Abstract: An extracorporeal pumping method includes receiving an inlet fluid into a compressible-expandable bladder sealably mounted within a housing and moving an actuating member mounted within a fluid chamber of a hydraulic actuating sub-assembly. A pressure transmissive fluid is displaced from the fluid chamber into the housing. The method includes compressing a volume of the bladder in the housing using the transmissive fluid displaced into the housing, the compressed bladder ejecting the inlet fluid from the bladder to provide an outlet fluid under pulsatile pressure. The actuating member is moved within the fluid chamber and the displaced transmissive fluid is returned from the housing into the fluid chamber. The method includes expanding the compressed bladder in the housing and receiving additional inlet fluid into the bladder. The movement of the actuating member is controlled such that the outlet fluid exhibits a predetermined pulse rate, stroke volume, and upstroke rise time.

Abstract: A pulsatile blood circulating pump system for use in cardiopulmonary bypass, ventricular assist (LVAD, RVAD, BiVAD), ECMO, organ preservation, fetal cardiac bypass, cancer treatment, and areas of circulation research, which is controlled to produce blood flow that approximates physiological blood flow. The pump system includes a pulsating mechanism having a housing defining a chamber with a compressible-expandable bladder sealably mounted. A hydraulic actuator having a pressure imparting member that acts upon pressure transmissive fluid contained within the actuator chamber to generate a pulsatile pressure on the transmissive fluid, which results in pulsatile pressure being exerted on bladder to controllably vary the volume thereof. Additionally, the system includes a compact, motor that is associated with the hydraulic actuator for moving the pressure imparting member within the fluid chamber and further includes a fully programmable motion controller that controls the motor.

Abstract: An extracorporeal pumping method includes receiving an inlet fluid into a compressible-expandable bladder sealably mounted within a housing and moving an actuating member mounted within a fluid chamber of a hydraulic actuating sub-assembly. A pressure transmissive fluid is displaced from the fluid chamber into the housing. The method includes compressing a volume of the bladder in the housing the transmissive fluid displaced into the housing, the compressed bladder ejecting the inlet fluid from the bladder to provide an outlet fluid under pulsatile pressure. The actuating member is moved within the fluid chamber and the displaced transmissive fluid is returned from the housing into the fluid chamber. The method includes expanding the compressed bladder in the housing and receiving additional inlet fluid into the bladder. The movement of the actuating member is controlled such that the outlet fluid exhibits a predetermined pulse rate, stroke volume, and upstroke rise time.

Abstract: A pulsatile blood circulating pump system that is adapted for use in cardiopulmonary bypass, ventricular assist (LVAD, RVAD, BiVAD), ECMO, organ preservation, fetal cardiac bypass, cancer treatment, and various areas of circulation research, which can be controlled in such a way as to produce a desired blood flow that closely approximates the physiological blood flow of the patient. The pump system includes a pulsating mechanism having a housing defining a chamber within which a compressible-expandable bladder is sealably mounted. The system further includes a hydraulic actuator having a pressure imparting member that acts upon a pressure transmissive fluid contained within the actuator chamber in a manner to generate a pulsatile pressure on the transmissive fluid, which, in turn, results in a pulsatile pressure being exerted on bladder in a manner to controllably vary the volume thereof.

Abstract: A pulsatile blood circulating pump system that is adapted for use in cardiopulmonary bypass, ventricular assist (LVAD, RVAD, BiVAD), ECMO, organ preservation, fetal cardiac bypass, cancer treatment, and various areas of circulation research, which can be controlled in such a way as to produce a desired blood flow that closely approximates the physiological blood flow of the patient. The pump system includes a pulsating mechanism having a housing defining a chamber within which a compressible-expandable bladder is sealably mounted. The system further includes a hydraulic actuator having a pressure imparting member that acts upon a pressure transmissive fluid contained within the actuator chamber in a manner to generate a pulsatile pressure on the transmissive fluid, which, in turn, results in a pulsatile pressure being exerted on bladder in a manner to controllably vary the volume thereof.

Abstract: A pulsatile blood circulating pump system that is adapted for use in cardiopulmonary bypass, ventricular assist (LVAD, RVAD, BiVAD), ECMO, organ preservation, fetal cardiac bypass, cancer treatment, and various areas of circulation research, which can be controlled in such a way as to produce a desired blood flow that closely approximates the physiological blood flow of the patient. The pump system includes a pulsating mechanism having a housing defining a chamber within which a compressible-expandable bladder is sealably mounted. The system further includes a hydraulic actuator having a pressure imparting member that acts upon a pressure transmissive fluid contained within the actuator chamber in a manner to generate a pulsatile pressure on the transmissive fluid, which, in turn, results in a pulsatile pressure being exerted on bladder in a manner to controllably vary the volume thereof.