Abstract: A frame assembly includes a carrier and a frame. The carrier includes a bottom wall, and inner and outer side walls. The bottom wall is formed with an opening. The inner side wall is located in the opening. The inner and outer side walls extend from the bottom wall along an upright direction. The inner and outer side walls respectively include first inner and outer engaging structures. The outer side wall is spaced from the inner side wall. The frame includes a frame body, and inner and outer lateral walls. The inner and outer lateral walls extend from the frame body and respectively include second inner and outer engaging structures. The outer lateral wall is spaced from the inner lateral wall. The first and second inner engaging structures are engaged with each other, and the first and second outer engaging structures are engaged with each other.

Abstract: Embodiments of the present invention provide a light-emitting film, a light-emitting film array, a micro-light emitting diode (LED) array, and their manufacturing methods. In one embodiment, epitaxial layers are formed on a substrate, and a conversion film is formed on a corresponding epitaxial layer. Pixels can be defined through lithography with a very small pixel size. A mass transfer is unnecessary for this method. The produced light-emitting films and the conversion films are homogeneous films and are insoluble in water, and the manufacturing steps can be simplified due to the waterproofing function of the films.

Abstract: A frame assembly includes a carrier and a frame. The carrier includes a bottom wall, and inner and outer side walls. The bottom wall is formed with an opening. The inner side wall is located in the opening. The inner and outer side walls extend from the bottom wall along an upright direction. The inner and outer side walls respectively include first inner and outer engaging structures. The outer side wall is spaced from the inner side wall. The frame includes a frame body, and inner and outer lateral walls. The inner and outer lateral walls extend from the frame body and respectively include second inner and outer engaging structures. The outer lateral wall is spaced from the inner lateral wall. The first and second inner engaging structures are engaged with each other, and the first and second outer engaging structures are engaged with each other.

Abstract: The present disclosure relates to novel glycosynthase enzymes for glycoprotein engineering and/or homogeneous antibody remodeling. The enzyme variants, termed EndoSd-D232M and EndoSz-D234M, contain the glycan conjugation and/or modification activity at the conserved N297 glycosylation site of Fc region of an exemplary antibody. It has been demonstrated that the glycosynthase activities of EndoSd-D232M and EndoSz-D234M can be applied to various mAbs targeting different receptors, including, but not limited to, Globo H, SSEA-4, SSEA-3 series of receptors (OBI-888; Globo H ganglioside), Herceptin (Her 2 receptor), Perj eta (Her 2 receptor) and Vectibix (EGFR receptor). It has been found that both mAb-GlcNAc and mAb-GlucNAc(F) were suitable substrates for both EndoSd-D232M and EndoSz-D234M. The ADCC assay of related products, OBI-888-G2S2 and Herceptin-G2S2, showed that the remodeled homogeneous antibody, mAb-G2S2, has an increased relative activity ranging from 3 to 26 folds.

Abstract: A backlight module includes a carrying member, a light source, a light guide plate, a fixing frame and an outer component. The light source is disposed on the carrying member. The light guide plate is disposed on the carrying member, in which a light-incident surface of the light guide plate is disposed adjacent to the light source. The fixing frame fixed on a bottom portion of the carrying member along a first direction. The outer component is fixed on the fixing frame along a second direction.

Abstract: A backlight module includes a carrying member, a light source, a light guide plate, a fixing frame and an outer component. The light source is disposed on the carrying member. The light guide plate is disposed on the carrying member, in which a light-incident surface of the light guide plate is disposed adjacent to the light source. The fixing frame fixed on a bottom portion of the carrying member along a first direction. The outer component is fixed on the fixing frame along a second direction.

Abstract: Antibody drug conjugates (ADC's) comprising a drug moiety/payload conjugated to antibody or antigen binding fragments thereof that bind to Globo series antigen disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The antibodies of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the antibodies disclosed herein can include carcinomas, such as sarcoma, skin cancer, leukemia, lymphoma, brain cancer, glioblastoma, lung cancer, breast cancer, oral cancer, head-and-neck cancer, nasopharyngeal cancer, esophagus cancer, stomach cancer, liver cancer, bile duct cancer, gallbladder cancer, bladder cancer, pancreatic cancer, intestinal cancer, colorectal cancer, kidney cancer, cervix cancer, endometrial cancer, ovarian cancer, testical cancer, buccal cancer, oropharyngeal cancer, laryngeal cancer and prostate cancer.

Abstract: A light assembly, a backlight module and a liquid crystal display are described. The light assembly includes a carrier, a light guide plate, a light source, a constraining member and a securing unit. The light guide plate is disposed on the carrier and has an incident surface. The light source which emits light towards the light guide plate and is adjacent to the incident surface of the light guide plate. The constraining member is disposed above the carrier and has a constraining surface. The securing unit is used to combine the constraining member with the carrier while the light guide plate is restrained against movement by the constraining surface of the constraining member.

