Abstract: Novel reduction compositions are prepared from an active hydride, an additive, and a Lewis base in a hydrocarbon solvent. Such compositions can provide a superior reducing system for organic substrates.

Abstract: Organometallic amide compositions and processes for preparing the same, for example, by: reacting an alkali metal, alkali metal hydride, or alkali metal amide with a substituted amine in the absence of an electron carrier; reacting an alkali metal with a substituted amine in the presence of an electron carrier in a hydrocarbon solvent; distilling a composition which includes an alkali metal amide and a reduced electron carrier to recover the alkali metal amide; reacting an alkali metal with a substituted amine in the presence of an alkyl halide; and reacting a substituted amine capable of reacting with an alkali metal to form a hydrocarbon insoluble alkali metal amide with an alkali metal in the presence of a substituted amine capable of reacting with an alkali metal to form a hydrocarbon soluble alkali metal amide.

Abstract: A process for preparing high purity solutions of highly substituted lithium amide bases by direct reaction of lithium metal with highly substituted amine bases alone or in an ether solvent, a hydrocarbon solvent or in a mixed ether/hydrocarbon solvent mixture, optionally in the presence of a catalyst selected from tin salts and transition metal salts of Groups 4B, 5B, 6B, 7B, and 8 of the Periodic Table.

Abstract: This invention concerns organometallic amide compositions particularly bimetallic organoamides in liquid hydrocarbon solutions in which one metal is an alkali metal the other an alkaline earth metal, zinc or copper and particularly lithium magnesium bis-diorganoamides, such as lithium magnesium bis-diisopropylamide and processes for preparation of such amides. These novel bimetallic amides have increased solubility in liquid hydrocarbon solvents and improved thermal and precipitation stability at temperatures of 0.degree. C. to 40.degree. C.

Abstract: A process for producing organometallic compositions by reacting an organohalide with a mixture of two metals; one being an alkali metal, the other being selected from magnesium, calcium, barium and zinc in a hydrocarbon solvent containing 0.5 to 2.0 moles of a Lewis Base per mole of organohalide.

Abstract: This invention concerns organometallic amide compositions particularly bimetallic organoamides in liquid hydrocarbon solutions in which one metal is an alkali metal the other an alkaline earth metal, zinc or copper and particularly lithium magnesium bis-diorganoamides, such as lithium magnesium bis-diisopropylamide and processes for preparation of such amides. These novel bimetallic amides have increased solubility in liquid hydrocarbon solvents and improved thermal and precipitation stability at temperatures of 0.degree. C. to 40.degree. C.

Abstract: A process for producing organometallic compositions by reacting an organohalide with a mixture of two metals; one being an alkali metal, the other being selected from magnesium, calcium, barium and zinc in a hydrocarbon solvent containing 0.5 to 2.0 moles of a Lewis Base per mole of organohalide.

Abstract: An ether free magnesium bisorganoamide of the formulaMg[N(R.sup.1) (R.sup.2)].sub.2wherein R.sup.1 and R.sup.2 are independently selected from hydrogen and alkyl groups containing 2 to 20 carbon atoms with the proviso that at least one of R.sup.1 and R.sup.2 is other than hydrogen or R.sup.1 and R.sup.2 taken together form an alkylene chain of 4 to 20 carbon atoms and a method of manufacture. Also disclosed are lithium-magnesiumorganoamides and organosubstituted lithium-magnesiumorganoamide.

Abstract: The present invention provides a nonpyrophoric and thermally stable form of lithium diisopropylamide which is useful as a reagent in the preparation of pharmaceuticals and specialty chemicals. The preferred composition includes lithium diisopropylamide, a limited amount of tetrahydrofuran in an amount not exceeding one mole per mole of lithium diisopropylamide, and at least one C.sub.2 to C.sub.18 amine.

Abstract: 2-Ketoalkyl-4(3H)-quinazolinones of the formula ##STR1## wherein R.sub.1 is an aliphatic, cycloaliphatic or hydrocarbon aromatic group of 1-10 carbon atoms;A is divalent alkylene of 1 to 10 carbon atoms;R.sub.2 is an aliphatic, cycloaliphatic, hydrocarbon aromatic or heterocyclic group of 1-10 carbon atoms formed by condensing an acyl ester of the formula R.sub.2 COOR' which can be dissociated to form --COR.sub.2 and R'OH in which R' is the alcoholic portion of said ester; andR.sub.3 and R.sub.4 are each hydrogen, hydroxy, amino, halogen, trifluoromethyl, alkyl, alkoxy, alkylthio or alkylsulfonyl each of 1-4 carbon atoms, the substituents other than hydrogen when present being preferably in the 6- and/or 7-position of the quinazolinone nucleusprovide compounds having useful activity as CNS depressants and anticonvulsants.