Patents by Inventor Tandri Harikrishna

Tandri Harikrishna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11896521
    Abstract: The present invention provides improved devices for removing energy and fluid from body fluid containing spaces and surfaces of a mammal, and new uses for such devices, including fluid removal, energy removal, increasing metabolic rate; promoting weight loss; preventing esophageal burn-through, reducing beta-amylase accumulation in the brain, delaying or inhibiting the onset of Alzheimer's and other senile dementia.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: February 13, 2024
    Assignee: CoolTech, LLC
    Inventors: Brian Lipford, Tandri Harikrishna, Ben Lane, Aaron Pearl
  • Patent number: 11523937
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The method and device provide for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest. Similarly, excess fluid removal may be achieved for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function.
    Type: Grant
    Filed: June 16, 2020
    Date of Patent: December 13, 2022
    Assignee: The Johns Hopkins Unviversity
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Publication number: 20210128347
    Abstract: The present invention provides improved devices for removing energy and fluid from body fluid containing spaces and surfaces of a mammal, and new uses for such devices, including fluid removal, energy removal, increasing metabolic rate; promoting weight loss; preventing esophageal burn-through, reducing beta-amylase accumulation in the brain, delaying or inhibiting the onset of Alzheimer's and other senile dementia.
    Type: Application
    Filed: July 13, 2020
    Publication date: May 6, 2021
    Inventors: Brian Lipford, Tandri Harikrishna, Ben Lane, Aaron Pearl
  • Publication number: 20210128346
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The method and device provide for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest Similarly, excess fluid removal may be achieved for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function.
    Type: Application
    Filed: June 16, 2020
    Publication date: May 6, 2021
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Publication number: 20180153737
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The method and device provide for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest. Similarly, excess fluid removal may be achieved for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function.
    Type: Application
    Filed: July 18, 2017
    Publication date: June 7, 2018
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Patent number: 9744071
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling, fluid removal and/or energy removal. The present invention provides for removal of fluid and cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of mucus to the dry fluid yields evaporation of body fluid, removal of energy, cooling of the anatomical feature, and systemic cooling. Therefore, therapeutic hypothermia may be achieved for neuroprotection of various organs after ischemic insult, like the brain after cardiac arrest. Similarly, excess fluid removal is achievable for treatment of cardiogenic shock or other conditions that cause significant fluid build-up, especially in cases of compromised renal function.
    Type: Grant
    Filed: January 28, 2013
    Date of Patent: August 29, 2017
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Patent number: 9629745
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling. The method and device provide for cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation and cooling of the anatomical feature and/or systemic cooling, as intended. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: April 25, 2017
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Publication number: 20150250646
    Abstract: The present invention provides improved devices for removing energy and fluid from body fluid containing spaces and surfaces of a mammal, and new uses for such devices, including fluid removal, energy removal, increasing metabolic rate; promoting weight loss; preventing esophageal burn-through, reducing beta-amylase accumulation in the brain, delaying or inhibiting the onset of Alzheimer's and other senile dementia.
    Type: Application
    Filed: December 19, 2014
    Publication date: September 10, 2015
    Inventors: Brian Lipford, Tandri Harikrishna, Ben Lane, Aaron Pearl
  • Patent number: 8932339
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling. The method and device provide for cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation and cooling of the anatomical feature and/or systemic cooling, as intended. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest.
    Type: Grant
    Filed: October 29, 2013
    Date of Patent: January 13, 2015
    Assignee: The Johns Hopkins University
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Publication number: 20140053834
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling. The method and device provide for cooling of various bodily fluid-containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation and cooling of the anatomical feature and/or systemic cooling, as intended. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest.
    Type: Application
    Filed: October 29, 2013
    Publication date: February 27, 2014
    Applicant: The Johns Hopkins University
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman
  • Publication number: 20130103126
    Abstract: The present invention provides a method and device for non-invasive anatomical and systemic cooling. The method and device provide for cooling of various bodily fluid- containing spaces or surfaces, such as mucus-containing spaces or surfaces via delivery of a dry fluid not including a coolant into or upon the mucus-containing space or surface. Exposure of such mucus to the dry fluid results in evaporation and cooling of the anatomical feature and/or systemic cooling, as intended. In this fashion, therapeutic hypothermia may be achieved to provide for neuroprotection of various organs after ischemic insult, such the brain after cardiac arrest.
    Type: Application
    Filed: February 16, 2011
    Publication date: April 25, 2013
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Tandri Harikrishna, Menekhem Muz Zviman