Abstract: The present disclosure relates to novel glycosynthase enzymes for glycoprotein engineering and/or homogeneous antibody remodeling. The enzyme variants, termed EndoSd-D232M and EndoSz-D234M, contain the glycan conjugation and/or modification activity at the conserved N297 glycosylation site of Fc region of an exemplary antibody. It has been demonstrated that the glycosynthase activities of EndoSd-D232M and EndoSz-D234M can be applied to various mAbs targeting different receptors, including, but not limited to, Globo H, SSEA-4, SSEA-3 series of receptors (OBI-888; Globo H ganglioside), Herceptin (Her 2 receptor), Perjeta (Her 2 receptor) and Vectibix (EGFR receptor). It has been found that both mAb-GlcNAc and mAb-GlucNAc(F) were suitable substrates for both EndoSd-D232M and EndoSz-D234M. The ADCC assay of related products, OBI-888-G2S2 and Herceptin-G2S2, showed that the remodeled homogeneous antibody, mAb-G2S2, has an increased relative activity ranging from 3 to 26 folds.

Abstract: A back plate assembly and a backlight module are provided. The back plate assembly includes a back plate, at least one optical film and at least one fixing member. The back plate includes a bottom plate and a sidewall. The optical film is disposed on the bottom plate. The fixing member includes a main body and a protruding member. At least one portion of the main body overlaps with the sidewall. The protruding member is disposed on the main body and is combined with the optical film.

Abstract: A light assembly, a backlight module and a liquid crystal display are described. The light assembly includes a carrier, a light guide plate, a light source, a constraining member and a securing unit. The light guide plate is disposed on the carrier and has an incident surface. The light source which emits light towards the light guide plate and is adjacent to the incident surface of the light guide plate. The constraining member is disposed above the carrier and has a constraining surface. The securing unit is used to combine the constraining member with the carrier while the light guide plate is restrained against movement by the constraining surface of the constraining member.

Abstract: A light assembly, a backlight module and a liquid crystal display are described. The light assembly includes a carrier, a light guide plate, a light source, a constraining member and a securing unit. The light guide plate is disposed on the carrier and has an incident surface. The light source which emits light towards the light guide plate and is adjacent to the incident surface of the light guide plate. The constraining member is disposed above the carrier and has a constraining surface. The securing unit is used to combine the constraining member with the carrier while the light guide plate is restrained against movement by the constraining surface of the constraining member.

Abstract: A coater includes a chuck, a source of a coating material, a dispensing head, an exhaust system, and a liner. The chuck is configured to support a wafer. The dispensing head is configured to dispense the coating material onto the wafer. The exhaust system is configured to exhaust the excess coating material. The liner is present at least partially on an inner surface of the exhaust system. The liner has a stick resistance to the coating material, and the stick resistance of the liner is greater than a stick resistance of the inner surface of the exhaust system.

Abstract: A back plate assembly and a backlight module are provided. The back plate assembly includes a back plate, at least one optical film and at least one fixing member. The back plate includes a bottom plate and a sidewall. The optical film is disposed on the bottom plate. The fixing member includes a main body and a protruding member. At least one portion of the main body overlaps with the sidewall. The protruding member is disposed on the main body and is combined with the optical film.

Abstract: A back plate assembly and a backlight module are provided. The back plate assembly includes a back plate, at least one optical film and at least one fixing member. The back plate includes a bottom plate and a sidewall. The optical film is disposed on the bottom plate. The fixing member includes a main body and a protruding member. At least one portion of the main body overlaps with the sidewall. The protruding member is disposed on the main body and is combined with the optical film.

Abstract: A coater includes a chuck, a source of a coating material, a dispensing head, an exhaust system, and a liner. The chuck is configured to support a wafer. The dispensing head is configured to dispense the coating material onto the wafer. The exhaust system is configured to exhaust the excess coating material. The liner is present at least partially on an inner surface of the exhaust system. The liner has a stick resistance to the coating material, and the stick resistance of the liner is greater than a stick resistance of the inner surface of the exhaust system.

Abstract: A backlight module includes a frame structure, a heat sink, a light source and a light guiding plate. The frame structure includes a cover unit that defines an airgap therein. The heat sink is located below the airgap of the cover unit. The light source directly contacts the heat sink. The light guiding plate is disposed to correspond in position to the light source for receiving light emitted from the light source. The heat sink is located between the light guiding plate and the cover unit.

Abstract: A backlight module includes a frame structure, a heat sink, a light source and a light guiding plate. The frame structure includes a cover unit that defines an airgap therein. The heat sink is located below the airgap of the cover unit. The light source directly contacts the heat sink. The light guiding plate is disposed to correspond in position to the light source for receiving light emitted from the light source. The heat sink is located between the light guiding plate and the cover unit.

Abstract: A back plate assembly and a backlight module are provided. The back plate assembly includes a back plate, at least one optical film and at least one fixing member. The back plate includes a bottom plate and a sidewall. The optical film is disposed on the bottom plate. The fixing member includes a main body and a protruding member. At least one portion of the main body overlaps with the sidewall. The protruding member is disposed on the main body and is combined with the optical film.

Abstract: A light assembly, a backlight module and a liquid crystal display are described. The light assembly includes a carrier, a light guide plate, a light source, a constraining member and a securing unit. The light guide plate is disposed on the carrier and has an incident surface. The light source which emits light towards the light guide plate and is adjacent to the incident surface of the light guide plate. The constraining member is disposed above the carrier and has a constraining surface. The securing unit is used to combine the constraining member with the carrier while the light guide plate is restrained against movement by the constraining surface of the constraining member.