Abstract: Example embodiments of the systems and methods of magnetic clasping disclosed herein include a a self-aligning interlocking magnetic clasp. When the two halves are placed within close proximity of each other, the magnetic attraction of the magnets within the clasps orient the parts, and the mechanical features of a key, a keyway and a sliding face align. These features hold the two clasps together with the opposed sliding faces coincident and the keys and keyways interlocked, forming a bead shape, for example, with a hole through the middle.

Abstract: Example embodiments of the systems and methods of magnetic clasping disclosed herein include a a self-aligning interlocking magnetic clasp. When the two halves are placed within close proximity of each other, the magnetic attraction of the magnets within the clasps orient the parts, and the mechanical features of a key, a keyway and a sliding face align. These features hold the two clasps together with the opposed sliding faces coincident and the keys and keyways interlocked, forming a bead shape, for example, with a hole through the middle.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. In one embodiment the device is a micrometer assisted fluid delivery device comprising a micrometer, a holder portion, and a syringe. The micrometer assisted delivery device is designed to control the amount of the solution that can be aspirated and delivered and the rate at which material is aspirated and dispensed from a syringe into tissue. The invention also provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: The present invention provides fluid and material delivery methods and devices for practicing the methods. The invention provides a method of delivering cellular material comprising injecting the cellular material into a subject such that the injected cells retain their inherent morphologic characteristics upon injection. The method comprises the steps of aspirating the cellular material into a fluid delivery device which incorporates a syringe arrangement. The cellular material is aspirated into the main body of the syringe until the desired amount of a material has filled the syringe body. The needle of the fluid delivery device is then inserted into the skin of a subject at an angle about parallel to the skin until a desired depth has been reached. The cellular material is then injected in the subject until the desired volume of material has been injected. The needle of the device is then rotated approximately 45 to 90 degrees and the needle is removed from the injection site.

Abstract: An implant for marking a location within the tissue of a patient after biopsy is self-anchoring. In one embodiment a strip of a shape memory alloy such as Nitinol can be straightened to facilitate insertion through a small gauge needle but, once exposed within the tissue to body temperature, assumes a helical coil configuration, thereby mechanically clamping to the tissue. In other embodiments the implants include barbs of resilient, deformable metal which can be straightened for insertion into a small gauge needle, but once the implant exits the forward end of the needle the barbs spring outward, anchoring the implant within the tissue. A method for implanting a plurality of markers within the tissues of a patient involves a needle having a plurality of markers sequentially loaded therewithin. The forward end of the needle is inserted into the tissues of the patient and advanced to a first target location, at which point a first marker is ejected into the tissues of the patient.

Abstract: An automated tissue sampling device is disclosed which permits its needles to be cocked either simultaneously or sequentially and can be cocked with only one hand. The cocking mechanism is arranged so as to virtually eliminate the possibility that the needles will be cocked in the wrong sequence. The physician can readily confirm, either visually or tactilely, whether the device is uncocked, half cocked, or fully cocked. The disclosed tissue sampling device also comprises two different trigger buttons, one adjacent the front end of the device and the other at the rear, and manipulating either of the two trigger buttons will actuate the device.

Abstract: An automated tissue sampling device is disclosed which permits its needles to be cocked either simultaneously or sequentially and can be cocked with only one hand. The cocking mechanism is arranged so as to virtually eliminate the possibility that the needles will be cocked in the wrong sequence. The physician can readily confirm, either visually or tactilely, whether the device is uncocked, half cocked, or fully cocked. The disclosed tissue sampling device also comprises two different trigger buttons, one adjacent the front end of the device and the other at the rear, and manipulating either of the two trigger buttons will actuate the device.