Patents by Inventor Teresa B. Hong

Teresa B. Hong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant lectin and uses thereof
    Patent number: 11767351
    Abstract: Disclosed herein are a recombinant Streptomyces S27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens.
    Type: Grant
    Filed: August 4, 2021
    Date of Patent: September 26, 2023
    Assignee: CITY OF HOPE
    Inventors: Markus Kalkum, Yoko Fujita-Yamaguchi, Karine Bagramyan, Teresa B. Hong, Sarah Shuck
  • LIPOSOMAL ENHANCED INTRA-PERITONEAL CHEMOTHERAPY
    Publication number: 20220000777
    Abstract: The invention described herein is directed to treating neoplasms by intraperitoneal administration of liposomal formulations of chemotherapeutic drugs. Methods of instilling liposomal formulations of taxane and platin chemotherapeutic agents into the peritoneal cavity of a subject to treat ovarian cancer or a primary peritoneal cancer are disclosed.
    Type: Application
    Filed: November 4, 2019
    Publication date: January 6, 2022
    Inventors: Michael G. OEFELEIN, Natarajan VENKATESAN, Nitin K. SWARNAKAR, Teresa B. HONG, Guru V. BETAGERI, Ramachandran THIRUCOTE, Lining Zhu HUTCHINSON
  • RECOMBINANT LECTIN AND USES THEREOF
    Publication number: 20210395315
    Abstract: Disclosed herein are a recombinant Streptomyces S27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens.
    Type: Application
    Filed: August 4, 2021
    Publication date: December 23, 2021
    Applicant: CITY OF HOPE
    Inventors: Markus KALKUM, Yoko FUJITA-YAMAGUCHI, Karine BAGRAMYAN, Teresa B. HONG, Sarah SHUCK
  • RECOMBINANT LECTIN AND USES THEREOF
    Publication number: 20190233479
    Abstract: Disclosed herein are a recombinant Streptomyces S27S5 hemagglutinin (SHA), and homologues thereof, and a fusion protein of a fluorescent protein (such as GFP and mCherry1) and SHA or a homologue thereof, which specifically bind to carbohydrates, including oligomeric sugars that terminate in L-rhamnose or D-galactose. The SHA, SHA homologues, and fusion proteins can be used to detect a variety of microorganisms or cancer or tumor antigens.
    Type: Application
    Filed: October 19, 2018
    Publication date: August 1, 2019
    Inventors: Markus KALKUM, Yoko FUJITA-YAMAGUCHI, Karine BAGRAMYAN, Teresa B. HONG, Sarah SHUCK
  • vaccine preparation and methods of making and using thereof
    Patent number: 8449894
    Abstract: The present invention relates to compositions and methods in preventing and/or treating diseases caused by Aspergillus. In particular, the present invention is directed to Aspergillus vaccine preparations and methods of making and using thereof.
    Type: Grant
    Filed: May 25, 2007
    Date of Patent: May 28, 2013
    Assignee: City of Hope
    Inventors: Markus Kalkum, Diana Diaz-Arevalo, James I. Ito, Joseph M. Lyons, Teresa B. Hong
  • Retrocyclins: antiviral and antimicrobial peptides
    Patent number: 7718610
    Abstract: Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
    Type: Grant
    Filed: January 1, 2008
    Date of Patent: May 18, 2010
    Assignee: The Regents of the University of California
    Inventors: Robert I. Lehrer, Alan J. Waring, Alexander M. Cole, Teresa B. Hong
  • RETROCYCLINS: ANTIVIRAL AND ANTIMICROBIAL PEPTIDES
    Publication number: 20090264344
    Abstract: Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
    Type: Application
    Filed: January 1, 2008
    Publication date: October 22, 2009
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: ROBERT I. LEHRER, ALAN J. WARING, ALEXANDER M. COLE, TERESA B. HONG
  • Retrocyclins: antiviral and antimicrobial peptides
    Patent number: 7314858
    Abstract: Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
    Type: Grant
    Filed: November 5, 2004
    Date of Patent: January 1, 2008
    Assignee: The Regents of the University of California
    Inventors: Robert I. Lehrer, Alan J. Waring, Alexander M. Cole, Teresa B. Hong
  • Retrocyclins: antiviral and antimicrobial peptides
    Patent number: 6713078
    Abstract: Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
    Type: Grant
    Filed: May 6, 2002
    Date of Patent: March 30, 2004
    Assignee: The Regents of the University of California
    Inventors: Robert I. Lehrer, Alan J. Waring, Alexander M. Cole, Teresa B. Hong
  • Retrocyclins: antiviral and antimicrobial peptides
    Publication number: 20030144184
    Abstract: Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical composition comprising retrocyclin as an active agent is administered therapeutically to a patient suffering from a bacterial and/or viral infection, or to an individual facing exposure to a bacterial and/or viral infection, especially one caused by the HIV-1 retrovirus or other sexually-transmitted pathogens.
    Type: Application
    Filed: May 6, 2002
    Publication date: July 31, 2003
    Inventors: Robert I. Lehrer, Alan J. Waring, Alexander M. Cole, Teresa B. Hong