Patents by Inventor Ted Pham

Ted Pham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mitochondrial apoptotic sensor
    Patent number: 10718756
    Abstract: Mitochondria are central to the intrinsic apoptotic pathway of programmed cell death. Commitment to cell death occurs upon mitochondrial outer membrane permeabilization, and dysregulation of this vital apoptotic control point is implicated in various pathologies. Provided herein are novel sensors which can detect, in real time and with great sensitivity, the release of protons from intact mitochondria caused by mitochondrial outer membrane permeabilization. Embodiments include graphene based ion-sensitive field effect transistors.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: July 21, 2020
    Assignee: The Regents of the University of California
    Inventors: Peter Burke, Ted Pham, Phi Pham
  • Mitochondrial Apoptotic Sensor
    Publication number: 20180120300
    Abstract: Mitochondria are central to the intrinsic apoptotic pathway of programmed cell death. Commitment to cell death occurs upon mitochondrial outer membrane permeabilization, and dysregulation of this vital apoptotic control point is implicated in various pathologies. Provided herein are novel sensors which can detect, in real time and with great sensitivity, the release of protons from intact mitochondria caused by mitochondrial outer membrane permeabilization. Embodiments include graphene based ion-sensitive field effect transistors.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 3, 2018
    Inventors: Peter Burke, Ted Pham, Phi Pham
  • Nanofluidic platform for single mitochondria analysis
    Patent number: 8895312
    Abstract: A microfluidic device for mitochondria analysis includes an inlet coupled to a first access channel, an outlet coupled to a second access channel, and a plurality of trapping channels fluidically coupled at one end to the first access channel and fluidically coupled at an opposing end to the second access channel, each trapping channel has a cross-sectional dimension about 2 ?m in one direction and a cross-sectional dimension between about 0.45 and about 0.75 ?m in a second direction.
    Type: Grant
    Filed: August 9, 2013
    Date of Patent: November 25, 2014
    Assignee: The Regents of the University of California
    Inventors: Peter Burke, Katayoun Zand, Ted Pham, Antonio Davila, Douglas Wallace
  • NANOFLUIDIC PLATFORM FOR SINGLE MITOCHONDRIA ANALYSIS
    Publication number: 20140051174
    Abstract: A microfluidic device for mitochondria analysis includes an inlet coupled to a first access channel, an outlet coupled to a second access channel, and a plurality of trapping channels fluidically coupled at one end to the first access channel and fluidically coupled at an opposing end to the second access channel, each trapping channel comprises a cross-sectional dimension about 2 ?m in one direction and a cross-sectional dimension between about 0.45 and about 0.75 ?m in a second direction.
    Type: Application
    Filed: August 9, 2013
    Publication date: February 20, 2014
    Inventors: Peter Burke, Katayoun Zand, Ted Pham, Antonio Davila, Douglas Wallace