Abstract: The present invention relates to the field of food industry as well as to medicine, more particularly to novel compositions comprising hydrogen peroxide (H2O2) in combination with glycolic acid, glyoxylic acid, glycine, serine or salts thereof that allow using H2O2 as antimicrobial, especially antibacterial and antiviral or signaling agent yet neutralizing the toxic effects of the latter on the cell and tissues. The present invention also relates to a food product, an alcoholic/non-alcoholic beverage, or a nutritional supplement comprising the inventive composition and a method for production thereof.

Abstract: A method of treatment of a neurodegenerative disease which is associated with a decline in mitochondrial activity, includes administering to a person in need of such treatment at least one of Glycolic acid or a pharmaceutically acceptable salt or ester thereof, and D-lactic acid or a pharmaceutically acceptable salt or ester thereof.

Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of male infertility. The present invention also relates to an ex vivo method for increasing the mobility of spermatozoa comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with spermatozoa.

Abstract: A method of treatment of a neurodegenerative disease which is associated with a decline in mitochondrial activity, includes administering to a person in need of such treatment at least one of Glycolic acid or a pharmaceutically acceptable salt or ester thereof, and D-lactic acid or a pharmaceutically acceptable salt or ester thereof.

Abstract: The present invention relates to glycolic acid or a pharmaceutically acceptable salt or ester thereof for use in the treatment or prevention of male infertility. The present invention also relates to an ex vivo method for increasing the mobility of spermatozoa comprising contacting glycolic acid or a pharmaceutically acceptable salt or ester thereof with spermatozoa.

Abstract: The present invention relates to the use of specific carbazole derivatives in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.

Abstract: The present invention relates to specific sphingolipids/sphingolipid derivatives as pharmaceutical compositions as well as their use in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.

Abstract: The present invention relates to a compound comprising a tripartite structure in the format C-B-A or C?-B?-A? wherein moiety A and moiety A? is a raftophile, moiety B and moiety B? is a linker, moiety C and moiety C? is a pharmacophore; and wherein moiety B and B? is a linker which has a backbone of at least 8 carbon atoms and wherein one or more of said carbon atoms may be replaced by nitrogen, oxygen or sulfur. Furthermore, specific medical and pharmaceutical uses of the compounds of the invention are disclosed.

Abstract: The present invention relates to the use of specific steroid derivatives in the preparation of medicaments for the treatment or prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.

Abstract: The present invention relates to specific sphingolipids/sphingolipid derivatives as pharmaceutical compositions as well as their use in the preparation of medicaments for the treatment, prevention and/or amelioration of disorders relating to pathological processes in lipid rafts.