Abstract: A method includes receiving toolface information corresponding to a location of the bottom hole assembly (BHA) with respect to a target drilling path and drift information. The surface steerable system calculates a first toolface vector from a first location of the BHA to the target drilling path to create a convergence path to the target drilling path and calculates an adjustment of the first toolface vector to a second toolface vector to account for system drift defined by the drift information such that the BHA will converge with the target drilling path by drilling in accordance with the second toolface vector. The surface steerable system modifies at least one drilling parameter to alter a drilling direction of the BHA based on the calculated second toolface vector and transmits the at least one drilling parameter to the drilling rig to target the BHA in accordance with the second toolface vector.

Abstract: A system and method for surface steerable drilling are provided. In one example, the system receives feedback information from a drilling rig and calculates an estimated position of a drill bit in a formation based on the feedback information. The system compares the estimated position to a desired position along a planned path of a borehole. The system calculates multiple solutions if the comparison indicates that the estimated position is outside a defined margin of error relative to the desired position. Each solution defines a path from the estimated position to the planned path. The system calculates a cost of each solution and selects one of the solutions based at least partly on the cost. The system produces control information representing the selected solution and outputs the control information for the drilling rig.

Abstract: A method for rotary steerable drilling, comprising calculating a first plurality of convergence plans if an estimated position of a drill bit is not within a defined margin of error of a desired point along a planned path for a borehole, calculating a second plurality of convergence plans if the estimated position of the drill bit is not within the margin of error, selecting a convergence plan that best satisfies a set of target parameters from the first and second plurality of convergence plans, producing a set of control parameters representing the selected convergence plan, transmitting one or more commands to one or more rotary steering components to actuate the one or more rotary steering components, in order to alter the planned path for the borehole in accordance with the set of control parameters, and drilling at least a portion of the borehole based on the set of control parameters.

Abstract: A method for determining geological formation characteristics involves driving a bottom hole assembly (BHA) in a borehole. At least one mechanical drilling parameter generated is detected responsive to operation of the BHA in the borehole. At least one geological formation characteristic is identified responsive to the detected at least one mechanical drilling parameter. The identified at least one geological formation characteristic is provided to a surface steerable drilling system. Operation of the surface steerable drilling system is controlled responsive to the at least one geological formation characteristic.

Abstract: A system and method for surface steerable drilling are provided. In one example, the system receives feedback information from a drilling rig and calculates an estimated position of a drill bit in a formation based on the feedback information. The system compares the estimated position to a desired position along a planned path of a borehole. The system calculates multiple solutions if the comparison indicates that the estimated position is outside a defined margin of error relative to the desired position. Each solution defines a path from the estimated position to the planned path. The system calculates a cost of each solution and selects one of the solutions based at least partly on the cost. The system produces control information representing the selected solution and outputs the control information for the drilling rig.

Abstract: A system and method for surface steerable drilling are provided. In one example, the system receives feedback information from a drilling rig and calculates an estimated position of a drill bit in a formation based on the feedback information. The system compares the estimated position to a desired position along a planned path of a borehole. The system calculates multiple solutions if the comparison indicates that the estimated position is outside a defined margin of error relative to the desired position. Each solution defines a path from the estimated position to the planned path. The system calculates a cost of each solution and selects one of the solutions based at least partly on the cost. The system produces control information representing the selected solution and outputs the control information for the drilling rig.

Abstract: A method includes receiving toolface information corresponding to a location of the bottom hole assembly (BHA) with respect to a target drilling path and drift information. The surface steerable system calculates a first toolface vector from a first location of the BHA to the target drilling path to create a convergence path to the target drilling path and calculates an adjustment of the first toolface vector to a second toolface vector to account for system drift defined by the drift information such that the BHA will converge with the target drilling path by drilling in accordance with the second toolface vector. The surface steerable system modifies at least one drilling parameter to alter a drilling direction of the BHA based on the calculated second toolface vector and transmits the at least one drilling parameter to the drilling rig to target the BHA in accordance with the second toolface vector.

Abstract: Provided are a system and method for calculating and selecting a convergence path based on cost. In one example, the method includes identifying multiple geometric convergence paths that each provides a convergence solution from a defined bottom hole assembly (BHA) location to a target path. A total monetary cost is calculated for each of the geometric convergence paths using an offset cost based on a distance of the geometric convergence path from the target path, a curvature cost based on an amount of curvature of the geometric convergence path, and a time cost based on an estimated amount of time needed to drill the geometric convergence path. The total monetary costs of the geometric convergence paths are compared and one of the geometric convergence paths is selected based on the total monetary cost of that geometric convergence path relative to the total monetary costs of the other geometric convergence paths.

Abstract: Provided are a system and method for calculating and selecting a convergence path based on cost. In one example, the method includes identifying multiple geometric convergence paths that each provides a convergence solution from a defined bottom hole assembly (BHA) location to a target path. A total monetary cost is calculated for each of the geometric convergence paths using an offset cost based on a distance of the geometric convergence path from the target path, a curvature cost based on an amount of curvature of the geometric convergence path, and a time cost based on an estimated amount of time needed to drill the geometric convergence path. The total monetary costs of the geometric convergence paths are compared and one of the geometric convergence paths is selected based on the total monetary cost of that geometric convergence path relative to the total monetary costs of the other geometric convergence paths.

Abstract: Provided are a system and method for calculating and selecting a convergence path based on cost. In one example, the method includes identifying multiple geometric convergence paths that each provides a convergence solution from a defined bottom hole assembly (BHA) location to a target path. A total monetary cost is calculated for each of the geometric convergence paths using an offset cost based on a distance of the geometric convergence path from the target path, a curvature cost based on an amount of curvature of the geometric convergence path, and a time cost based on an estimated amount of time needed to drill the geometric convergence path. The total monetary costs of the geometric convergence paths are compared and one of the geometric convergence paths is selected based on the total monetary cost of that geometric convergence path relative to the total monetary costs of the other geometric convergence paths.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: A system and method for surface steerable drilling are provided. In one example, the system receives toolface information for a bottom hole assembly (BHA) and non-survey sensor information corresponding to a location of the BHA in a borehole. The system calculates an amount of incremental progress made by the BHA based on the non-survey sensor information and calculates an estimate of the location based on the toolface information and the amount of incremental progress. The system repeats the steps of receiving toolface information and non-survey sensor information and calculating an amount of incremental progress to calculate an estimate of a plurality of locations representing a path of the BHA from a first survey point towards a second sequential survey point.

Abstract: A flexible light treatment head comprising one or more light source modules interconnected by a hinge apparatus along a flexing edge thereof. The light source modules have light emitting elements, such as LEDs or LASERs. The hinge apparatus comprises one or more hinges. Each hinge has a head wiring channel disposed to form a continuous wiring channel along the hinge apparatus. A head wiring channel is also provided for routing wires into the light source module.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.

Abstract: The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.

Abstract: The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.