Patents by Inventor Tasuku Hirayama

Tasuku Hirayama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Iron (II) ion detection agent and detection method using same
    Patent number: 10451640
    Abstract: An Fe(II) ion detection agent, and related method, capable of fluorescently detecting Fe(II) ions quickly with high sensitivity is disclosed. The Fe(II) ion detection agent can be a compound represented by formula (I) (fluorescence probe): wherein R1 and R2 represent lower alkyl; R3 and R4 represent hydrogen; R5 represents hydrogen, hydroxyl, or a group represented by formula (A): —NR51R52 wherein R51 and R52 represent lower alkyl; R6 and R7 represent hydrogen; ring A represents an aromatic ring; V represents O or SiR10R11 wherein R10 and R11 are the same or different and represent, hydrogen or lower alkyl; W represents CH2, CO; Z represents O; m and n are the same or different and represent 0 or 1. The agent can be combined with a compound having at least three coordinating positions.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: October 22, 2019
    Assignee: Cellspect Co., Ltd.
    Inventors: Hideko Nagasawa, Tasuku Hirayama
  • IRON (II) ION DETECTION AGENT AND DETECTION METHOD USING THE SAME
    Publication number: 20160356796
    Abstract: An Fe(II) ion detection agent, and related method, capable of fluorescently detecting Fe(II) ions quickly with high sensitivity is disclosed. The Fe(II) ion detection agent can be a compound represented by formula (I) (fluorescence probe): wherein R1 and R2 represent lower alkyl; R3 and R4 represent hydrogen; R5 represents hydrogen, hydroxyl, or a group represented by formula (A): —NR51R52 wherein R51 and R52 represent lower alkyl; R6 and R7 represent hydrogen; ring A represents an aromatic ring; V represents O or SiR10R11 wherein R10 and R11 are the same or different and represent, hydrogen or lower alkyl; W represents CH2, CO; Z represents O; m and n are the same or different and represent 0 or 1. The agent can be combined with a compound having at least three coordinating positions.
    Type: Application
    Filed: January 16, 2015
    Publication date: December 8, 2016
    Applicant: Metallogenics Co., Ltd.
    Inventors: Hideko NAGASAWA, Tasuku HIRAYAMA
  • Fluorescent probes for detection of copper
    Patent number: 8865914
    Abstract: The invention provides fluorescent sensors for the selective detection of a metal such as copper. The sensors may be considered to be derivatives of cyanine, fluorescein, rhodamine, rhodol, Tokyo green, or BODIPY. The sensors find particular use in detecting copper in cells and living animals.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: October 21, 2014
    Assignee: The Regents of the University of California
    Inventors: Christopher J. Chang, Genevieve C. Van De Bittner, Tasuku Hirayama, Jefferson Chan