Patents by Inventor Tetsuro Ogawa
Tetsuro Ogawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7214635Abstract: A bioactive glass having a composition substantially comprising 20 to 40 mol % of CaO, 40 to 60 mol % of SiO2, and 10 to 20 mol % of MgO is high in bioactivity and mechanical strength, and a sintered calcium phosphate glass using the bioactive glass as a sintering aid is excellent in biocompatibility and mechanical strength.Type: GrantFiled: October 13, 2004Date of Patent: May 8, 2007Assignees: PENTAX CorporationInventors: Yukiko Gonda, Tetsuro Ogawa, Tadashi Kokubo
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Publication number: 20050079226Abstract: A bioactive glass having a composition substantially comprising 20 to 40 mol % of CaO, 40 to 60 mol % of SiO2, and 10 to 20 mol % of MgO is high in bioactivity and mechanical strength, and a sintered calcium phosphate glass using the bioactive glass as a sintering aid is excellent in biocompatibility and mechanical strength.Type: ApplicationFiled: October 13, 2004Publication date: April 14, 2005Applicants: PENTAX Corporation, Tadashi KOKUBOInventors: Yukiko Gonda, Tetsuro Ogawa, Tadashi Kokubo
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Publication number: 20040087429Abstract: A bioactive glass having a composition substantially comprising 30 to 60 mol % of CaO, 40 to 70 mol % of SiO2 and 20 mol % or less of Na2O has low glass transition temperature, and/or crystallization temperature, and a sintered calcium phosphate glass obtained by using the bioactive glass as a sintering aid has excellent biocompatibility, mechanical strength and sinterability.Type: ApplicationFiled: July 15, 2003Publication date: May 6, 2004Applicants: PENTAX Corporation, Tadashi KOKUBOInventors: Tetsuro Ogawa, Tadashi Kokubo
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Patent number: 6306297Abstract: Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof. A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 &mgr;m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 &mgr;m. A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca10(PO4)6(OH)2, Ca3(PO4)2, Ca2P2O7, Ca(PO3)2, Ca10(PO4)6F2 and Ca10(PO4)6Cl2, said packing material having a dense structure with a porosity of no more than 5%.Type: GrantFiled: January 11, 1995Date of Patent: October 23, 2001Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Takeshi Ichitsuka, Tetsuro Ogawa, Masaya Sumita, Akihiko Yokoo, Katsumi Kawamura
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Patent number: 5897953Abstract: A granular polymer composite comprising polymeric granules having coated on a surface thereof a calcium phosphate compound, at least a part of the particles of the calcium phosphate compound penetrates into the polymeric granules. The composite has a high bonding strength between the polymeric granules as a matrix and a coating of the calcium phosphate compound and also can fully exhibit the functions of a calcium phosphate compound. Using the granular polymer composite, a diagnostic agent which comprises of an antigen or antibody is adsorbed and immobilized on the composite and is therefore useful in diagnostic tests utilizing an antigen-antibody reaction for a number of infectious diseases.Type: GrantFiled: March 25, 1996Date of Patent: April 27, 1999Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Tetsuro Ogawa, Tsuneo Hiraide
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Patent number: 5851670Abstract: In vivo-soluble composite particles involving a particle of a polymeric substance such as polylactic acid and the like soluble in a living body, having coated on a surface thereof, a calcium phosphate compound having a Ca/P ratio of about 1.0 to 2.0. The in vivo-soluble composite particles have a highly increased adsorptivity with regard to medicaments, antigens and others and also the in vivo-soluble composite particles can be dissolved or decomposed in the living body without producing a remainder in the body.Type: GrantFiled: January 29, 1997Date of Patent: December 22, 1998Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Ayumi Mitoh, Tetsuro Ogawa
