Abstract: A kit for facilitating filling a hypodermic syringe from a medication vial and disposing of contaminated syringes includes a syringe-filling guide and a sharps holder. The guide has a base for retaining the syringe against relative movement as the syringe plunger is displaced. An attached cover is pivotally closed over the base and, as a vial is inserted into a channel in the base, the syringe needle pierces the vial stopper for drawing the medication therefrom. The cover includes a magnifying lens through which dosage indicia on the syringe are visible in enlarged condition to facilitate filling the syringe. The holder includes a base having a storage chamber, and a cover. A tray of the holder base closes the chamber and has an elongated slot and a plurality of resilient fingers adjacent the slot for supporting a contaminated syringe. As the holder cover closes over the tray, a pusher forces the syringe through the slot into the chamber.