaporation and chemical method
    Patent number: 7884226
    Abstract: Provided are processes for the purification of a pure rosuvastatin intermediate by thin film evaporation and chemical method, and conversion of the intermediate to rosuvastatin or salts thereof.
    Type: Grant
    Filed: July 14, 2008
    Date of Patent: February 8, 2011
    Assignee: Teva Pharmaceutical Industries, Ltd.
    Inventors: Tamar Nidam, Omer Malachi, Irena Veinberg, Valerie Niddam-Hildesheim, Vinod Kumar Kansal, Harish Ranjan, Appu Ekambaram Ponnuswamy, Sunil Rokad, Surat Kiran, Debashish Das
  • PROCESSES FOR THE PREPARATION AND PURIFICATION OF GABAPENTIN ENACARBIL
    Publication number: 20100160665
    Abstract: Gabapentin enacarbil was prepared and purified from intermediates such as 1-haloalkyl carbamate or carbonate and diacid acetal skeleton. For example, a 1-haloalkyl carbonate or carbamate was prepared by combining a C1 to C10 alcohol or C1 to C10 primary amine, a solvent selected from the group consisting of: acetonitrile, C3 to C7 ketone, C5 to C10 ether, C2 to C7 ester, C5 to C10 hydrocarbon and a combination thereof; a 1-haloalkyl haloformate of the following formula: wherein each X is independently selected from Br, I, or Cl; R1 is alkyl or H; and a C6 to C21 tertiary amine.
    Type: Application
    Filed: November 26, 2009
    Publication date: June 24, 2010
    Applicant: TEVA PHARMACEUTICAL INDUSTRIES LTD.
    Inventors: Elena Ben Moha-Lerman, Tamar Nidam, Meital Cohen, Sharon Avhar-Maydan, Anna Balanov
  • Processes for preparation of ziprasidone
    Patent number: 7667037
    Abstract: Provided are processes for preparing ziprasidone from CEI and BIPT.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: February 23, 2010
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Gideon Pilarsky, Natalia Shenkar, Marioara Mendelovici, Tamar Nidam, Anna Balanov
  • Method for the purification of lansoprazole
    Patent number: 7622588
    Abstract: The present invention provides a method for preparing a substantially pure lansoprazole containing less than about 0.2% (wt/wt) impurities including sulfone/sulfide derivatives. The present invention also provides a process for recrystallizing lansoprazole to obtain a lansoprazole containing less than about 0.1% (wt/wt) water.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: November 24, 2009
    Assignee: Teva Pharmaceutical Industries Ltd.
    Inventors: Claude Singer, Anita Liberman, Irena Veinberg, Nina Finkelstein, Tamar Nidam
  • Processes for the preparation of odesmethylvenlafaxine, free from its dimer impurities
    Publication number: 20090234020
    Abstract: The present invention provides isolated O-desmethylvenlafaxine impurities ODV-Dimer and ODV-N-Dimer, their use as a reference marker and reference standard, and a process for the preparation of O-desmethylvenlafaxine free from said impurities
    Type: Application
    Filed: March 6, 2009
    Publication date: September 17, 2009
    Inventors: Valarie Niddam-Hildesheim, Tamar Nidam, Yuri Vollerner, Miri Adler, Miri Kravitz, Sharona Shachan-tov
  • Crystal forms of O-desmethylvenlafaxine fumarate
    Publication number: 20090170948
    Abstract: Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical compositions thereof.
    Type: Application
    Filed: November 26, 2008
    Publication date: July 2, 2009
    Inventors: Valerie Niddam-Hildesheim, Eli Lancry, Sharona Shachan-tov, Sigalit Levi, Tamar Nidam
  • Processes for the synthesis of O-Desmethylvenlafaxine
    Publication number: 20090137846
    Abstract: The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
    Type: Application
    Filed: October 20, 2008
    Publication date: May 28, 2009
    Inventors: Valerie Niddam-Hildesheim, Tamar Nidam, Ben-Zion Dolitzky, Gustavo Frenkel
  • Purification of rosuvatatin intermediate by thin film evaporation and chemical method
    Publication number: 20090099383
    Abstract: Provided are processes for the purification of a pure rosuvastatin intermediate by thin film evaporation and chemical method, and conversion of the intermediate to rosuvastatin or salts thereof.
    Type: Application
    Filed: July 14, 2008
    Publication date: April 16, 2009
    Inventors: Tamar Nidam, Omer Malachi, Irena Veinberg, Valerie Niddam-Hildesheim, Vinod Kumar Kansal, Harish Ranjan, Appu Ekambaram Ponnuswamy, Sunil Rokad, Surat Kiran, Debashish Das
  • Processes for the synthesis of O-desmethylvenlafaxine
    Publication number: 20090069601
    Abstract: The present invention describes processes for the preparation of O-desmethylvenlafaxine and tridesmethylvenlafaxine, which may be used as an intermediate in preparing O-desmethylvenlafaxine.
    Type: Application
    Filed: December 6, 2007
    Publication date: March 12, 2009
    Inventors: Valerie Niddam-Hildesheim, Tamar Nidam, Ben-Zion Dolitzky
  • Processes for the synthesis of O-desmethylvenlafaxine
    Publication number: 20090062572
    Abstract: The present invention describes processes for the preparation of O-desmethylvenlafaxine and the intermediates cyclohexylbenzylcyanide and tridesmethylvenlafaxine, which may be used as intermediates in preparing O-desmethylvenlafaxine.
    Type: Application
    Filed: July 26, 2007
    Publication date: March 5, 2009
    Inventors: Valerie Niddam-Hildesheim, Natalia Shenkar, Tamar Nidam