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Patent number: 5827669Abstract: A detection sheet capable of detecting an antigen or antibody in a biological fluid with a high sensitivity in a simple operation, as well as a detection kit and detection method using the detection sheet. The detection sheet comprises (a) a fibrous aggregate with carried particles of a calcium phosphate compound having an average particle diameter of about 0.01 to 200 microns and a Ca/P ratio of about 1.0 to 2.0, and (b) an avidin, streptavidin or avidin derivative from which carbohydrates have been extracted immobilized on said calcium phosphate compound. After a biotinylated antigen or antibody is bonded to the immobilized avidin, streptavidin, or avidin derivative of the detection sheet, the detection sheet is contacted with a test solution to thereby bond an antigen or antibody of the test solution to the detection sheet.Type: GrantFiled: November 12, 1996Date of Patent: October 27, 1998Assignees: Nakayama, Mikio, Kitana, Tadahiko, Asahi Kogaku Kogyo Kabushiki KaishaInventors: Mikio Nakayama, Tadahiko Kitano, Ayumi Mitoh, Tetsuro Ogawa, Tsuneo Hiraide
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Patent number: 5736099Abstract: A test plate for an agglutination test which comprises a plate with a plurality of wells formed thereon, each of the wells having adhered to a surface thereof a protein A and/or a protein G. The agglutination test plate, according to the present invention, when used in an agglutination test, can ensure a clear judgment concerning the formation of an agglutinative image or a non-agglutinative image, along with a good determination sensitivity. A process for the production of such an agglutination test plate is also provided.Type: GrantFiled: December 28, 1995Date of Patent: April 7, 1998Assignees: Asahi Kogaku Kogyo Kabushiki Kaisha, Tadahiko Kitano, Mikio NakayamaInventors: Tsuneo Hiraide, Tetsuro Ogawa, Ayumi Mitoh, Tadahiko Kitano, Mikio Nakayama
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Patent number: 5651882Abstract: Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof.A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 .mu.m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 .mu.m.A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2, Ca.sub.3 (PO.sub.4).sub.2, Ca.sub.2 P.sub.2 O.sub.7, Ca(PO.sub.3).sub.2, Ca.sub.10 (PO.sub.4).sub.6 F.sub.2 and Ca.sub.10 (PO.sub.4).sub.6 Cl.sub.Type: GrantFiled: January 11, 1995Date of Patent: July 29, 1997Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Takeshi Ichitsuka, Tetsuro Ogawa, Katsumi Kawamura, Akihiko Yokoo
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Patent number: 5651884Abstract: Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof.A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 .mu.m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 .mu.m.A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2, Ca.sub.3 (PO.sub.4).sub.2, Ca.sub.2 P.sub.2 O.sub.7, Ca(PO.sub.3).sub.2, Ca.sub.10 (PO.sub.4).sub.6 F.sub.2 and Ca.sub.10 (PO.sub.4).sub.6 Cl.sub.Type: GrantFiled: June 6, 1995Date of Patent: July 29, 1997Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Takeshi Ichitsuka, Tetsuro Ogawa, Katsumi Kawamura, Masaya Sumita, Akihiko Yokoo
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Patent number: 5567231Abstract: Deodorant comprising 5 to 100% by weight of a calcium phosphate compound having a molar ratio of Ca/P of 0.8 to 2.0, a deodorant sheet and filter sheet containing such calcium phosphate compound, and a functional paper containing 10 to 80% by weight of a calcium phosphate compound. A filtering medium for an exhaust gas comprises a ceramic material containing 5 to 100% by weight of a calcium phosphate compound, as well as a filter cartridge and exhaust gas filter containing the filtering medium. Based on the excellent properties of the incorporated calcium phosphate compound, the agents and products according to the present invention exhibit a highly improved adsorptivity to oil-soluble substances, odor substances, animal or vegetable cells, viruses, biopolymeric substances or other substances, and therefore can be advantageously used in various fields of technology. For example, the functional paper can be used as a deodorant, filter medium and adsorbent as well as a flame-retardant paper.Type: GrantFiled: February 14, 1995Date of Patent: October 22, 1996Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Akihiko Yokoo, Tetsuro Ogawa
