Abstract: The invention provides a process of purification of antibody or fusion protein from protein mixture comprising product and process related impurities. The process provides the use of hydroxyapatite chromatography for the separation of low molecular weight impurities and basic variants. In addition, invention further provides a scalable purification process to remove product and process related impurities.

Abstract: The present invention relates to novel liquid formulations comprising pharmacologically active fusion protein. The present invention discloses the use of histidine buffer in combination with other excipients to stabilize the fusion protein by lowering the product related impurities. In another aspects invention provides a formulation of fusion protein with low viscosity.

Abstract: A device may receive event data identifying events associated with user devices utilizing a video conferencing system, and may utilize the event data to train one or more fraud detection models. The device may receive, from a user device, user traffic including at least one of API traffic or media traffic, and may identify characteristics of the user traffic, such as activity related features, application-specific features, and dial-in number-specific features. The device may process at least one of the activity related features, the application-specific features, or the dial-in number-specific features, with the one or more fraud detection models, to determine whether the user traffic from the user device is anomalous or normal, and may block at least one of an IP address of the user device, a telephone number of the user device, or a meeting of the user device, based on determining that the user traffic is anomalous.

Abstract: A solid-state thermal battery system is disclosed herein. The system includes a stationary thermal storage medium that can be charged by adding heat to the thermal storage medium. Actuated heat engines can be utilized to discharge the solid-state thermal battery, converting the heat stored in the thermal storage medium into electricity. The heat engines are actuated in a manner that reduces thermal gradients in the thermal storage medium to increase the efficiency of the system. In one embodiment, the thermal storage medium is contained in a main chamber of an insulated container. The heat engines are stored, when idle, in an ancillary chamber adjacent to the main chamber and moved into the main chamber by an actuation system to begin discharging the solid-state thermal battery. The heat engines follow a path during discharge to dynamically move between regions of the thermal storage medium to reduce thermal gradients induced therein.

Abstract: A solid-state thermal battery system is disclosed herein. The system includes a stationary thermal storage medium that can be charged by adding heat to the thermal storage medium. Actuated heat engines can be utilized to discharge the solid-state thermal battery, converting the heat stored in the thermal storage medium into electricity. The heat engines are actuated in a manner that reduces thermal gradients in the thermal storage medium to increase the efficiency of the system. In one embodiment, the thermal storage medium is contained in a main chamber of an insulated container. The heat engines are stored, when idle, in an ancillary chamber adjacent to the main chamber and moved into the main chamber by an actuation system to begin discharging the solid-state thermal battery. The heat engines follow a path during discharge to dynamically move between regions of the thermal storage medium to reduce thermal gradients induced therein.

Abstract: A solid-state thermal battery system is disclosed herein. The system includes a stationary thermal storage medium that can be charged by adding heat to the thermal storage medium. Actuated heat engines can be utilized to discharge the solid-state thermal battery, converting the heat stored in the thermal storage medium into electricity. The heat engines are actuated in a manner that reduces thermal gradients in the thermal storage medium to increase the efficiency of the system. In one embodiment, the thermal storage medium is contained in a main chamber of an insulated container. The heat engines are stored, when idle, in an ancillary chamber adjacent to the main chamber and moved into the main chamber by an actuation system to begin discharging the solid-state thermal battery. The heat engines follow a path during discharge to dynamically move between regions of the thermal storage medium to reduce thermal gradients induced therein.

Abstract: Enhanced Coulomb repulsion screening around light element nuclei is achieved by way of utilizing electromagnetic (EM) radiation to induce plasmon oscillations in target structures (e.g., nanoparticles) in a way that produces high density electron clouds in localized regions of the target structures, thereby generating charge density variations around light element atoms located in the localized regions. Each target structure includes an electrically conductive body including light elements (e.g., a metal hydride/deuteride/tritide) that is configured to undergo plasmon oscillations in response to the applied EM radiation. The induced oscillations causes free electrons to converge in the localized region, thereby producing transient high electron charge density levels that enhance Coulomb repulsion screening around light element (e.g., deuterium) atoms located in the localized regions.

Abstract: Enhanced Coulomb repulsion (electron) screening around light element nuclei is achieved by way of utilizing target structures (e.g., nanoparticles) that undergo plasmon oscillation when subjected to electromagnetic (EM) radiation, whereby transient high density electron clouds are produced in localized regions of the target structures during each plasmon oscillation cycle. Each target structure includes an integral body composed of an electrically conductive material that contains light element atoms (e.g., metal hydrides, metal deuterides or metal tritides). The integral body is also configured (i.e., shaped/sized) to undergo plasmon oscillations in response to the applied EM radiation such that the transient high density electron clouds are formed during each plasmon oscillation cycle, whereby brief but significantly elevated charge density variations are generated around light element (e.g.

Abstract: Enhanced Coulomb repulsion (electron) screening around light element nuclei is achieved by way of utilizing target structures (e.g., nanoparticles) that undergo plasmon oscillation when subjected to electromagnetic (EM) radiation, whereby transient high density electron clouds are produced in localized regions of the target structures during each plasmon oscillation cycle. Each target structure includes an integral body composed of an electrically conductive material that contains light element atoms (e.g., metal hydrides, metal deuterides or metal tritides). The integral body is also configured (i.e., shaped/sized) to undergo plasmon oscillations in response to the applied EM radiation such that the transient high density electron clouds are formed during each plasmon oscillation cycle, whereby brief but significantly elevated charge density variations are generated around light element (e.g.

Abstract: Enhanced Coulomb repulsion screening around light element nuclei is achieved by way of utilizing electromagnetic (EM) radiation to induce plasmon oscillations in target structures (e.g., nanoparticles) in a way that produces high density electron clouds in localized regions of the target structures, thereby generating charge density variations around light element atoms located in the localized regions. Each target structure includes an electrically conductive body including light elements (e.g., a metal hydride/deuteride/tritide) that is configured to undergo plasmon oscillations in response to the applied EM radiation. The induced oscillations causes free electrons to converge in the localized region, thereby producing transient high electron charge density levels that enhance Coulomb repulsion screening around light element (e.g., deuterium) atoms located in the localized regions.