Abstract: A clip device for gripping biological tissue of a patient includes a clip having a first arm and second arm closeable by operation of a wire that is reciprocally moveable in a longitudinal channel of a sheath; and a bendable member at a distal end region of the sheath. The bendable member can be an integral portion of the sheath or a separate structure. The bendable member is configured to allow a distal end of a clip to rotate or swing toward a proximal end region of the sheath of the device, which orients the clip relative to the sheath to facilitate grasping of tissue even when the approach of the clip is tangential to the tissue, e.g., at an angle (?) less than 90. The bendable member can be configured to allow a distal end of a clip to rotate or swing toward a proximal end region of a sheath and form an angle of up to at least about 45 degrees, such up to about 60 degrees or up to about 90 degrees, or higher.

Abstract: A clip device for gripping biological tissue of a patient includes a clip having a first arm and second arm closeable by operation of a wire that is reciprocally moveable in a longitudinal channel of a sheath; and a bendable member at a distal end region of the sheath. The bendable member can be an integral portion of the sheath or a separate structure. The bendable member is configured to allow a distal end of a clip to rotate or swing toward a proximal end region of the sheath of the device, which orients the clip relative to the sheath to facilitate grasping of tissue even when the approach of the clip is tangential to the tissue, e.g., at an angle (?) less than 90. The bendable member can be configured to allow a distal end of a clip to rotate or swing toward a proximal end region of a sheath and form an angle of up to at least about 45 degrees, such up to about 60 degrees or up to about 90 degrees, or higher.

Abstract: A clip indwelling device includes an insertion portion; a power transmission member; a hollow member in which an insertion passage is formed; an arm member which includes a first and a second arms inserted into the insertion passage to protrude from a distal end of the hollow member, is connected to the power transmission member, and is constituted to switch between an open state and a closed state due to advance-retract movement of the power transmission member, and an adjustment mechanism which disposes the first and the second arms such that protrusion lengths of the first and the second arms in an axial direction with respect to the hollow member become equivalent to each other in the open state and disposes the first and the second arms such that the protrusion lengths thereof in the axial direction with respect to the hollow member differ from each other in the closed state.

Abstract: Treatment device with clip is reciprocally closed and opened in one operation and locked in a second, distinct operation. The clip has a first arm and second arm which are configured to move in a direction toward and away from each other to close and open the clip; a wire connected to a proximal end of the clip configured to reciprocally move within a sheath to close and open the clip; and one or more latch elements on the clip configured to lock the clip in a closed state. Operating the wire does not lock the clip in a closed state in a single operation. Rather, the clip can be locked by another operation that is distinct from operating the wire for reciprocal movement, such as operating a stopper, an inner sheath reciprocally movable to slid over the clip arms, or a locking ring slidable over the clip arms.

Abstract: A clip for gripping tissue can having a first arm with a first claw at a distal end of the first arm, and second arm, with a second claw at a distal end of the second arm, in which the first arm and second arm are configured to move in a direction toward each other to close the clip. The clips include one or more anchors on the arms of the clip which protrude in a direction other than the direction that the first arm and second arm are configured to move toward each other to close the clip. Such anchors can more readily attach to tissue of a patient upon contact than clips without an anchor.

Abstract: A clip device for gripping biological tissue of a patient includes a clip having a first arm and second arm closeable by operation of a wire that is reciprocally moveable in a longitudinal channel of a sheath; and a bendable member at a distal end region of the sheath. The bendable member can be an integral portion of the sheath or a separate structure. The bendable member is configured to allow a distal end of a clip to rotate or swing toward a proximal end region of the sheath of the device, which orients the clip relative to the sheath to facilitate grasping of tissue even when the approach of the clip is tangential to the tissue, e.g., at an angle (?) less than 90. The bendable member can be configured to allow a distal end of a clip to rotate or swing toward a proximal end region of a sheath and form an angle of up to at least about 45 degrees, such up to about 60 degrees or up to about 90 degrees, or higher.