Abstract: An array of reducing end-tagged carbohydrate molecules immobilised on a support. The reducing end-tagged carbohydrate molecules may be neoglycolipids or glycolipids. The reducing end-tagged carbohydrate molecule may have a carbohydrate which is an oligosaccharide, monosaccharide, an N-glycan, or an O-glycan. The array may comprise one or more samples of reducing end-tagged carbohydrate molecules which comprise a homogeneous sample of carbohydrate or a heterogeneous sample of carbohydrate. The carbohydrate may be derived from a microbe, a specific cell type, a specific tissue or organ, an animal, for example a human, or a plant.

Abstract: A biochemical reagent comprises an oligosaccharide, preferably one which has been liberated from an immunogenic glycoprotein or proteoglycan, which is immobilized on a carrier via an intermediate spacer molecule such as a lipid. The lipid molecule should preferably have at least two long lipid tails so that the oligosaccharide is held in spaced relationship to the carrier where is exhibits antibody-binding ability which is almost indistinguishable from that of the original glycoprotein or proteoglycan. The reagent has its application in biochemical testing of oligosaccharides and systems which bind to them.

Abstract: The invention relates to substitution derivatives of trisaccharide 3-fucosyl-N-acetyl lactosamine and to the immunological applications of these derivatives and of the trisaccharide itself particularly as diagnostic reagent and in therapy.