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Patent number: 5545240Abstract: Deodorant comprising 5 to 100% by weight of a calcium phosphate compound having a molar ratio of Ca/P of 0.8 to 2.0, a deodorant sheet and filter sheet containing such calcium phosphate compound, and a functional paper containing 10 to 80% by weight of a calcium phosphate compound. A filtering medium for an exhaust gas comprises a ceramic material containing 5 to 100% by weight of a calcium phosphate compound, as well as a filter cartridge and exhaust gas filter containing the filtering medium. Based on the excellent properties of the incorporated calcium phosphate compound, the agents and products according to the present invention exhibit a highly improved adsorptivity to oil-soluble substances, odor substances, animal or vegetable cells, viruses, biopolymeric substances or other substances, and therefore can be advantageously used in various fields of technology. For example, the functional paper can be used as a deodorant, filter medium and adsorbent as well as a flame-retardant paper.Type: GrantFiled: February 14, 1995Date of Patent: August 13, 1996Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Sumiaki Tsuru, Akihiko Yokoo, Takeshi Sakurai, Tetsuro Ogawa
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Patent number: 5540995Abstract: A granular polymer composite comprising polymeric granules having coated on a surface thereof a calcium phosphate compound, at least a part of the particles of the calcium phosphate compound penetrates into the polymeric granules. The composite has a high bonding strength between the polymeric granules as a matrix and a coating of the calcium phosphate compound and also can fully exhibit the functions of a calcium phosphate compound. Using the granular polymer composite, a diagnostic agent which comprises of an antigen or antibody is adsorbed and immobilized on the composite and is therefore useful in diagnostic tests utilizing an antigen-antibody reaction for a number of infectious diseases.Type: GrantFiled: October 5, 1994Date of Patent: July 30, 1996Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Tadahiko Kitano, Mikio Nakayama, Tetsuro Ogawa, Tsuneo Hiraide
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Patent number: 5441635Abstract: Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof.A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 .mu.m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 .mu.m.A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2, Ca.sub.3 (PO.sub.4).sub.2, Ca.sub.2 P.sub.2 O.sub.7, Ca(PO.sub.3).sub.2, Ca.sub.10 (PO.sub.4).sub.6 F.sub.2 and Ca.sub.10 (PO.sub.4).sub.6 Cl.sub.Type: GrantFiled: March 10, 1993Date of Patent: August 15, 1995Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Takeshi Ichitsuka, Tetsuro Ogawa, Masaya Sumita
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Patent number: 5310548Abstract: Deodorant comprising 5 to 100% by weight of a calcium phosphate compound having a molar ratio of Ca/P of 0.8 to 2.0, a deodorant sheet and filter sheet containing such calcium phosphate compound, and a functional paper containing 10 to 80% by weight of a calcium phosphate compound. A filtering medium for an exhaust gas comprises a ceramic material containing 5 to 100% by weight of a calcium phosphate compound, as well as a filter cartridge and exhaust gas filter containing the filtering medium. Based on the excellent properties of the incorporated calcium phosphate compound, the agents and products according to the present invention exhibit a highly improved adsorptivity to oil-soluble substances, odor substances, animal or vegetable cells, viruses, biopolymeric substances or other substances, and therefore can be advantageously used in various fields of technology. For example, the functional paper can be used as a deodorant, filter medium and adsorbent as well as a flame-retardant paper.Type: GrantFiled: February 26, 1992Date of Patent: May 10, 1994Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Sumiaki Tsuru, Akihiko Yokoo, Takeshi Sakurai, Tetsuro Ogawa
