Patents by Inventor Tellis A. Martin

Tellis A. Martin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Angiotensin-converting enzyme inhibiting dipeptide derivatives
    Patent number: 4617291
    Abstract: Dipeptides having the formula ##STR1## wherein A is halogen, hydrogen, lower alkyl, or lower alkoxy; B is hydrogen or lower alkyl, or A and B are taken together to form an ortho-methylene or ethylene bridge; R is hydrogen, lower alkyl, or phenylalkyl; and X.sup.1 and X.sup.2 are independently chosen from hydroxy or lower alkoxy; are inhibitors of angiotensin-converting enzyme and can be used for the treatment of hypertension in mammals.
    Type: Grant
    Filed: May 14, 1982
    Date of Patent: October 14, 1986
    Assignee: Mead Johnson & Company
    Inventors: Tellis A. Martin, Terence M. Dolak
  • Isoindole derivatives
    Patent number: 4600758
    Abstract: Novel phthalimide intermediates are reduced to 5-sulfamoyl-6-halo-3-oxoisoindole compounds bearing a substituted 1-phenylalkyl-4-piperidinyl moiety as the isoindole N-substitutent. Preferred compounds such as 6-chloro-2,3-dihydro-3-oxo-2-[1-(phenylmethyl)-4-piperidinyl]-1H-isoindole -5-sulfonamide exhibit diuretic and antihypertensive properties.
    Type: Grant
    Filed: November 1, 1984
    Date of Patent: July 15, 1986
    Assignee: Mead Johnson & Company
    Inventors: Terence M. Dolak, Tellis A. Martin
  • Isoindole diuretic derivatives, compositions and use
    Patent number: 4505911
    Abstract: The invention provides 3-oxoisoindole compounds useful as diuretics of the general formula ##STR1## wherein X is halogen or trifluoromethyl, A is alkylene (C.sub.2 -C.sub.4), R.sub.1 is alkyl, R.sub.2 is alkyl or phenylalkyl, or R.sub.1 and R.sub.2 taken together with nitrogen are piperidino, morpholino or pyridinyl.
    Type: Grant
    Filed: October 13, 1983
    Date of Patent: March 19, 1985
    Assignee: Mead Johnson & Company
    Inventors: Terence M. Dolak, Tellis A. Martin
  • Antihypertensive isoindole derivatives
    Patent number: 4495194
    Abstract: Novel phthalimide intermediates are reduced to 5-sulfamoyl-6-halo-3-oxoisoindole compounds bearing a substituted 1-phenylalkyl-4-piperidinyl moiety as the isoindole N-substituent. Preferred compounds such as 6-chloro-2,3-dihydro-3-oxo-2-[1-(phenylmethyl)-4-piperidinyl]-1H-isoindole -5-sulfonamide exhibit diuretic and antihypertensive properties.
    Type: Grant
    Filed: November 12, 1982
    Date of Patent: January 22, 1985
    Assignee: Mead Johnson & Company
    Inventors: Terence M. Dolak, Tellis A. Martin
  • Benzoic acid derivatives
    Patent number: 4178301
    Abstract: A mucolytic process is disclosed which comprises contacting N-(2-hydroxyethyl)mercaptoacetamidobenzamides or mercaptoacylamidobenzoic acids, mercaptoacetylsulfanilic acids and alkanoylthio derivatives thereof with mucus. Illustrative of compounds useful in the mucolytic process of the present invention are 4-(2-mercaptoacetamido)benzoic acid and N-(2-mercaptoacetyl)sulfanilic acid.
    Type: Grant
    Filed: October 16, 1978
    Date of Patent: December 11, 1979
    Assignee: Mead Johnson & Company
    Inventors: Tellis A. Martin, William T. Comer
  • Mercaptoacylamidobenzoylglycine mucolytic process and compositions
    Patent number: 4132803
    Abstract: N-[3-(mercaptoacetylamino)benzoyl]glycine, alkali metal and amine salts thereof are potent topically effective mucolytic agents.
    Type: Grant
    Filed: March 24, 1978
    Date of Patent: January 2, 1979
    Assignee: Mead Johnson & Company
    Inventor: Tellis A. Martin
  • Benzoic acid derivative and benzenesulfonic acid mucolytic process
    Patent number: 4132802
    Abstract: A mucolytic process is disclosed which comprises contacting N-(2-hydroxyethyl)mercaptoacetamidobenzamides or mercaptoacylamidobenzoic acids, mercaptoacetylsulfanilic acids and alkanoylthio derivatives thereof with mucus. Illustrative of compounds useful in the mucolytic process of the present invention are 4-(2-mercaptoacetamido)benzoic acid and N-(2-mercaptoacetyl)sulfanilic acid.
    Type: Grant
    Filed: March 24, 1978
    Date of Patent: January 2, 1979
    Assignee: Mead Johnson & Company
    Inventors: Tellis A. Martin, William T. Comer