Abstract: A system and method that can simultaneously acquire electrocardiogram or pulse rate data (42, 44, 46), dynamically perform time-frequency (70) and chaotic analysis (60) in real-time, visually display the results in a convenient graphical format (50) and store the results in a computer file format (50).

Abstract: A system and method that can simultaneously acquire electrocardiogram or pulse rate data (42, 44, 46), dynamically perform time-frequency (70) and chaotic analysis (60) in real-time, visually display the results in a convenient graphical format (50) and store the results in a computer file format (50).

Abstract: The present invention relates to a method and system that enables continuous real-time analysis of both ciliary beat frequency and metachronal wave frequency from a single spot in excised native ciliated epithelial tissues as well as in primary and subsequent epithelial cultures. Such method and system utilizes the concept of time-scale wavelet analysis and Hilbert Transformation for backscattered light derived from a confocal (conjugate) spot on the moving cilia. This light contains inherent high and low frequency components corresponding to CBF and MWF.

Abstract: The present invention relates to a novel antifungal antibacterial compound 2-methylheptylisonicotinate of formula 1 below obtained from natural sources and to a process for the isolation thereof.

Abstract: A method of measuring nonstationary oscillatory motion of a sample is disclosed. The method comprisesing the steps of illuminating a sample with an illuminating optical fiber; detecting reflectedbackscattered light from the sample with a plurality of detecting optical fibers; coupling each optical fiber of the plurality of detecting optical fibers with a modulating optical fiber; and generating measurements of the nonstationary oscillatory motion of the sample. An apparatus for measuring nonstationary oscillatory motion of a sample is also disclosed. The apparatus comprises a light source; an illuminating optical fiber coupled to the light source; and a plurality of optical fibers positioned around the illuminating optical fiber and coupled to receive reflectedbackscattered light from the sample.

Abstract: A method of measuring oscillatory motion of a sample is disclosed. The method comprises the steps of illuminating a sample with an illuminating optical fiber; detecting backscattered light from the sample with a plurality of detecting optical fibers; coupling each optical fiber of the plurality of detecting optical fibers with a modulating optical fiber; and generating measurements of the oscillatory motion of the sample. An apparatus for measuring oscillatory motion of a sample is also disclosed. The apparatus comprises a light source; an illuminating optical fiber coupled to the light source; and a plurality of optical fibers positioned around the illuminating optical fiber and coupled to receive backscattered light from the sample.

Abstract: An apparatus is disclosed for screening a compound by monitoring its interactions with a specimen having fluorophore loaded target cells. The apparatus comprises an optical illumination unit comprising a light source wherein light from the light source is directed to illuminate the specimen; a fluorescence discrimination unit which is coupled to receive emitted light from the specimen and separate at least three emitted wavelengths of light from said emitted light; and a fluorescence detection unit which is coupled to the fluorescence discrimination unit counts photons emitted by the wavelengths of emitted light. A method of screening a compound by monitoring its interactions with a specimen having fluorophore loaded target cells is also described. The method comprises the steps of coupling a light source to the specimen to illuminate the specimen; separating at least three wavelengths of light emitted by the specimen, and detecting photon counts from the three emitted wavelengths of light.

Abstract: The present invention relates to a novel antifungal antibacterial compound 2-methylheptylisonicotinate of formula 1 below obtained from natural sources and to a process for the isolation thereof.

Abstract: Embodiments of the invention provide methods of preparing an activated acridinium microparticle. Generally, the methods involve direct covalent coupling or an affinity format. The direct covalent coupling method involves coating a microparticle with a proteinaceous compound. Then, a 10-methyl-N-tosyl-N-(2-carboxyethyl)-9-acridinium carboximide trifluoromethane sulfonate is coupled to the proteinaceous compound. In the affinity format, a microparticle is coated with a biotinylated proteinaceous compound. The microparticle is reacted with an anti-biotin labelled 10-methyl-N-tosyl-N-(2-carboxyethyl)-9-acridinium carboximide trifluoromethane sulfonate. Methods are also provided for using such a microparticle. Those methods of use can estimate transfer efficiency, calibrate optics, and measure membrane pore size of a chemiluminescence based instrument. Test elements for analytical instruments are also provided.