Abstract: A treatment application garment, such as a glove or a sock, is disclosed. The garment allows for various treatments directed toward the fingers and toes, such as the fingernails and toenails. For example, each digit of the garment may contain a pocket filled with acetone and an absorbent pad placed adjacent the pocket. The hand or foot is inserted into the garment such that the nail is positioned below the absorbent pad. The pocket is ruptured, allowing the acetone to be absorbed by the absorbent pad and constantly applied to the nail to remove polish therefrom. After the treatment is complete, the glove may be removed and the open end thereof tied off, thereby containing the acetone and the smell thereof within the glove. Other features and treatments are also disclosed.