Abstract: System and method for enabling application server request failover. For each application server request to be performed by a client computer, a requesting thread may be operable to utilize a custom wire-level communication protocol. Request failure detection mechanisms may be built into the custom wire-level communication protocol so that a requesting thread detects a failed request much sooner than if the thread utilized a standard communication protocol and relied on the client computer operating system for notification of failed requests. After sending a request to an application server, a requesting thread may be operable to “sleep” and then periodically wake up to poll the application server computer to determine whether the request has failed. If the requesting thread receives a response from the application server computer indicating that the request is not currently being processed, then the requesting thread may re-send the request.