Abstract: A method to facilitate targeted advertising can include receiving a plurality of schedule files that include scheduling information for at least one respective advertising media asset. Target attribute data is associated with each of the plurality of schedule files to identify at least one characteristic of an intended target audience of media content represented in each of the plurality of schedule files. Profile data associated with each of a plurality of uniquely identifiable network devices is received. The profile data characterizes known attributes of an audience serviced by each of the plurality of uniquely identifiable network devices. A plurality of playlist data files are generated based on analysis of the target data and the profile data. Each of the plurality of playlist data files includes scheduling information for at least one respective advertising media asset scheduled for playing out by at least one of the plurality of uniquely identifiable network devices.