Abstract: The present invention relates to live attenuated Salmonella cultures for use as vaccines. The Salmonella cultures of the present invention have a substantially reduced capacity to grow and replicate in the presence of bile. The reduced capacity for growth is due to a metabolic-drift mutation induced by exposure to a combination of nalidixic acid and rifampicin for a time and under conditions sufficient to induce the mutation.

Abstract: The present invention relates to live attenuated Salmonella cultures for use as vaccines. The Salmonella cultures of the present invention have a substantially reduced capacity to grow and replicate in the presence of bile. The reduced capacity for growth is due to a metabolic-drift mutation induced by exposure to a combination of nalidixic acid and rifampicin for a time and under conditions sufficient to induce the mutation.

Abstract: Process for producing a polyglycidylamino compound characterized by comprising:(I) an addition reaction step at which a diamine is reacted with an excess amount, based on diamine, of an epihalohydrin in the presence of water,(II) a primary dehydrohalogenatin reaction step at which the addition reaction mixture from the step (I) is reacted with a halogen-removing agent in the co-presence of at least one phase transfer catalyst,(III) a step at which the dehydrohalogenation reaction mixture from the step (II) is separated into an organic phase and a water phase by adding water thereto, and an unreacted epihalohydrin is distilled off from the organic phase,(IV) a step at which the reaction mixture from the step (II) is washed with water,(V) a secondary dehydrohalogenation reaction step at which the crude polyglycidylamino compound from the step (IV) is reacted with a halogen-removing agent in the co-presence of at least one phase transfer catalyst, and(VI) a step at which the dehydrohalogenation reaction mixture

Abstract: In case of detecting tire information marks engraved in a side wall portion of tire in the form of protrusion or recess, width and inner diameter of tire are detected to provide a tire size signal, after a first camera head is driven into a given position in accordance with the tire side signal, an identification mark engraved in the size wall portion of tire is optically detected by the first camera head to derive a position signal, and after a second camera head is driven into a given position in accordance with the position signal, the tire information marks are optically detected by the second camera head to derive a tire information signal. In this manner, the tire information marks can be detected in a rapid and accurate manner.

Abstract: Tire information marks for denoting tire kind, tire size, etc. formed in a surface of side wall of tire as protrusion or groove having a triangular cross section are optically detected by illuminating the surface of side wall of tire from a first direction substantially perpendicular to the surface of side wall of tire and a second direction inclined with respect to the surface of side wall of tire, and picking up an image of the surface of side wall of tire thus illuminated from the two different directions to derive an image signal. The image signal thus derived is converted into a bivalent signal, and is thinned to produce a mark pattern. Then the mark pattern is compared with a thick standard mark pattern. When a substantial part of the detected mark pattern is included in the standard mark pattern, the detected mark pattern is recognized to be identical with the standard mark pattern.