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Patent number: 5240659Abstract: An oriented shaped article of a calcium phosphate type compound is disclosed, in which at least two crystallographic axes of the primary particles of which the shaped article is composed each is oriented in one direction, respectively, in at least the surface of said article. A sinter of the oriented shaped article and a processes for producing the article and the sinter are also disclosed.Type: GrantFiled: March 24, 1992Date of Patent: August 31, 1993Assignee: Asahi Kogaku K.K.Inventors: Takeshi Ichitsuka, Tetsuro Ogawa, Masaya Sumita, Akihiko Yokoo
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Patent number: 5217699Abstract: A calcium-phosphate type hydroxyapatite for chromatographic separation is in the form of spherulites having a mean particle diameter of 0.5 to 50 .mu.m, preferably 1 to 10 .mu.m. The spherulites are each an aggregate mainly of acicular crystallites belonging to a series of hexagonal systems and having unit lattice constants of 9.58.+-.0.08 .ANG. for the a axis and 7.00.+-.0.05 .ANG. for the c axis. The hydroxyapatite is produced by granulating a calcium=phosphate type hydroxyapatite in the form of a gel and then firing the granular apatite at 400.degree. to 700.degree. C., preferably at 500.degree. to 600.degree. C. The firing is performed by heating the granules in the presence of oxygen or air for a given period of time.Type: GrantFiled: July 17, 1991Date of Patent: June 8, 1993Assignees: Toa Nenryo Kogyo Kabushiki Kaisha, Ashaikogaku Kogyo Kabushiki KaishaInventors: Nobuaki Tagaya, Hideyuki Kuwakara, Takao Hashimoto, Noriko Komatsu, Keiko Fukamachi, Tsugio Maeshima, Toshihiro Ishikawa, Tetsuro Ogawa
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Patent number: 5158756Abstract: Porous particles of a calcium phosphate compound having a Ca/P ratio of 1.5 to 1.80, which contain open pores having an average pore size of 100 to 4000 .ANG. and are in the form of spherical particles having an average particle size of 1 to 40 .mu.m, and a process for their production. 90% of the total pore volume of the particles is occupied by pores having a pore size that is 0.5 to 2 times larger than the average pore size of the open pores and the total volume is at least 0.5 ml/g of the particles. The porous calcium phosphate particles are particularly useful as packings for liquid chromatography.Type: GrantFiled: June 25, 1990Date of Patent: October 27, 1992Assignee: Asahi Kogaku Kogyo Kabushiki KaishaInventors: Tetsuro Ogawa, Akihiko Yokoo, Kazuhiro Naganuma, Satoshi Fujinuma, Katsumi Kawamura
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Patent number: 5134009Abstract: An oriented shaped article of a calcium phosphate type compound is disclosed, in which at least two crystallographic axes of the primary particles of which the shaped article is composed each is oriented in one direction, respectively, in at least the surface of said article. A sinter of the oriented shaped article and a processes for producing the article and the sinter are also disclosed.Type: GrantFiled: September 14, 1989Date of Patent: July 28, 1992Assignee: Asahi Kogaku Kogyo K.K.Inventors: Takeshi Ichitsuka, Tetsuro Ogawa, Masaya Sumita, Akihiko Yokoo
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Patent number: RE35340Abstract: Column packing materials useful in applications such as liquid chromatography, as well as a process for producing such a packing material are described. A first aspect of the invention concerns a column packing material composed of a spherical substrate having a coating of a calcium phosphate based compound on the surface thereof.A second aspect of the invention concerns a packing material comprising porous calcium phosphate based granules having open pores with an average pore size of from 0.01 to 20 .mu.m, said granules being composed of crystalline particles with an average size of from 0.1 to 10 .mu.m.A third aspect of the invention concerns a spherical packing material for liquid chromatography comprising spherical particles of at least one material selected from the group consisting of Ca.sub.10 (PO.sub.4).sub.6 (OH).sub.2, Ca.sub.3 (PO.sub.4).sub.2, Ca.sub.2 P.sub.2 O.sub.7, Ca(PO.sub.3).sub.2, Ca.sub.10 (PO.sub.4).sub.6 F.sub.2 and Ca.sub.10 (PO.sub.4).sub.6 Cl.sub.Type: GrantFiled: August 13, 1993Date of Patent: October 1, 1996Assignee: Asahi Kogaku Kogyo K.K.Inventors: Takeshi Ichitsuka, Tetsuro Ogawa, Katsumi Kawamura, Masaya Sumita, Akihiko Yokoo